Sophie Dumont @DumontLab
Mechanics of cell division @UCSF dumontlab.ucsf.edu San Francisco, CA Joined May 2015-
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Excited to share our work out in @CurrentBiology today! We find that NuMA acts as a spindle "glue" - independent of its partner dynein. Congrats to student Nathan Cho who led the work, and thanks to Merve, Aryan and @Yildiz_Lab for in vitro help. cell.com/current-biolog…
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Excited to share NuMA preprint #2/2! We report structural and functional insights into how NuMA activates and regulates dynein at cell division. Congrats to Merve Aslan @Yildiz_Lab, @AmicoEnnio @Carter_Lab and Nathan Cho from our lab. And others inc. Maddie Blaauw from our lab.…
Excited to share NuMA preprint #1/2! We find that NuMA mechanically reinforces the spindle independently of its partner dynein. Congrats to student Nathan Cho who led the work, with Merve Aslan and @Yildiz_Lab. biorxiv.org/content/10.110…
Excited to share our work out in @CurrentBiology ! We find that SKAP's binding to microtubules *reduces* friction at the kinetochore-microtubule interface and increases attachment stability under force. Congrats to postdoc Miquel @RosasSalvans and all authors! With @Caleb_J_Rux…
Nominate a colleague or yourself for the Motility and Cytoskeleton Early Career Award at the 2025 Biophysical Society Meeting! To do so fill out this form and email Radhika Subramanian and I your CVs by Dec 1 2024: docs.google.com/forms/d/e/1FAI…
Nominate a colleague or yourself to speak at the Motility & Cytoskeleton Subgroup at the 2025 Biophysical Society Meeting! Radhika Subramanian and I are organizing the subgroup and looking for nominations by July 8th: forms.gle/i3AMosmEugx2cn….
Excited to share our work @JCellBiol! We find that torques within and outside the spindle oppose each other to limit spindle twist during anaphase. Congrats to @LilaNeahring who led the work! Thanks to Nathan Cho, @Caleb_J_Rux, @Yildiz_Lab, Upadhyayula and Subramanian Labs.…
Excited to share our work @JCellBiol! We find that chromosome size-dependent spindle forces impair mammalian mitotic error correction of long chromosomes. Congrats to graduate student @megan_chong who led this work! With Miquel @RosasSalvans @VannaTran5 rupress.org/jcb/article/22…
Excited to share our work out in @PLOSONE with @goga_lab showing that expressing an oncogene protects spindle poles from fracturing in mechanically confined environments. Congrats to first authors @RenaldoSutanto and @LilaNeahring and all authors! journals.plos.org/plosone/articl…
Congratulations to graduate student @megan_chong from our lab who received a UCSF Dean’s Award for Excellence in Mentoring! Megan is an inspiring mentor to many in our lab and out. And congrats to all other awardees! @UCSFGradDiv
Lab dinner with past and present lab members at #CellBio2023 😊
Our lab is exicted to be at @ASCBiology #cellbio2023 in Boston. Come check out what we've been up to! @c3STC
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