Michele Gabriele 🔬🧬📸 @labronic_mike
from 🇮🇹 | former @AICF_nyc and K99 fellow @MIT | #newlab in SR-TIGET June 2025 | #Chromatin | #Microscopy | #FirstGen gabrielelab.com Cambridge, Massachusetts Joined December 2016-
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At SR-Tiget we are seeking outstanding mid-career scientists in Computational biology, AI, and Molecular immunology who wish to translate their results into therapeutic advances with a focus on genetic diseases! Deadline 1st September 2025! linkedin.com/posts/sr-tiget…
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Michele Gabriele 🔬🧬📸 retweeted
Proud to announce the latest release of 🧬#Oxbow🏹, with new features to make NGS data analysis more powerful, efficient, and "composable". Learn more at: oxbow.readthedocs.io
Have you recently finished your PhD and had excellent productivity? Telethon foundation is starting a postdoctoral program with a competetive 3-years fully funded position! Send CV and PI preference (included me, I am not yet in the website) details here: back.fondazionetelethon.it/uploads/2025/0…
Are you a mid-career group leader in computational bio/AI/molecular immunology who wants to move the lab to Italy? (preferentially from USA?) The SR-TIGET (Milan, Italy) is recruiting someone like you! Here the call: back.fondazionetelethon.it/uploads/2025/0…
Michele Gabriele 🔬🧬📸 retweeted
3/ We ran simulations to estimate EP search times based on 1) measured subdiffusion, 2) physical/genomic distance. Within 300nm (~<200 kb), a gene can find 1000s of enhancers in minutes. Such encounters can’t be selective → EP selectivity needs other mechanisms, e.g. biochemical
This new preprint from my labmates provides a new perspective on chromatin dynamics! Strongly suggested to everyone into chromatin given its broad impact!
This new preprint from my labmates provides a new perspective on chromatin dynamics! Strongly suggested to everyone into chromatin given its broad impact!
New exciting discoveries about ADNP and its role in neurodevelopment!
New exciting discoveries about ADNP and its role in neurodevelopment!
I am happy to share that our preprint about the modeling of #YY1 haploinsufficiency has been published as open access! You can find it here: nature.com/articles/s4138… #organoids #gabrieledevriessyndrome #ipscs #epigenetics @gtesta72 @AVitriolScience @FPereiraMarlene
I am happy to share that our preprint about the modeling of #YY1 haploinsufficiency has been published as open access! You can find it here: nature.com/articles/s4138… #organoids #gabrieledevriessyndrome #ipscs #epigenetics @gtesta72 @AVitriolScience @FPereiraMarlene
Michele Gabriele 🔬🧬📸 retweeted
What a beautiful home for our multiplexed organoids! Kudos to all the members of the @gtesta72 lab who contributed to the project. And a big shoutout to Philipp Dexheimer for this absolute piece of art!🎨
What a beautiful home for our multiplexed organoids! Kudos to all the members of the @gtesta72 lab who contributed to the project. And a big shoutout to Philipp Dexheimer for this absolute piece of art!🎨
Michele Gabriele 🔬🧬📸 retweeted
Super excited to share our new study from the @JD_Buenrostro Lab in @Nature! We developed a computational method for tracking transcription factor and nucleosome binding using single-cell ATAC-seq and deep learning. Paper: nature.com/articles/s4158…
I made a B$sky profile, you can find me here: bsky.app/profile/michel…
Starting 2025 with a genome architecture paper about absolute quantification of looped states, lead by James Jusuf!
Starting 2025 with a genome architecture paper about absolute quantification of looped states, lead by James Jusuf!
Michele Gabriele 🔬🧬📸 retweeted
Our preprint by @DomenicNarducci and the companion preprint by @deWitLab are now out in @MolecularCell ZNF143 is not a general looping factor and was identified as such due to a non-specific antibody. Instead it is TF with the longest residence time measured (to our knowledge)
Our preprint by @DomenicNarducci and the companion preprint by @deWitLab are now out in @MolecularCell ZNF143 is not a general looping factor and was identified as such due to a non-specific antibody. Instead it is TF with the longest residence time measured (to our knowledge) https://t.co/FqeFEN5nsp
Michele Gabriele 🔬🧬📸 retweeted
📢 Paper alert! Our paper on cortical brain organoids multiplexing is out @naturemethods. nature.com/articles/s4159… Together with the Research Briefing nature.com/articles/s4159… /1
Michele Gabriele 🔬🧬📸 retweeted
1/10🚨 New Findings Alert! 🚨 Discover how genomic heterogeneity and ploidy help predict intrinsic resistance to anti-PD-1 immune checkpoint blockade (ICB) in metastatic melanoma. 🧬science.org/doi/10.1126/sc… 📝 Key takeaways from our latest study: 🧵👇
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