Carter Brzezinski @sp3intermediate
Biocatalysis, Pharmacology, Swimming. @KFBChem Postdoc @WuestLab alumni (‘25) @KenyonCollege swammer & alumni (‘20) he / him / his 🇯🇵 Atlanta, GA Joined September 2019-
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Carter Brzezinski retweeted
Do Amino-Oxetanes Resemble Amides? Check out our Matched Molecular Pairs study in @ChemRxiv comparing properties and structure. Congrats @hikaruishikura and coworkers, in collaboration with Pfizer. doi.org/10.26434/chemr…
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Carter Brzezinski retweeted
In our total synthesis of psathyrin A fresh @J_A_C_S, we challenged the MHAT radical chemistry to build four-membered ring and it worked! Total Synthesis of (−)-Psathyrin A Enabled by Radical Cyclization | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…
Congrats team VHPO!!!
Carter Brzezinski retweeted
KFB Lab Alert: Congratulations to @ManiksharmaASR and @sp3intermediate for receiving outstanding poster awards at the Natural Products GRC! #coolbiocats
boss is gonna be so mad at me (setting up an air sensitive rxn) #NotBiocatUnfortunately
Carter Brzezinski retweeted
Out today in @J_A_C_S is the first synthesis from our group!! We report a convergent and stereoselective total synthesis of the nominal structure of Talaromyolide D. Huge congrats to Bo and Alex! @nyuchemistry @TotalSynthesis pubs.acs.org/doi/10.1021/ja…
Carter Brzezinski retweeted
The most dominant single-event run in sports history 🐐
Had the pleasure of chairing this year’s Natural Product and Bioactive Compounds GRS! It was great to finally connect with this amazing group of scientists and discuss some really amazing chemistry. Additional thanks to my co-chair for Pankaj Mahajan for helping organize!
Carter Brzezinski retweeted
Fantastic work by the Ward lab to repurpose cytochrome #P450 enzymes for a new-to-nature asymmetric metal-catalysed H atom transfer! Just released @Nature: doi.org/10.1038/s41586…. A must read!
Carter Brzezinski retweeted
I'm excited to share with y'all in @J_A_C_S our C-H Functionalization of dihydropyrroles and the @TotalSynthesis of (-)-Dragocin D. Congratz to our team, the Huw Davies Group, at @EmoryChem @BeyondCCHF for bringing this to fruition! Check it out at doi.org/10.1021/jacs.5…
Carter Brzezinski retweeted
Something a little different from our group. We designed a regeneration system for ATP(gamma)S, a reagent that normally costs ~$30,000/g. This allows for more practical enzymatic thiophosphorylation to make a number of interesting/funky thiophosphates. chemrxiv.org/engage/chemrxi…
Carter Brzezinski retweeted
Convergent #TotalSynthesis of Erchinines A and B and Their C20 Epimers by Yong Sun Cho, Joseph P. Tuccinardi, and John L. Wood @JohnWoodGroup at @BaylorCBC in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Carter Brzezinski retweeted
I'm excited to share my lab's first preprint! It describes Affinity Map, a highly general method providing proteomic profiles of binding affinity for small molecules, peptides, and antibodies in cell lysate, organ extracts, and live cell surfaces. biorxiv.org/content/10.110…
Carter Brzezinski retweeted
Excited to share our total synthesis of aporphine alkaloids! Inspired by biosynthesis, we use a non-natural intermolecular photochemical phenol coupling to access analogues for serotonin & adrenergic receptor profiling. @KozlowskiMarisa @TotalSynthesis pubs.acs.org/doi/10.1021/ac…
Carter Brzezinski retweeted
Check out this new direct #CHfunctionalization method for fused azines at #ACScentralscience : broad, metal-free and proceeding with exclusive and predictable #regiocontrol! Executed in #parallelmode for its immediate application to #drugdiscovery! 💊 pubs.acs.org/doi/10.1021/ac…
Carter Brzezinski retweeted
Our approach to the total synthesis of chartelline C, out now in JACS. Photochemistry and unique topology gave way to some really interesting reactivity! pubs.acs.org/doi/10.1021/ja…
Inspiring stuff from Davies group here at Emory. Induced fit in a rhodium catalyst (III —> TS-C4)! pubs.acs.org/doi/10.1021/ja…
Holy reduction potential!!! -3.9 vs SCE
Carter Brzezinski retweeted
Check out this @NSF news featuring our work @J_A_C_S on phaeocaulisin A total synthesis and biological studies! Cheers @EmoryUniversity @emorycollege @EmoryChem! Lab-synthesized botanical compound shows promise for fighting aggressive breast cancer nsf.gov/news/lab-synth…
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