Nobel laureate John Jumper (@JohnJumperSci) on AlphaFold and the future of science. At AI Startup School in San Francisco. 01:02 - Journey from Physics to Computational Biology 02:01 - Transition to Machine Learning and AI 02:59 - Joining Google DeepMind 03:47 - The Mission: Accelerating Scientific Discovery 04:54 - Understanding Protein Structures 07:44 - Challenges in Protein Structure Determination 11:21 - The Role of Data, Compute, and Research 13:28 - AlphaFold: A Breakthrough in Protein Prediction 14:09 - The Importance of Research and Ideas 17:48 - Real-World Applications and Impact 18:02 - Open Sourcing AlphaFold 21:07 - Unexpected Uses and Innovations 23:15 - Case Study: Molecular Syringe 25:28 - Future of AI in Science
@ycombinator @JohnJumperSci AlphaFold’s breakthrough in protein prediction showcases AI’s transformative role in tackling complex biological challenges.
@ycombinator @JohnJumperSci Data + ideas + compute = a recipe for revolution. Love how AlphaFold went from a moonshot to open source—accelerating solutions far beyond DeepMind’s original mission. What will the next “unexpected use” be?
@ycombinator @JohnJumperSci "The real cost of compute is the cost of ideas that didn't work"
@ycombinator @paulg @JohnJumperSci The support cheers in the beginning makes me happy and I automatically love the audience 😁
@ycombinator @JohnJumperSci I hate to see all the talk of "innovation" and "scientific discovery" has no bearing on those of us paying all kinds of pricecs for this clan to stand on the stage & excite ppl to close their eyes on the pain & torment they R causing us w their BS.
@ycombinator @JohnJumperSci A local AI, no internet needed, capable of receiving commands via radio, interpreting real-time alerts, and learning autonomously. Runs on any PC. This is not an idea — it’s an active, patented system. @ycombinator, shall we talk? #AI #radioAI #DeepTech
@ycombinator @JohnJumperSci Future of AI-driven discovery, any limits?
@ycombinator @JohnJumperSci AlphaFold: Unraveling life's code, one protein at a time. Science meets sci-fi in our own DNA.
@ycombinator @JohnJumperSci @ycombinator, really interesting to see how interdisciplinary expertise led to such a breakthrough in protein folding. The best innovations often happen at the intersection of fields.
@ycombinator @JohnJumperSci sounds like a lot of buzz, but let's see if the impact matches the hype. real science takes time, not just flashy presentations.
