Andy Shih @AndyShih_Lab
Neuroscientist, sorting out the brain's plumbing in health and disease. theshihlab.com Seattle, Washington Joined February 2021-
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Happy to see this work finally published 🙌!! A team effort with @AndyShih_Lab!! We show that from birth to old age, #microglia 🧠 undergo striking shifts in morphology, complexity, and injury response. #liveimaging #neuroimmune #neonatalbrain #agingbrain
Happy to see this work finally published 🙌!! A team effort with @AndyShih_Lab!! We show that from birth to old age, #microglia 🧠 undergo striking shifts in morphology, complexity, and injury response. #liveimaging #neuroimmune #neonatalbrain #agingbrain
It is debated whether poor #blood flow underlies white matter loss in #aging. Our recent study in aged mice supports this idea: Impaired drainage through rare, deep-reaching #venules causes mild #hypoperfusion that triggers inflammation and demyelination. nature.com/articles/s4159…
Groundbreaking scientific discoveries don’t happen in isolation. Michelle Gray, PhD, SfN Program Committee member, shares how you can enhance your research through valuable exchange w/ the scientific community at #SfN25. Submit your abstract today! 🔗 bit.ly/4juLSLs
Very happy to share @stephkbeee's study in @PNASNews on the effects of capillary injury in the brain. Protect those heads! Stephanie is starting her own lab at @CUAnschutz soon and excited to see her research grow!
Very happy to share @stephkbeee's study in @PNASNews on the effects of capillary injury in the brain. Protect those heads! Stephanie is starting her own lab at @CUAnschutz soon and excited to see her research grow!
Growth hormone acts on #pericytes, stimulating #angiogenesis and supporting #oligodendrocyte survival & growth after neonatal hypoxia. An impressive study by the Mei Lab (cell.com/neuron/fulltex…) in @NeuroCellPress. Preview written with @vcoelhosantos (cell.com/neuron/abstrac…)
This mini review was a fun one for @sosamariaj and I where we dove into the mysteries of brain perivascular fibroblasts! Thank you to @AndyShih_Lab for guidance on this one! Please enjoy 😊! frontiersin.org/articles/10.33…
MARK YOUR CALENDAR: The @dfg_public CRC1366 will host the "Vascular Control of Organ Function" meeting in Mannheim in May 2024. Exciting program with diverse contributions from different fields of angiocrine research. Registration will open in October at SFB1366.de .
Excited to be collaborating with @Mishra_CBF_Lab on this newly funded project to study pericytes roles in Alzheimer's disease. An amazing mentor and training environment.
Excited to be collaborating with @Mishra_CBF_Lab on this newly funded project to study pericytes roles in Alzheimer's disease. An amazing mentor and training environment.
The O'Herron lab is highly recommended for trainees interested in innovative approaches to image and manipulate brain vasculature.
We team up with @drew_lab_nvc to examine anatomical and functional changes in aged mouse brain. We found that aging induces selective regional vascular and pericyte degeneration, slowed NVC response, and lower oxygen carrying capacity. biorxiv.org/content/10.110…
This technique makes it almost effortless to label neurons for in vivo calcium imaging and neurovascular coupling studies. New study from @Prakash3Photon lab. frontiersin.org/articles/10.33…. AAV tool from @VivianGradinaru @DevermanLab.
This technique makes it almost effortless to label neurons for in vivo calcium imaging and neurovascular coupling studies. New study from @Prakash3Photon lab. frontiersin.org/articles/10.33…. AAV tool from @VivianGradinaru @DevermanLab. https://t.co/96iBaU2FeX
The first review from the @vcoelhosantos lab! Surprisingly little known about how early life hypoxic events affect cerebrovascular function and resilience in adulthood.
The first review from the @vcoelhosantos lab! Surprisingly little known about how early life hypoxic events affect cerebrovascular function and resilience in adulthood.

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