Sajan Patel @sajancpatel
Process Chemist, PhD @StanfordUChem (Burns Group), BS @UCB_Chemistry (Tilley Group) Joined July 2017-
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Congrats to @PaschkeAK, @Yannickbraegger, @BenceBBotlik, Erich Staudinger, @origree1! "Carbon-to-nitrogen atom swap enables direct access to benzimidazoles from drug-like indoles" nature.com/articles/s4155…. @NatureChemistry
We developed a novel reaction that enables a direct synthesis of amines from olefins via C=C bond cleavage. This process which we termed Triazenolysis represents an aza-version of ozonolysis reaction. Congrats to all involved @NatureChemistry @TechnionLive nature.com/articles/s4155…
🚨 A single-atom swap could change the game in drug discovery! 🧪💥 We have just unveiled a CO-to-S atom swap method that turns ketones into sulfur-containing frameworks in complex, bioactive molecules in just two steps. science.org/doi/10.1126/sc… Congratulations to Zining.
Please check out our latest achievement in C–C activation: Downsizing lactams via Rh-catalyzed C–C activation. sciencedirect.com/science/articl… Congratulations to Rui @zhangrchem and Kangmin @KangminWen04
We’re excited to share our work that introduces singly N-protected O-vinylhydroxylamines as ring-annulation reagents for the synthesis of azaindolines and azaindoles. Congrats to Zach & Charlotte (@charlie_bird13) and the Enamine (@EnamineLtd) team! 🔗 chemrxiv.org/engage/chemrxi…
TEN STEPS TO A MARINE TREASURE: Gram-Scale Synthesis of Bipinnatin J – featuring methods that weren't known ≅3 years ago to forge 3 key C–C bonds... Appearing today in @ChemRxiv (chemrxiv.org/engage/chemrxi…). Quick Summary: A concise, scalable total synthesis of (–)-Bipinnatin J…
I really happy to share our lastest publication in @J_A_C_S "Generation of Stereocenters via Single-Carbon-Atom Doping Using N-Isocyanides" Huge congrats to everyone involved! And excited to see my first paper as a corresponding author! pubs.acs.org/doi/10.1021/ja…
Check out our recent publication in @JOC_OL on the anti-Markovnikov oxidation of alkenes enabled by photoexcited nitroarenes under iron Lewis-acid catalysis. pubs.acs.org/doi/10.1021/ac…. #photochemistry #nyuchemistry #nitroarenes
Synthesis of Borane-Ammonia and its Application in the Titanium Tetrachloride Catalyzed Reduction of Carboxylic Acids, Including N-Protected Amino Acids Henry J. Hamann, Abdulkhaliq A. Alawaed, and P. Veeraraghavan Ramachandran orgsyn.org/demo.aspx?prep…
SAXITOXIN simplified: Appearing today in @ChemRxiv is a short, highly scalable, convergent approach to this entire natural product family using a tactical combination of radical retrosynthesis, biocatalysis (in collaboration with Merck), and C–H functionalization logic:…
We've been drawn to selective activation of C(alkenyl)–H bonds for a long time. In a new @ACSCatalysis paper, @sunjuntao1 & team turned attention to an interesting situation where functionalizing enamine-type azaheterocycles creates a chiral C–N axis. tinyurl.com/mpjjb99w
EnantioCH by our MPAA ligand fills a gap in chiral technology; creating new chemical space for both drug discovery and chiral ligands: pubs.acs.org/articlesonrequ…
Visible Light-Promoted Deracemization of α-Amino Aldehyde by Synergistic Chiral Primary Amine and Hypervalent Iodine Catalysis | Journal of the American Chemical Society @Tsinghua_Uni @TotalSyntheses pubs.acs.org/doi/10.1021/ja…
Ready to take off as a synthetic chemist? Check out this tutorial review we wrote with Frank Glorius and Jasper Tyler! @GloriusGroup @GloriusFrank
Ready to take off as a synthetic chemist? Check out this tutorial review we wrote with Frank Glorius and Jasper Tyler! @GloriusGroup @GloriusFrank
Congrats to @gloganb, @SojungKim20, Yusuke and collaborators @BarnerKowollik, @GileadSciences, @Merck on our indazole to benzimidazole conversion onlinelibrary.wiley.com/doi/10.1002/an… coordinated with @LeonoriLab onlinelibrary.wiley.com/doi/10.1002/an…
'How do I thianthrenate X?' – In our new article in @J_A_C_S, @DilgamAhmadli presents simple guidelines for selecting reaction conditions and with our collaborators from @Syngenta developed a robust diversification platform for further functionalizations! pubs.acs.org/doi/10.1021/ja…
Synthesis of naphthalene derivatives via nitrogen-to-carbon transmutation of isoquinolines | Science Advances science.org/doi/10.1126/sc…
Happy to share our review on "Recent Developments for the Ring Opening of Pyrrolidines and Unstrained Cyclic Amines via C–N Bond Cleavage" in EurJOC @ChemEurope !! Congrats to Eisuke !! doi.org/10.1002/ejoc.2…

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