Alessandro Vitriolo @AVitriolScience
I use computational tools to understand transcriptional regulation, neurodevelopment, and human evolution. Milan, Lombardy Joined March 2019-
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In February 2024, I wrote Scientific Reports about a published meta-analysis claiming that mindfulness interventions affect neural plasticity, 'cementing the neuropsychological basis of mindfulness-based interventions'. Paper was retracted yesterday—here a process summary.🧵
TOMORROW: DDD seminar, July 8, 2025 @ 1PM Eastern US: Dr. Alessandro Vitriolo @AVitriolScience (Lab of Dr Giuseppe Testa @gtesta72) “Regulatory logic of human cortex evolution by combinatorial perturbations”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote upper layer cortical neurogenesis through NRXN1-mediated contacts with outer radial glia. biorxiv.org/content/10.110…
The unbearable slowness of being: Humans still clock in at just 10 bits/s. Even after peer review :) Share link for Neuron: authors.elsevier.com/a/1kHVa3BtfH9B…, ArXiv: arxiv.org/abs/2408.10234
📢 Paper alert! Our paper on cortical brain organoids multiplexing is out @naturemethods. nature.com/articles/s4159… Together with the Research Briefing nature.com/articles/s4159… /1
When I find this stuff in my old notes it feels like finding money in old abandoned clothes arxiv.org/abs/0804.2996
Is evolution predictable or highly contingent? This new @RSocPublishing paper explains why life here & elsewhere might be universal regarding its logic, from molecular information & cells to viruses &ecosystems. @sfiscience @philipcball @seanmcarroll royalsocietypublishing.org/doi/10.1098/rs…
Very happy @OlivieroLeonar2 will present @EMBLEvents the results of a wonderful collaboration with @ellylewerissa @naelnadif @gtesta72, where we show that CHD2 dosage controls the rate of human cortical development & underlies neoteny traits not shared with Neanderthals #EESHuman
Years of collective reasoning and working summarized in a few slides. Kudos to @cedricboeckx for presenting it to such a special audience! #EESHuman #organoids #CRISPR #evodevo
Years of collective reasoning and working summarized in a few slides. Kudos to @cedricboeckx for presenting it to such a special audience! #EESHuman #organoids #CRISPR #evodevo
A huge thanks for the support to @gtesta72 and @cedricboeckx taking me on board for this project, and all the colleagues working on it: Cristina Cheroni, @apetrella_ @castaldi_davide @OlivieroLeonar2 @Aless_Valente @CulottaLorenza @matbonf @Fil_Mirabella1 @AVitriolScience !
🔬 Our @PeroneGaia and Jasmine Nguyen from the @3P1L Group developed #SOLIST, a cryo-lift out technique revolutionizing molecular imaging that captures tissue organization at a nanoscale with unmatched efficiency Published in @naturemethods humantechnopole.it/en/news/solist…
Very proud to share my first work at @humantechnopole! Kinbiont: From time series to ecological and evolutionary responses in microbial systems. biorxiv.org/content/10.110… #compbio #microbiology 1/6
Still a week left to apply! Trust the former attendees :) youtu.be/XGBawiJVbhU?si…
Still a week left to apply! Trust the former attendees :) youtu.be/XGBawiJVbhU?si…
Congratulations Bianca 🎉🎉🎉
Too bad I could not attend. kudos to my fellow organisers and thanks to @bowlofscience and the Scientific Training Office who supported it. @humantechnopole
Too bad I could not attend. kudos to my fellow organisers and thanks to @bowlofscience and the Scientific Training Office who supported it. @humantechnopole
This is peer review. Since we are unimportant and have written something 'similar', then it is a desk rejection. Ridiculous. Better to say that the article does not meet quality standards. It just makes one angry and is another sign of how the system needs to be reformed.

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