Eric M. Desjardins @EricMDesjardins
Venture associate for Pre-Amp @amplitudeVC. Ph.D. @DrGregSteinberg @MacMODR- McMaster University Hamilton, Ontario Joined January 2019-
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A strong #lifesciences sector in Canada can help reduce strain on health systems, support more research and development, and attract more clinical trials that offer new hope for patients. New article in @BIOTECanada's Insights mag: issuu.com/biotecanada_in…
We are excited to join forces with @Evotec to turbocharge precision medicine with the launch of our new venture studio, Pre-Amp! This partnership integrates Amplitude's expertise in venture creation with Evotec's industrialized drug discovery platforms evotec.com/en/investor-re…
“Ten years ago I was kicked out and forced to retire.” Our new medicine laureate Katalin Karikó (@kkariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges. Ten years ago, Karikó was still doing all her…
Combination therapy for #NASH in mice-ACLY inhibition + GLP-1R agonism @CellRepMed @DrGregSteinberg cell.com/cell-reports-m…
Check out our new paper in @CellReports, led by @EricMDesjardins and @DrGregSteinberg, demonstrating combined benefits for ACLY inhibition and GLP1 treatment on fatty liver disease @CellPressNews cell.com/cell-reports-m…
The combination of a GLP-1RA and bempedoic acid reduces liver fat and fibrosis. @LoganTownsend86 cell.com/cell-reports-m…
We Ask the Canadian Government to Increase CIHR’s Budget - Signez la pétition ! chng.it/LLwFwcQq via @CdnChange
Congratulations to Professor Hertzel Gerstein on his election to the Royal Society of Canada recognizing his scholarly accomplishments in the study of #diabetes @RSCTheAcademies @McMasterU @PHRIresearch @CIHR_IRSC @DiabetesCanada @_DiabetesAction @AmDiabetesAssn
"Our study highlights the potential of the hormone GDF15 to not only reduce the desire to eat fatty foods but also simultaneously boost energy burning in muscle.” @DrGregSteinberg describing new findings out now in @Nature …bolism-research.healthsci.mcmaster.ca/mcmaster-unive…
🚨New findings from @McMasterU's @DrGregSteinberg & @wddong1988 out now in @Nature "GDF15 promotes weight loss by enhancing energy expenditure in muscle" …bolism-research.healthsci.mcmaster.ca/research/
Energy burn in muscle boosted by a hormonal signalling axis nature.com/articles/d4158…
A GDF-15- GFRAL–β-adrenergic-dependent signalling axis that increases fatty acid oxidation and calcium futile cycling in the skeletal muscle of mice, thereby maintaining energy expenditure in skeletal muscle during caloric restriction @DrGregSteinberg nature.com/articles/s4158…
Skeletal muscle, not adipose tissue, mediates cold-induced metabolic benefits @DenisPBlondin @wddong1988 @NatMetabolism nature.com/articles/s4225…
We are looking for a new colleague! #PhD position available to study the molecular regulation of salt inducible kinases, a member of AMPK family, in metabolic health & disease. Join us for some cool science, amazing co-workers & an incredible work environment at @Metabolcenter 👇
We are looking for a new colleague! #PhD position available to study the molecular regulation of salt inducible kinases, a member of AMPK family, in metabolic health & disease. Join us for some cool science, amazing co-workers & an incredible work environment at @Metabolcenter 👇
All about AMPK academic.oup.com/edrv/advance-a…
Great to see our findings from 7 years ago showing that bempedoic acid is converted to a CoA derivative that inhibits ACLY and lowers atherosclerosis without myotoxicity nature.com/articles/ncomm… now saving lives in people with CVD. nejm.org/doi/full/10.10…
Emily Day @EmDay4
