Dan Graham @DanGrahamMD
General Pathologist at Clinical Labs of Hawaii / Interest in BST, H&N, GU, GYN, Heme kikoxp.com/daniel_graham Straub Hosp, Honolulu, HI, USA Joined June 2009-
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40s M Lung mass. Very unexpected findings... #ThoracicPath #PathX #PathTwitter
New predictive biomarker for gastric cancer - can you identify it based on this pattern of expression? #GIpath #IHCpath #PathTwitter
@DanGrahamMD Under the microscope, a sight to behold, A stroma so myxoid, cells young and old. With vessels interspersed, and cells that float free, A landscape so diverse, in this cardiac sea.
60s M with left atrial mass. #PathX #PathTwitter #CardiacPath #ThoracicPath
This spinal mass was a tough case (at least for me). The first two pics show a poorly diff component adjacent to a more mod diff area (this area stained positive with brachyury on the biopsy). Signed out as dedifferentiated chordoma. Very cool. #PathTwitter #BSTPath
#slidearchiveseries clear cell adenocarcinoma of urinary bladder #gupath #pathtwitter 🔬solid, tubulocystic, and papillary growth patterns; hobnail cells with eosinophilic or clear cytoplasm ➕ CK7, PAX8, HNF1β, p53, Napsin ➖ GATA3, p63, ER, PR, WT1
60s F multiple small bilateral lung nodules. Dx, ddx, stains? #ThoracicPath #PathX #PathTwitter
CD117 strong diffuse + CK7 scattered single cells GATA3 neg Oncocytoma it is! Great job everyone, you nailed it.
CD117 strong diffuse + CK7 scattered single cells GATA3 neg Oncocytoma it is! Great job everyone, you nailed it.
IHC panel: CKAE1/3: positive calretinin: positive WT1: weak focal positive TTF1: negative desmin: negative claudin4: negative Enough to call mesothelioma, or need more meso markers?
IHC panel: CKAE1/3: positive calretinin: positive WT1: weak focal positive TTF1: negative desmin: negative claudin4: negative Enough to call mesothelioma, or need more meso markers? https://t.co/HTmhzh1P15
60s M 6.5 cm renal mass extending into perinephric fat. What do you think the diagnosis is? Would you get an IHC panel to help resolve any ddx you have? #GUPath #PathX #PathTwitter
70s F with pleural and pericardial masses/studding as well as innumerable parenchymal lung masses. Bx of pleural mass. Ddx? Dx? Immunopanel? #ThoracicPath #PathX #PathTwitter
Challenging conventional belief, we found that atypical spindle cell/pleomorphic lipomatous tumor (ASPLT) can rarely undergo sarcomatous transformation. Excited to share insights on this phenomenon! #bstpath modernpathology.org/article/S0893-…
Thanks for all the responses. Indeed, the question here is: "Is it an angiofibroma of soft tissue, or just a vocal cord polyp?" I don't think we'll ever know for sure, as it's not worth doing fusion analysis etc. A beautiful benign case nonetheless!
Thanks for all the responses. Indeed, the question here is: "Is it an angiofibroma of soft tissue, or just a vocal cord polyp?" I don't think we'll ever know for sure, as it's not worth doing fusion analysis etc. A beautiful benign case nonetheless!
Cool new applications of GRM1 immunohistochemistry to diagnose chondromyxoid fibroma! #BSTpath #IHCpath #Cytopath Subcutaneous CMF: pubmed.ncbi.nlm.nih.gov/36810795/ CMF with FGF23 expression mimicking PMT: pubmed.ncbi.nlm.nih.gov/38303543/ Cytopathology diagnosis of CMF: pubmed.ncbi.nlm.nih.gov/38281480/
70s M w/ 1.3cm laryngeal mass near vocal cords. clinically suspicious for neoplasm. Thoughts? #PathX #PathTwitter
Mediastinal mass in young adult male. Mixed inflammatory background and Hodgkin/Reed-Sternberg cells. IHC in next tweets... #hemepath #pathology
Now this is bone AND soft tissue pathology! #BSTpath
It's calcified, it's chondroid, it's mesenchymal...what's not to like? #BSTpath pubmed.ncbi.nlm.nih.gov/37102574/
Look out - it's the myxoid, MUC4-positive variant of superficial CD34-positive fibroblastic tumor (PRDM10-rearranged soft tissue tumor) #BSTpath
The fabulous Dr. Miles and her 🔥 poster and data on BRAF- mutated AML at #SCT24 Come talk to her if you’re here. @lindemilesphd @AkEisfeld And a esp. thanks and shoutout to @bowman_rl for his awesome analysis pipeline.
Dora @1yzkKvLX264ZfBs
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@DanGrahamMD Thank you for your kind words! I'm glad you liked the poem, Dr. Graham.
@DanGrahamMD This thing often embolizes, causing infarcts. A truly scary tumor. 😱
@DanGrahamMD Cardiac myxoma: Most often it sits, in the atrium left, A mass so peculiar, of softness bereft. Jelly-like, gelatinous, it may appear, Causing symptoms that sometimes are severe.
@DanGrahamMD Under the microscope, a sight to behold, A stroma so myxoid, cells young and old. With vessels interspersed, and cells that float free, A landscape so diverse, in this cardiac sea.
___ of the ovary often presents in ___ syndrome A) Gonadoblastoma B) Gynandroblastoma C) Sex Cord Tumor with Annular Tubules (SCTAT) D) Sertoli Leydig Cell Tumor (SLCT) #GYNPath #PediPath #PathResidents #PathTwitter 🥳#pathmatch24! 💪#pathmatch25!
you can’t really control how you feel but you can certainly control the actions you take in response.
Congratulations to the incoming residents at @UCSFPath. ! Looking forward to meeting and working with you all.@ekhanafshar @BalassanianRon
Congratulations and welcome to the stellar incoming class of residents at UCSF Pathology and Laboratory Medicine. #PathologyIsTheTruth
Got my #1!!! 😭😭😭 Couldn't believe it!! Can't wait to meet my corezzzies!!!!
Please join us in congratulating our #PathMatch24 incoming PGY-1 class! We are proud to have you in our @NYUGSOM_Path Pathology family! Welcome to New York 🗽#PathTwitter #PathMatch24 #PathMatch2024 #path2path
@DanGrahamMD @TjLimMD @Teclis82 Great case. Thanks for sharing.
@VHNguyenMD @TristanRutland7 @JMGardnerMD @DrCycloPath @SumantaDas_7 @DrNishatAfroz2 @01sth02 @DrGeeONE @DanGrahamMD @Immanuel_Paul30 Thank you! 😊 I'm glad you liked it!
This spinal mass was a tough case (at least for me). The first two pics show a poorly diff component adjacent to a more mod diff area (this area stained positive with brachyury on the biopsy). Signed out as dedifferentiated chordoma. Very cool. #PathTwitter #BSTPath