Jinmiao Chen Lab @CJM_lab
Chen Jinmiao Lab for single cell Immunology and AI Singapore Joined April 2023-
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Very excited to share our recent paper titled 'Single-nucleus transcriptomics reveals a distinct microglial state and increased MSR1-mediated phagocytosis as common features across dementia subtypes' published in @GenomeMedicine genomemedicine.biomedcentral.com/articles/10.11…
Happy to announce that our Nature Methods paper 'SpatialGlue' was recently featured in A*STAR Research: research.a-star.edu.sg/articles/highl…
We would like to announce that disco has moved to disco.bii.a-star.edu.sg. Thank you for your support ☺️
Congratulations to Azimuth 2. Delighted that Disco is contributing to this initiative 😊
Excited to share our latest @NatureMedicine study from our new center @ARC_Neuro! 🧠✨ Using spatial transcriptomics & scRNA-seq, we uncover how Aβ-targeting immunotherapies shape microglial responses in AD patient brains. A thread with our key findings is below! 🧵(1/15)
Congratulations and very nice study @DGateLab 🙂
Spatial transcriptomics reveals distinct microglial mechanisms driving amyloid-β clearance in both passive and actively immunized #Alzheimer’s disease patients @NUFeinbergMed nature.com/articles/s4159…
Lab Gathering Lunch and Chinese New Year celebration 🎉🎉🥳 Also all the best to @LongYahui and chengwei as they embark on their new journeys 😊
🎉 Congrats to the Singapore research team on ezSingleCell! 🎉 A game-changer for #singlecell & #spatialbiology, it simplifies data analysis from platforms like Chromium, Visium & Xenium without programming expertise! 🚀 Learn more: nature.com/articles/s4146…
🚀 DISCO December Update 🚀 📊 8,529,538 cells from 1,345 samples across 94 projects added in this month's update! 🎉 Dive in and explore the data that matters to you! 🧬 Check it out here: immunesinglecell.org #Bioinformatics #SingleCell #LLM #DISCO
🎉 Excited to share that our paper DISCO: a database of Deeply Integrated human Single-Cell Omics data has reached 100 citations! 🚀 Grateful for all the researchers utilizing and building upon DISCO. Here's to advancing single-cell biology together! 💡📊 #SingleCell…
@FEBSnews @FEBS_JS @FEBSOpenBio @FEBSJournal Our keynote of Career Day is a FEBS-powered breakout lecture by Dr. Jinmiao Chen (@CJM_lab)! 🌟 She introduces the fundamentals of spatial omics and shares her lab's cutting-edge AI-driven analysis method, STAMP (Zhong et al., 2024). 🚀
🚀 scEnrichment Update! The scEnrichment tool now features an updated reference geneset with 524 cell type 🧬 and phenotype 🔬-related genesets! 🎯 Input your geneset to uncover enriched phenotypes or cell types with ease. 🔗 Try it here immunesinglecell.org/tool/sc_enrich… #scRNAseq…
Rediscovering publicly available single-cell data with the DISCO platform academic.oup.com/nar/article/do…
🚀 Exciting update! DISCO now supports batch downloads—access data from 113,277,088 cells across 18,402 samples with ease. Perfect for training your LLMs or fueling other applications! 🌐📊 #SingleCellData #Bioinformatics #AI @LlM immunesinglecell.org/download
Our data showed varied functions of myeloid cells in early life while identifying therapeutic targets. We are grateful to our collaborators @FGinhoux @HongyanWang9 @lai9uan @CJM_lab @Abhay_R_ and their teams for all their support, ideas, tools, and enthusiasm over the years!
Exiting new method, looking forward to trying it!
Exiting new method, looking forward to trying it!
Congratulations to our bioinformatics collaborator @CJM_lab for yet another excellent method to decipher the #spatialtranscriptomics data. I look forward to the future of deeper understanding of #tumourmicroenvironment with our powerful partner!
Congratulations to our bioinformatics collaborator @CJM_lab for yet another excellent method to decipher the #spatialtranscriptomics data. I look forward to the future of deeper understanding of #tumourmicroenvironment with our powerful partner!
Interpretable spatially aware dimension reduction of spatial transcriptomics with STAMP nature.com/articles/s4159… #journals #feedly
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