251 Followers 252 Following Postdoctoral Fellow at Trinity College Dublin. McMaster University Alumni.Stuart Phillips (he/h.. @mackinprof
54K Followers 5K Following Dad, Husband, Distinguished Univ Professor, tier 1 @CRC_CRC, @McMasterU; opinions mine. Scholar: https://t.co/9FZmrkltUw. Linktree: https://t.co/6w6NWx9M6p@MacMODR @MacMODR
662 Followers 192 Following McMaster's Centre for Metabolism, Obesity & Diabetes Research translates world leading basic science into clinical practice to improve metabolic disease.Greg_Steinberg @DrGregSteinberg
845 Followers 66 Following Professor of Medicine at McMaster University studying metabolism. Co-Director of @MacMODR.Tanner Stokes, Ph.D. @tjstokes5
428 Followers 604 Following Ph.D. in Kinesiology from McMaster University | Interested in skeletal muscle adaptation in response to exercise and inactivity.Logan Townsend @LoganTownsend86
430 Followers 393 Following CIHR Post-Doc at McMaster @MacMODR. Liver & adipose metabolism in health and obesity. Flames, Chiefs, and Mavericks fan.Nathan Hodson @nathanhodson5
747 Followers 877 Following Lecturer in Musculoskeletal Physiology - Manchester Metropolitan University - Interested in the mechanisms underpinning skeletal muscle hypertrophy/atrophy.PHRI.ca Population He.. @PHRIresearch
5K Followers 5K Following Birthplace of 9 most measurable modifiable risk factors for #heartdisease #stroke @McMasterU @hamhealthsci ACT on #clinicaltrials Newsletter: https://t.co/mpqGNzFps8Alex Green @AlexEGreen
277 Followers 666 Following MSc, PhD - PDF at uOttawa in Muscle, Metabolism and Mito Views are my own https://t.co/1Cm4PiU0ml https://t.co/vnSUPLuvpnJoe Gordon @josephwgordon
2K Followers 2K Following Scientist at the Children's Hospital Research Institute of Manitoba, Associate Professor at the University of Manitoba.Battsetseg Batchuluun.. @batchuluun_b
752 Followers 807 Following CIHR Postdoc and Sessional Instructor @McMasterU l Metabolic disease research | Motivational quotes | Positive mind | Workout | Sci-fi moviesJem Cheng @jemcheng
895 Followers 635 Following @CIHR_IRSC Postdoctoral Research Associate, Thermal Ergonomics Laboratory @HeatHealth_USYD, University of Sydney.Jim Johnson, PhD @JimJohnsonSci
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3K Followers 2K Following Professor & Chair, Biochemistry & Biomedical Sciences @McMasterU, studying Crohn's disease, superbugs, and immunity. Proudly leading the Coombes lab since 2006Robert Morton @RobMorton23
2K Followers 741 Following Senior Scientific Manager @novonordiskfond | CIHR Fellow in Genetic & Molecular Epidemiology @PHRIresearch | PhD in Kinesiology @McMasterU | he/him | 🇩🇰/🇨🇦Stothioth @StothiothN6S
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17 Followers 33 Following McMaster University | investigating cell sources for cultivated meatTheykeen @theykeen46286
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243 Followers 442 Following Venture Associate @ Pre-Amp @amplitudeVC @ISTAustria & @UBCMicroImmuno alum she/her | 🔬🎿 🚴🏻♀️ 🇨🇦Jaya Gautam @gautamjmcmaste1
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213 Followers 747 Following PhD student, Faculty of Pharmacy and Pharmaceutical Sciences University of AlbertaScott Isaacs @scottisaacsmd
13K Followers 2K Following President-Elect @theaace, endocrinologist, obesity medicine, #MASLD, Emory Med School adjunct faculty. Posts are my own.International Journal.. @IJPS_ASP
1K Followers 3K Following We publish original research on issues in population processes; dynamics of fertility, mortality, and migration; socioeconomic and environmental change.Stanislovas S. Jankau.. @SsJankauskas
2K Followers 5K Following Postdoc at @EinsteinMed. Mitochondria, aging, diabetes, CVD and CKD.🔬Confocal microscopy pro. 📷 as a hobby.Alice Man @aleyecem
