Doc Edge @DocEdge85
Assistant professor in quantitative and computational biology @USC. Genetics, evolution, and a bit of statistics. edgepopgen.github.io/edgelab/ Joined November 2015-
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Doc Edge retweeted
Another genetic genealogy case from the US where the FBI used the MyHeritage DNA database without the consent of their users. The prosecution are also refusing to provide discovery of the relevant information. masslive.com/news/2025/08/f…
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Doc Edge retweeted
Scientific tragedy
Doc Edge retweeted
📣Online NOW! 📄Estimation of demography and mutation rates from one million haploid genomes 🧑🤝🧑 @jgschraiber @DocEdge85 & co cell.com/ajhg/abstract/…
Doc Edge retweeted
This is a really good lay article on embryo selection but IMO is overly credulous of risk reductions that emerge as a consequence of statistical assumptions rather than actual disease etiology. The disease model *really* matters ...
This is a really good lay article on embryo selection but IMO is overly credulous of risk reductions that emerge as a consequence of statistical assumptions rather than actual disease etiology. The disease model *really* matters ... https://t.co/nQG9RxwnC8
Doc Edge retweeted
People still think "Gattaca" is just a fairy tale, because a eugenic dystopia must be something imposed on us rather than something we all voluntarily choose.
People still think "Gattaca" is just a fairy tale, because a eugenic dystopia must be something imposed on us rather than something we all voluntarily choose.
Doc Edge retweeted
I'm thrilled that my lab at NYU is now supported by an NIH MIRA grant! I'm looking to hire 1-2 senior lab members (outstanding postdoc candidates or experienced staff scientists) with expertise in computational and statistical methods in human genetics or genomics. Please share!
Doc Edge retweeted
Very happy to share our new paper now on @medrxivpreprint: “Genetic risk effects act in sets”, a great effort led my PhD student @JolienRietkerk, and performed together with collaborators @andywdahl, @AndrewSchork, @jonathan_flint1 etc. Thread 1/n
Doc Edge retweeted
New preprint with Guy Sella on the question: what is polygenicity? biorxiv.org/content/10.110…
One of my favorite categories of thing is "guy decides to spend decades on an insane, idiosyncratic, solo art project of staggering scope". Other entries include the Watts Towers, Coral Castle, Forestiere Underground Gardens, Le Palais Ideal
One of my favorite categories of thing is "guy decides to spend decades on an insane, idiosyncratic, solo art project of staggering scope". Other entries include the Watts Towers, Coral Castle, Forestiere Underground Gardens, Le Palais Ideal
Doc Edge retweeted
latest paper from the lab led by PhD student Gilia Patterson. Gilia has developed a spatially explicit deep learning method for close kin mark recapture that we think will be extremely useful for conservation biology biorxiv.org/content/10.110…
Doc Edge retweeted
Mutation-selection-drift balance models of complex diseases biorxiv.org/content/10.110… #biorxiv_genetic
Doc Edge retweeted
When should adaptation arise from a polygenic response versus few large effect changes? biorxiv.org/content/10.110… #biorxiv_evobio
Doc Edge retweeted
I went on WBUR today to talk about the grant terminations and the importance of basic medical research wbur.org/news/2025/05/1…
Doc Edge retweeted
In the right conditions, antibiotic resistance can happen extremely fast. Here is an example from my own work of bacteria overcoming an antibiotic in just eleven days in a giant petri dish: 1/
Doc Edge retweeted
This entire line of research, after being repeatedly selected in rigorous open national competitions for funding, was cut this week as collective political retribution x.com/baym/status/19…
This entire line of research, after being repeatedly selected in rigorous open national competitions for funding, was cut this week as collective political retribution x.com/baym/status/19…
Doc Edge retweeted
Hanania advocated passionately against "race mixing" for years, so he knows what he's talking about here. But it's worth adding that race-IQ obsessives also tend to make very poor predictions about the future. Let's review ...
Hanania advocated passionately against "race mixing" for years, so he knows what he's talking about here. But it's worth adding that race-IQ obsessives also tend to make very poor predictions about the future. Let's review ...
Doc Edge retweeted
In population #GENETICS, Q-ST and F-ST calculations help compare the amount of trait differentiation on one or more traits in genome-wide genetic variants. Using simulations Liu and @DocEdge85, show the effect of various choices made while computing Q-ST. buff.ly/313bkfU
Doc Edge retweeted
In a new #GENETICS research, @Dandan_Peng, Mulder, and @DocEdge85 evaluate the performance of several ancestral recombination graph (ARG) estimation methods used for determining the historical time course of a population-mean polygenic score. Read more: buff.ly/Xr9nFjB
Doc Edge retweeted
My paper about type I error rates in Qst/Fst comparisons is now published in @GeneticsGSA. Check it out here: academic.oup.com/genetics/advan…
My paper about type I error rates in Qst/Fst comparisons is now published in @GeneticsGSA. Check it out here: academic.oup.com/genetics/advan…
Doc Edge retweeted
VERY excited to announce a pre-print that represents the culmination of several years of work*: “On ARGs, pedigrees, and genetic relatedness matrices” doi.org/10.1101/2025.0… Led by @BrieucLehmann with contributions from @epigenci @LukeAnderTroc @jeromekelleher @petrelharp
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