Edward Nirenberg 🇺🇦 @ENirenberg
Views my own, but you can borrow them if you feel so inclined. Anti-disease. Big Nerd Energy. “A homework person.” Fun at parties. Antibody hoarder. he/him deplatformdisease.com United States Joined September 2016-
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My book, 'In Defence of Fauci', is now available for pre-order: amazon.com/dp/B0CW1CCQLV It provides a comprehensive, chapter-by-chapter refutation of the arguments in Robert F. Kennedy Jr's book, 'The Real Anthony Fauci.'
Evolution of nasal and olfactory infection characteristics of SARS-CoV-2 variants: buff.ly/3U7APN4 @HopkinsMedicine #COVID_19 #Neuroscience
Correlates of protection against symptomatic SARS-CoV-2 in vaccinated children. Privileged to collaborate with @YoujiaZhong @NUSMedicine @dukenus. Many thanks to @NatureMedicine for publishing our findings. nature.com/articles/s4159…
There is no real rational reason for why but it is disappointing to learn that some people don’t tolerate spicy food well
CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age nature.com/articles/s4146…
WHO COVID vaccine advisers recommend switch to JN.1 strain cidrap.umn.edu/covid-19/who-c…
If you’re in the market for some H5N1 cattle sequences, look no further. 👇🏻 virological.org/t/note-about-a…
If someone writes in their book about killing their dog, imagine the things they’ve done that didn’t make it in.
some really really cool structural virology papers coming out this year nature.com/articles/s4159…
It is GREAT that we can now protect infants in the US against RSV with nirsevimab; RSV is the #1 cause of hospitalization for kids under 1 in the US But 99% of global deaths & 88% of hospital admissions from RSV are in low & middle income nations, where the drug is unaffordable
Online now: Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses dlvr.it/T60szs
Due to enormous and collaborative effort from the @nextstrain team, @hamesjadfield @trvrb and of course @USDA , we now have the USDA cattle sequences on Nextstrain: nextstrain.org/avian-flu/h5n1… visualized with new, 2-year builds.
With identification of PB2-M631L, PA-K497R, PA-E613K in cattle lineage... there is a timely preprint from @wendybarclay11 and Grimes labs with a CryoEM structure of #H5N1 (A/turkey/Turkey/1/2005) FluPolA polymerase complex with human ANP32B. researchsquare.com/article/rs-371…
With identification of PB2-M631L, PA-K497R, PA-E613K in cattle lineage... there is a timely preprint from @wendybarclay11 and Grimes labs with a CryoEM structure of #H5N1 (A/turkey/Turkey/1/2005) FluPolA polymerase complex with human ANP32B. researchsquare.com/article/rs-371…
Perspective @CellCellPress @VirusesImmunity @RMedzhitov Exploring new perspectives in immunology doi.org/10.1016/j.cell…
Reminder: If you would like to analyze bovine H5N1 influenza A virus consensus sequences from SRA data shared by @USDA_APHIS , @xrayfoo has assembled them and we have shared them here. Please repost (if willing). github.com/andersen-lab/a…
Following influenza virus rechallenge, lung resident but not circulating memory B cells differentiate into plasma cells near infected alveoli (outside iBALTs) with signals from innate (NK) cells @JExpMed @Tal_Arnon_Lab doi.org/10.1084/jem.20…
REVIEW @iScience_CP Optimized Lipid Nanoparticles for Organ-Selective Nucleic Acids Delivery In Vivo cell.com/iscience/fullt…
this place grows progressively less charming with each moment
COVID-19 Vaccination and Pediatric SARS-CoV-2 Infection and Hospitalization in CA 3.9 million children: vaccination estimated to avert 146 210 cases of COVId19 in 12-15 yo and 230134 cases in 5-11 yo. 168 hospitalizations averted in children 6-59 mos. jamanetwork.com/journals/jaman…
Health Nerd @GidMK
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654 Followers 3K Following Capitalism is broken Media lies Wall St steals Govt too big and inept STONE COLD BROKEBen Knight @knight186811
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1 Followers 338 FollowingPastor Paul @pastorpaulsef
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454K Followers 8K Following Virologist. PI @VIDOInterVac. Adj Prof @USask BMI. P2 @covarr_net. Jeopardy! loser. Famed for my obnoxious turns of phrase. 🇺🇸in🇨🇦. she/herDavid Gorski, MD, PhD @gorskon
78K Followers 2K Following Surgeon/scientist promoting science-based medicine. Editor, Science-Based Medicine blog. (He/him.) Also at https://t.co/2LecwK3CP9.Eric Burnett, MD @Doctor_Eric_B
23K Followers 824 Following Board certified IM doc, academic hospitalist, asst. professor of medicine, husband, dog dad, educator. He/him 🏳️🌈views = my ownTyler Black, MD @tylerblack32
55K Followers 4K Following Suicidologist, emergency psychiatrist and pharmacologist. Data geek, ok, lots of other geek. Views expressed are my own and not my employers'. he/him/hisProf Gavin Yamey @gav.. @GYamey
41K Followers 8K Following Professor of Global Health & Public Policy @DukeU. Director, Center for Policy Impact in Global Health. DJ @wxdu. TIME columnist. He/him. Tallest Jew on Earth.Dr. Neuro 🏳️�.. @Neurofourier
25K Followers 2K Following (Not active) Infectious disease | Public Health | Global Health | Epidemiology | @ CDC | He/him 🇺🇸 🏳🌈🦠 | Opinion =My ownThe Real Truther @thereal_truther