68 Followers 99 Following MD-PhD student @McMasterU @PHRIresearch 👩🔬 Alum @UBC 👩🎓 (she/her)The Swan Group @The_Swan_Group
152 Followers 2K Following The Swan Group is a boutique search firm specializing in Technology, Analytics and Data Science needs within the Biotech, Pharmaceutical and Life Sciences.Catherine Bellissimo @cat_bellissimo
294 Followers 395 Following Postdoctoral Fellow @ecgoligher| PhD @ChrisPerryMito @MHRC_YorkU| Muscle Physiology | Duchenne muscular dystrophy| Mitochondria| Respiratory Muscle | DiaphragmGraham P Holloway @HollowayMitoLab
390 Followers 111 Following Physiology lab at the University of Guelph.Wilson (Yuqin Wu) @Wilson79078233
563 Followers 4K Following PhD candidate at Monash BDI, study in Glucagon signalling in metabolic control (supervised by Dr Adam Rose, the head of Nutrient Metabolism and Signalling lab)Allied.vc @AlliedVC
2K Followers 2K Following Western Canada’s largest angel syndicate, investing in early-stage tech startups across Canada & the USA. Pitch us, Invest, Scout👇Alex Caron @AlexandrCaron
513 Followers 753 Following 🇨🇦 NeuroMetabolic Pharmacology. Assistant professor @universitelaval. Obesity/Type2Diabetes/Metabolism Researcher @IUCPQFrancesca Keefe (she/.. @keefe_francesca
184 Followers 1K Following Senior Research Development OfficerDr Anna Stenning @anna_stenning
2K Followers 4K Following She/they; music lover and nature enthusiast. Research Associate at Durham University; own views. Co-editor of Neurodiversity Studies.Kevin Tharp @Derpology
1K Followers 2K Following Ignorance driven researcher applying haute couture blockchain omics-seq-oscopy to understand cellular mechano-metabolic relationships in cancer and aging.Katarzyna M Luda @KawaZbozowa
323 Followers 656 Following #Immunologist in love with #metabolism & postdoc in #LabSakamotoGlobal Translational .. @GTM_ASP
282 Followers 2K Following GTM is a quarterly journal that focuses on medicine, biological sciences, and biomaterials engineering.Sara Frangos @FrangosSara
142 Followers 316 Following PhD candidate | Human Health and Nutritional Sciences | University of GuelphProf. Toshi Yokota Ph.. @ToshifumiYokota
5K Followers 5K Following Garrett Cumming @MD_Canada Chair&Prof #Antisense #RNA #CRISPR #RareDiseases #Muscle #Bone #Neurology Trained @UTokyo_News @NCNP_pr @ImperialMed @ChildrensNatlAkava @AkavaTech
20K Followers 18K Following Silicon Valley technology consultancy shipping Innovative Products & Cloud-Native Solutions for Fortune 500 enterprises & hyper-growth start-upsTheFutureEconomy.ca @FuturEconomy
43K Followers 15K Following The best in Canadian thought leadership: insights on Canada’s future economy. Subscribe for exclusive content: https://t.co/L09Df0xTn0Anne-Raphaëlle Audou.. @audouin_anne
27K Followers 20K Following Chief Executive Officer @NukikCorp @KivalliqLink. 🇨🇦JPAC member @CECweb. 🌎 Reconciliation | Renewables | Climate action | Sustainability 🌱 Personal account.Emily Day @EmDay4
251 Followers 252 Following Postdoctoral Fellow at Trinity College Dublin. McMaster University Alumni.Stuart Phillips (he/h.. @mackinprof
54K Followers 5K Following Dad, Husband, Distinguished Univ Professor, tier 1 @CRC_CRC, @McMasterU; opinions mine. Scholar: https://t.co/9FZmrkltUw. Linktree: https://t.co/6w6NWx9M6p@MacMODR @MacMODR
662 Followers 192 Following McMaster's Centre for Metabolism, Obesity & Diabetes Research translates world leading basic science into clinical practice to improve metabolic disease.Kei Sakamoto @Kei__Sakamoto
1K Followers 194 Following Professor Univ. of Copenhagen, Vice Director Novo Nordisk Foundation Center for Basic Metabolic Research, Metabolic Signaling, glucose metabolism, AMPKDaniel J Drucker @DanielJDrucker
