Bappaditya Chandra @ChandraLabNDSU
Assistant Professor of Chemistry & Biochemistry at North Dakota State University. Interested in understanding the role of phase-separation in transcription. chandra-lab.com Fargo, USA Joined June 2010-
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Diffusing protein binders to intrinsically disordered proteins by David Baker group. nature.com/articles/s4158…
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Interesting work.
Bappaditya Chandra retweeted
Architectural RNAs: blueprints for functional membraneless organelle assembly: Trends in Genetics cell.com/trends/genetic…
Bappaditya Chandra retweeted
Latest work on RNA condensation from the Banerjee lab, led by a superstar graduate student, Tharun Mahendran. Biomolecular condensates can enhance RNA percolation, leading to the emergence of multi-phasic RNA condensates. nature.com/articles/s4155…
Bappaditya Chandra retweeted
CD8-targeted lipid nanoparticles carrying anti-CD19 CAR mRNA were developed to generate CAR-T cells directly in vivo, demonstrating effective B cell depletion for potential treatment of B cell malignancies and autoimmune diseases. science.org/doi/10.1126/sc… #NBThighlight
Bappaditya Chandra retweeted
How rogue jumping genes can spur Alzheimer’s, ALS: knowablemagazine.org/content/articl…
Bappaditya Chandra retweeted
New findings reveal how NUP98 protein fusions drive childhood acute myeloid leukemia and identify a promising combination therapy that significantly improves survival in treatment-resistant models. ow.ly/TsLS50WcjtK
Bappaditya Chandra retweeted
‘Killswitch’ protein lets scientists study immobilized cellular droplets nature.com/articles/d4158…
Interesting article; some bat species have evolved enhanced p53 tumor suppressor activity, giving them extraordinary resistance to cancer despite their long lifespans. nature.com/articles/s4146… #SmartNews
Very interesting study...
Bappaditya Chandra retweeted
Phase separation of the oncogenic fusion protein EWS::FLI1 is modulated by its DNA-binding domain | PNAS pnas.org/doi/10.1073/pn…
Bappaditya Chandra retweeted
A pair of split inteins—small protein segments that can undergo a self-sustained protein splicing reaction—enables endogenous protein editing in living mammalian cells, according to a new study in Science. 📄: scim.ag/3ENypj9 #SciencePerspective: scim.ag/430jwC9
Bappaditya Chandra retweeted
Martini3-IDP: improved Martini 3 force field for disordered proteins. doi.org/10.1038/s41467…
Bappaditya Chandra retweeted
I'm so thrilled to read an interview of my former PhD student, Priyanka Dogra @PriyankaDogra07, now a postdoc at St. Jude @StJudeResearch @StJude with @kriwacki. In this interview, she describes her exciting scientific journey and her fascinating research. stjude.org/research/progr…
Bappaditya Chandra retweeted
Sequence-encoded intermolecular base pairing modulates fluidity in DNA and RNA condensates: nature.com/articles/s4146…
I had an amazing experience teaching biochemistry to the graduate students. Happy faces before the final exam. @NDSU
Bappaditya Chandra retweeted
"Native nucleosomes know where to go!” Our Condense-seq paper is now published in Nature! 📄 nature.com/articles/s4158… I’m deeply grateful to my PhD advisor @taekjip and our incredible collaborators @MuirLab , @binzmit , Erika Pearce, and Ben Garcia lab!!
Bappaditya Chandra retweeted
Essential reading for all imaging enthusiasts/microscopists. The do’s and don’ts of scientific image editing nature.com/articles/d4158…
Bappaditya Chandra retweeted
Today, we are launching the first publicly available AI Scientist, via the FutureHouse Platform. Our AI Scientist agents can perform a wide variety of scientific tasks better than humans. By chaining them together, we've already started to discover new biology really fast. With…
Bappaditya Chandra retweeted
I am excited to share the latest paper from my lab where we leverage the selection bias of condensate-promoting oncofusions to uncover molecular rules governing condensate specificity and function. cell.com/cell/fulltext/….
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