Alles Lab @AllesLab
Associate Professor/PI, Anesthesia. Molecular & cellular physiology and neuroscience of #chronicpain. Tweets are my own. 🚵♂️🏃⛰️ alleslab.com Cincinnati, OH Joined December 2010-
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Excited to get things going here @CincyChildrens!!
Excited to get things going here @CincyChildrens!!
The Chamessian Lab @WashUPain is recruiting a #postdoctoral research associate to build on the foundational findings from our recent preprint showing that ion channels can be degraded by PROTACs. #TPD #PROTAC #drugdiscovery #pain #ionchannels. We're a fun group with an…
I am pleased to share @silvernonferous (Dr. Adewale Fadaka) newest report on a novel neuroimmune mechanism of inflammatory muscle pain in neonates. The intersection of endocrine signaling and neuroimmune communication ... sciencedirect.com/science/articl…
Great way to kick off 2025 with a visit to see my buddy & fellow human tissue enthusiast @mikehildebrand7 at @cu_research in my hometown 🇨🇦 #painresearch
It is with great pride that I share the bulk of thesis work from my first PhD Candidate @goinsyeah on neuroimmune mechanisms of chronic back pain! This is a new direction for the lab led by Aleyah's sheer curiosity and drive to understand #chronicpain biorxiv.org/content/10.110…
McIlvried, @JohnDR01, @robgereau et al. @WashUPain show that mechanisms of adaptive plasticity are engaged in mouse and human sensory neurons after sustained depolarization. hubs.la/Q02_YmnR0 #CellularPhysiology #MolecularPhysiology
Looks like all members of the @AllesLab will be moving! Most of us to Cincy & one of us for a great postdoc opportunity elsewhere. Excited to see great things from each of you! 💪👩🔬🔬 #PainResearch
Looks like a great opportunity. If any prospective postdocs are interested in applying for translational medicine project funding to work in my lab in 2026, please reach out! #ChronicPain
Looks like a great opportunity. If any prospective postdocs are interested in applying for translational medicine project funding to work in my lab in 2026, please reach out! #ChronicPain
Our latest work in collaboration with the @JBIdelaPena lab on the effects of neuropathic pain drug gabapentin on human DRG neurons is now online!! Spoiler alert: interesting donor-specific actions! #PainResearch #humanDRG biorxiv.org/content/10.110…
If we look at thousands of proteins (i.e., signals) in the human blood, the protein most associated with chronic physical and mental illnesses is the **same protein** as the top marker for mitochondrial diseases: GDF15 When mitochondria cannot flux energy properly, the cell…
We're honored to once again been named to @usnews Best Children’s Hospitals Honor Roll for the 2024-25 rankings. We ranked No. 1 in three specialties, and we placed in the top 10 for all 10 ranked specialties - cincinnatichildrens.org/news/release/2…
Thrilled to announce that the @AllesLab & family are moving to Cincinnati! We will join the Dept of Anesthesiology @CincyChildrens next year. We look forward to continuing our work on molecular/cellular mechanisms of #chronicpain & starting exciting new projects soon 🎉🥂
The Alles Lab is now on Blue Sky! bsky.app/profile/allesl…
Stellar work!
Recording from hDRG on this chilly snow day! #neuroscience #pain #snow
Always exciting to kick off the ASSURE program application season. Know of any college students in #StLouis who are looking for an introduction to research? ASSURE is specifically intended for students who have not had easy access to similar opportunities. #ASSURE2025
Always exciting to kick off the ASSURE program application season. Know of any college students in #StLouis who are looking for an introduction to research? ASSURE is specifically intended for students who have not had easy access to similar opportunities. #ASSURE2025
Our latest work in @NatureBiotech describing a new molecule with potential for non-opioid pain relief. We developed a prodrug that releases monomethyl fumarate at sites of oxidative stress, relieving pain in models of neuropathy and osteoarthritis nature.com/articles/s4158…
New paper by Jorge Palop's lab @CellReports we collaborated. We report a #MachineLearning platform for unbiased & sensitive behavioral analysis of #Alzheimers mice & protection from AD behavioral alterations by genetic #fibrin inhibition. cell.com/cell-reports/f…
Excited to join the Editorial Board of @TheJournal_Pain ! sciencedirect.com/journal/the-jo…
BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

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