29K Followers 1K Following A clinician scientist at LTRI @sinaihealth @uoft @uoftmedicine who studies peptide hormones, GLP-1, diabetes, obesity and the gut endocrine system 🇨🇦🇮🇱Greg_Steinberg @DrGregSteinberg
845 Followers 66 Following Professor of Medicine at McMaster University studying metabolism. Co-Director of @MacMODR.Craig A. Goodman @CraigAGoodman1
3K Followers 531 Following Senior Scientist that investigates the molecular mechanisms that regulate skeletal muscle mass and function in health and in various disease statesTanner Stokes, Ph.D. @tjstokes5
428 Followers 604 Following Ph.D. in Kinesiology from McMaster University | Interested in skeletal muscle adaptation in response to exercise and inactivity.Oded Rechavi @OdedRechavi
140K Followers 1K Following Don't be fooled by the rocks that I got, I'm still Oded from the block. TED: https://t.co/rcOm9TSTf5 Huberman Lab Podcast: https://t.co/xZTNlx9nbiChristopher Perry PhD @ChrisPerryMito
3K Followers 989 Following Researcher/educator of muscle disorders and the metabolic basis of muscle fitness. Translating mitochondrial bioenergetics and redox biology to health/disease.Sakamoto Lab @LabSakamoto
2K Followers 472 Following We investigate molecular signaling mechanisms @metabolcenter ,UCPH. Interests in #AMPK #TFEB #SIK #Glycogen metabolic signaling. Tweets by @itsmedipsikhaMcMaster Health Scien.. @machealthsci
13K Followers 2K Following Official Twitter account of the Faculty of Health Sciences at McMaster University.Logan Townsend @LoganTownsend86
430 Followers 393 Following CIHR Post-Doc at McMaster @MacMODR. Liver & adipose metabolism in health and obesity. Flames, Chiefs, and Mavericks fan.Morgan Fullerton @Immunometabolab
1K Followers 640 Following I'm a Professor at the University of Ottawa. The lab studies the links between metabolism and immunity. I never match my socks.Nathan Hodson @nathanhodson5
747 Followers 877 Following Lecturer in Musculoskeletal Physiology - Manchester Metropolitan University - Interested in the mechanisms underpinning skeletal muscle hypertrophy/atrophy.PHRI.ca Population He.. @PHRIresearch
5K Followers 5K Following Birthplace of 9 most measurable modifiable risk factors for #heartdisease #stroke @McMasterU @hamhealthsci ACT on #clinicaltrials Newsletter: https://t.co/mpqGNzFps8Michael Riddell, PhD @MCRiddell1
3K Followers 1K Following Full Professor, Senior Scientist, Physiologist, and Diabetes Agent of Change- York University, Toronto CanadaDavid J Glass MD @davidjglassMD
5K Followers 3K Following book: Experimental Design for Biologists. Journal: Skeletal Muscle. Focus areas: Aging; Muscle. Works for a biotech company; views are mine.Michael Wong @aMichaelWong
881 Followers 511 Following Company builder passionate about transforming human & planetary health. Venture Creation & Business Development @FlagshipPioneer. Placental biologist. 🇨🇦Alex Green @AlexEGreen
277 Followers 666 Following MSc, PhD - PDF at uOttawa in Muscle, Metabolism and Mito Views are my own https://t.co/1Cm4PiU0ml https://t.co/vnSUPLuvpnBruce Booth @LifeSciVC
50K Followers 730 Following Early stage biotech VC. Recovering scientist. Opinions expressed are solely my own and do not express the views or opinions of Atlas Venture.Corey A Scipione @CoreyScipione
401 Followers 602 Following Postdoctoral Fellow @UHN + @UofT : #biochemist, #atherosclerosis, #endothelial- #myeloid biology, #immunology, #lipoproteins, #cardiovascular & #transcriptomicsMadison Bolger-Munro @mbolgermunro
243 Followers 442 Following Venture Associate @ Pre-Amp @amplitudeVC @ISTAustria & @UBCMicroImmuno alum she/her | 🔬🎿 🚴🏻♀️ 🇨🇦Manni Mohyuddin @ManniMD1
12K Followers 491 Following Cancer doctor with interest in myeloma, supportive care, end of life, cost-effective/evidence-based care and med-ed. Views own.Jean-Philippe Julien @jphilippejulien