49K Followers 6K Following Host of The Real Truther Show on X Spaces! President of the RTN Network.™ Spreading truth about vaccines since 2015.Prof. Akiko Iwasaki @VirusesImmunity
220K Followers 2K Following We study antiviral immunity and viral disease pathogenesis. #COVID19 #longCOVID #vaccines @HHMINEWS @YaleIBIO @YaleMed @YaleCII President of @ImmunologyAAIDebunk the Funk @Debunk_the_Funk
33K Followers 850 Following 👋🏾 I’m Dan, I’m a Ph.D. in molecular biology that covers bad science while making good science accessible.Jeremy Kamil is also .. @macroliter
25K Followers 5K Following He, him. CMV virologist exploring how viruses exploit glycoimmune checkpoints #Glycotime | Loves 🥾 🏔️ 🏕️| Y'all on Bluesky or Threads? Linktree below ⬇️Alastair McAlpine, MD @AlastairMcA30
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110 Followers 143 Following Graduate student at UC Berkeley in @barton_lab. Studying interactions between the immune system and commensal bacteria. Avid mouse poop collectorPasare Lab @ThePasareLab
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757 Followers 1K Following @TheAcademy nominated filmmaker of #shotinthearmmovie with EP @neiltyson World Vaccine Day - SHOT IN THE ARM Screening Event - https://t.co/KwgYmFgk9YṢẹ̀yẹ Abímb�.. @seyeabimbola
18K Followers 2K Following Health Systems | Knowledge Practices | Realist | Institutionalist | Academic, University of Sydneycaryn 🦉 @carynjrogers
1K Followers 5K Following Senior science writer for @preeclampsia, some philbio/ social epistemology. The best way to judge is to get a boat and fill the boat with tacos. #NAFO 🇺🇸Michael Calderwood, M.. @CalderwoodMD
3K Followers 701 Following Infectious Diseases Physician, Chief Quality Officer @DHMCandClinics, Associate Professor of Medicine @GeiselMedSouradet Shaw @SouradetS
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5K Followers 515 Following Assistant Professor at MIT Chemistry and Core Member at Broad Institute of MIT and Harvard@rdd147 I mean, you don’t have to be condescending and rude about it. I am an immunologist/virologist and I am curious whether humans would have any protection if the virus does jump. Obviously we are not there yet, but preparedness is important here too.
There can be only one singular Tom.
So is she gonna be "Zendaya Holland" or is he going to become "Tom"
Of course, as we learned during the pandemic, a smaller % of a large number of people is a large number of people. So regardless of the exact number, the time to prepare is now. Prepare for the worst, hope for the best.
3. We may have some cross-protection with regular flu strains, too. We've all seen N1 (second part of H5N1) a bunch of times through vaccines or infection. Also H5 and H1 are both “group 1” hemagglutinins, which may provide protection too.
2. Viruses have to make trade-offs when they mutate for human-to-human spread. Usually, this is in the form of trading disease severity for transmissibility. Studies in 2015 showed when you give H5 the mutations needed to spread effectively between ferrets, it loses its severity
Will 50% of people die if #H5N1 jumps? Very unlikely. Yes, this is @WHO's stat BUT three important points... 1. H5N1 deaths are among a small pool of known cases. Past antibody studies of H5 suggest we are missing many infections. science.org/doi/10.1126/sc…
This leads to the next question: Why are cats dying at 50% rate while cows are not? We have no idea. There is so much we don’t understand about the pathways here. Will humans follow cat's patterns of mortality? We don't think so (see #1-3 above). (big h/t to @ENirenberg)
You know your boss is supportive when you send him a draft letter of support where you hyped yourself up more than you ever have in your life and he responds Make it stronger.
My book, 'In Defence of Fauci', is now available for pre-order: amazon.com/dp/B0CW1CCQLV It provides a comprehensive, chapter-by-chapter refutation of the arguments in Robert F. Kennedy Jr's book, 'The Real Anthony Fauci.'
Today, I was operated upon in an OR shared by several departments, including aesthetic surgery. No mixup occurred, and I didn't wake up with augmented breasts or something.
@TBrnaughtTB Looking at Staphylococcus aureus from a not so clearly infected source.
primary consideration for many ID consults: is this lil guy pathogenic or just hangin out?
@ENirenberg We're sorry to disappoint you. ;-) FWIW, I'm disappointed in my taste buds lack of spice tolerance, too.
Evolution of nasal and olfactory infection characteristics of SARS-CoV-2 variants: buff.ly/3U7APN4 @HopkinsMedicine #COVID_19 #Neuroscience
Twitter in a nutshell 😅🙄
@DCC_DMAP Biochemistry is wondering where in your 18-step protein purification method your target either precipitated or denatured.
Chemistry is puzzling over a boc group that survived 4 M HCl/Dioxane overnight
Mathematics is finding interesting puzzles and solving them Physics is looking at the solution to the most interesting puzzle there ever was and trying to figure out how nature did it
Correlates of protection against symptomatic SARS-CoV-2 in vaccinated children. Privileged to collaborate with @YoujiaZhong @NUSMedicine @dukenus. Many thanks to @NatureMedicine for publishing our findings. nature.com/articles/s4159…