Chang Jiang 姜畅 @ChangJiangLab
Assistant member @MoffittNews studying redox biology, cancer metabolism and mitochondria. lab.moffitt.org/jiang/ Tampa, FL Joined August 2023-
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Chang Jiang 姜畅 retweeted
Congratulations Hank Adelmann @hankadel on this beautiful in vivo follow to his discovery of MFSD12 as a lysosomal cysteine transporter. Lysosomal reduced thiols are essential for mouse embryonic development | PNAS pnas.org/doi/10.1073/pn…
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Chang Jiang 姜畅 retweeted
New @CellReports paper by @andrewaguirremd @DanaFarber_Hale Integrative genomic identification of therapeutic targets for #PancreaticCancer cell.com/cell-reports/f… VERY GOOD use of public datasets (DepMap, CCLE, TCGA, GTEx) to identify cell intrinsic & cell surface dependencies
Chang Jiang 姜畅 retweeted
Moffitt Study Uncovers New Mechanism of Immunotherapy Resistance | Moffitt moffitt.org/newsroom/news-… Exciting research from the Tsai lab published in Nature!
Chang Jiang 姜畅 retweeted
New work from our lab describing a role for mitochondrial glutathione in breast cancer metastasis @nicoledelgaudio @RockefellerUniv aacrjournals.org/cancerdiscover…
Xue-Yan has indeed cool stuffs to share!😇
Xue-Yan has indeed cool stuffs to share!😇
So proud of my little team! 💪Grateful for each of you- your motivation, hard work, and willingness to learn together inspires me everyday! 🙌We still have rotation student spots open -join us if you have interest in redox biology and selenium metabolism! @MoffittNews
Chang Jiang 姜畅 retweeted
Join us in at Moffitt! The Metabolism Program is recruiting at the Assistant Member (Assistant Professor) level. Review of applications starts September 1st. Please share! Details here: …cancer-center-careers.hctsportals.com/jobs/1883440-t…
Chang Jiang 姜畅 retweeted
Preprint from @dow_lab @WeillCornell using CRISPR base editing screens: Genetic mechanisms of resistance to targeted KRAS inhibition biorxiv.org/content/10.110… MAPK reactivation remains the predominant mechanism of resistance to KRASinh. Also identifies a hotspot mutation in CiC.
Chang Jiang 姜畅 retweeted
HIF-independent oxygen sensing via KDM6A regulates ferroptosis dlvr.it/TMNJD5
Really exciting work! Enjoy it indeed!
Really exciting work! Enjoy it indeed!
Chang Jiang 姜畅 retweeted
Excited to share our new preprint led by Kirandeep Deol! Genetic screens uncover mechanisms regulating FSP1 abundance in cancer. Vitamin B2 metabolism promotes FSP1 stability via FAD synth / binding, further linking nutrient metabolism to #ferroptosis. biorxiv.org/content/10.110…
Chang Jiang 姜畅 retweeted
SmartImpute is now online with Cell Reports Methods cell.com/cell-reports-m…
Chang Jiang 姜畅 retweeted
From solving math puzzles in third grade to developing new therapies for HPV-related cancers, Jennifer Binning, PhD (@JenBinning) has always loved a challenge. Today, she combines her passion for research with a drive to make a difference in oncology. At Moffitt, she leads…
Chang Jiang 姜畅 retweeted
Now online in @CD_AACR: Mitochondrial Glutathione Import Enables Breast Cancer Metastasis via Integrated Stress Response Signaling - by Hsi-wen Yeh, @nicoledelgaudio, @KivancBirsoy, and colleagues doi.org/10.1158/2159-8… @RockefellerUniv
Chang Jiang 姜畅 retweeted
The first FASEB Ferroptosis conference! ✔️ Thank you to my co-organizer Scott Dixon, our sponsors, and the whole #Ferroptosis community for showing up and making this such a wonderful meeting! 🤩 ❤️ #Ferroptosis25
Congratulations! Stan! Well deserved! 👍
Congratulations! Stan! Well deserved! 👍
Chang Jiang 姜畅 retweeted
Big day for the David lab! 🎉 Our @MolecularCell paper is out today- huge congrats to first authors @IfeAkano & Jake Hebert for leading this beautiful study uncovering SMARCA3 as a novel H3 E3 ligase that shapes heterochromatin regulation in colorectal cancer 🤩
Big day for the David lab! 🎉 Our @MolecularCell paper is out today- huge congrats to first authors @IfeAkano & Jake Hebert for leading this beautiful study uncovering SMARCA3 as a novel H3 E3 ligase that shapes heterochromatin regulation in colorectal cancer 🤩
Congratulations!
Chang Jiang 姜畅 retweeted
I was honored for Dr. Jiang, Assistant Member in the Dept of Molecular Oncology in the Division of Basic Science @MoffittNews , to share her exciting work on metabolic pathways driven by NRF2 in lung cancer! #MoffittAACR25 #AACR2025
I was honored for Dr. Jiang, Assistant Member in the Dept of Molecular Oncology in the Division of Basic Science @MoffittNews , to share her exciting work on metabolic pathways driven by NRF2 in lung cancer! #MoffittAACR25 #AACR2025
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