The Cell Research (CR) publishes original research results that are of unusual significance or broad conceptual or technical advances in all areas of life scienJoined June 2019
CRISPR-Cas keeps on giving. Never thought it could do RNA-activated protease activity. Beautiful mechanistic work with @AilongK group. Thanks Chunyi Hu and Sam van Beljouw, and all co-authors.
science.org/doi/10.1126/sc…
Very beautiful work with high potential for applicaiton development.
Craspase is a CRISPR RNA-guided, RNA-activated protease science.org/doi/10.1126/sc…
Researchers use X-ray crystallography to reveal the structure of "T-box" elements in Mycobacterium tuberculosis.
T-boxes recognize when a cell is deficient in a specific amino acid & are only found in bacteria, making them good drug targets.
phys.org/news/2019-11-s…
Excited to share my work on tRNA recognition by a full-length T-box RNA in @NatureSMB. An elaborate structure allows the T-box to decode and sense the aminoacylation status of the tRNA. Could their ancestors be #RNAworld tRNA-synthetases? rdcu.be/bW3zV
Fun review article by our lab on how a viral domain invaded the fungal ancestor, expanded through duplication, and became associated with important fungal traits. authors.elsevier.com/a/1ZsEB,LqAZJg…
Hi guys, How about this article: Interferon-inducible cytoplasmic lncLrrc55-AS promotes antiviral innate responses by strengthening IRF3 phosphorylation / nature.com/articles/s4142… / rdcu.be/bHqSQ / # Innate immunity # Long non-coding RNAs
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933 Followers 299 FollowingWe are interested in everything about RNA, including CRISPR-Cas, novel RNA-guided enzymes, riboswitches, & bacterial immunity. We develop genome editing tools.
373 Followers 1K FollowingDiscover The Power of The World's #1
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237 Followers 597 FollowingAssociate Professor with interests in Cancer Research | Signal Transduction | Molecular Cell Biology | Cell Metabolism | Kinases | Inflammation. Opinions my own
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