607 Followers 99 FollowingJoAnne Foody, MD, FAC.. @FoodyMD
2K Followers 1K Following CMO Esperion, A Passion for Prevention, Champion for Women’s Health/ ❤️ Doc, #CVPrevention #WIC Opinions my ownMaria Jesus Gonzalez .. @ChusaGzlzRellan
746 Followers 2K Following PhD at Rubén Nogueiras lab 🇪🇸 Now Postdoctoral Fellow at Mount Sinai/LTRI, DanielDrucker lab 🇨🇦. Interested in endocrinology and metabolism. MSCA fellow🇪🇺Wilson (Yuqin Wu) @Wilson79078233
563 Followers 4K Following PhD candidate at Monash BDI, study in Glucagon signalling in metabolic control (supervised by Dr Adam Rose, the head of Nutrient Metabolism and Signalling lab)Stanislovas S. Jankau.. @SsJankauskas
2K Followers 5K Following Postdoc at @EinsteinMed. Mitochondria, aging, diabetes, CVD and CKD.🔬Confocal microscopy pro. 📷 as a hobby.iScience journal @iScience_CP
9K Followers 2K Following iScience is the interdisciplinary journal from Cell Press publishing across life, physical, earth and health sciences.Tyler Smith @TKT_Smith
92 Followers 113 Following PhD candidate at uOttawa studying the links between lipid metabolism and immune signaling.Irena Rebalka @IrenaRebalka
6 Followers 1 FollowingEvotec @Evotec
4K Followers 138 Following A drug discovery & development solutions company with a global presence.Philots @Soccratees
28 Followers 13 Following In a world where you can be anything, Be kind. Own the thought let AI tweet. DM for removal. Images are AI generated.Dr. Alice Cheng @AliceYYCheng
4K Followers 505 Following Endocrinologist, Mississauga/Toronto. Diabetes nerd. She/her.Moiz Ali @moizali
66K Followers 781 Following Founder @ Native Deodorant. Newsletter: https://t.co/bWuzRKuCOk Investor in 50+ companies Email: [email protected]Novo Nordisk Foundati.. @ScienceCluster
2K Followers 819 Following An international hub for cross-pollination of ideas and collaborations between institutions, industry and disciplines through networking and events.christina saed @SaedChristina
213 Followers 747 Following PhD student, Faculty of Pharmacy and Pharmaceutical Sciences University of AlbertaAlexandra Steele @alexpaigesteele
17 Followers 33 Following McMaster University | investigating cell sources for cultivated meatScott Isaacs @scottisaacsmd
13K Followers 2K Following President-Elect @theaace, endocrinologist, obesity medicine, #MASLD, Emory Med School adjunct faculty. Posts are my own.Science Translational.. @ScienceTM
30K Followers 279 Following The mission of Science Translational Medicine (AAAS) is to promote human health by communicating leading research and policy in biomedicine.Ville de Montréal @MTL_Ville
197K Followers 505 Following Compte officiel de la Ville de Montréal. Consultez notre nétiquette : https://t.co/L6ENFxvFBc…Alice Man @aleyecem
68 Followers 99 Following MD-PhD student @McMasterU @PHRIresearch 👩🔬 Alum @UBC 👩🎓 (she/her)Andrew Pannu @andrewpannu
10K Followers 274 Following daily dose of biotech & healthcare commentary • founder • building software for the bioeconomy (we’re hiring software engineers!)Catherine Bellissimo @cat_bellissimo
294 Followers 395 Following Postdoctoral Fellow @ecgoligher| PhD @ChrisPerryMito @MHRC_YorkU| Muscle Physiology | Duchenne muscular dystrophy| Mitochondria| Respiratory Muscle | DiaphragmGraham P Holloway @HollowayMitoLab
390 Followers 111 Following Physiology lab at the University of Guelph.Allied.vc @AlliedVC
2K Followers 2K Following Western Canada’s largest angel syndicate, investing in early-stage tech startups across Canada & the USA. Pitch us, Invest, Scout👇Startupfest @startupfest
16K Followers 6K Following Canada's original startup event, for aspiring founders, ground-breaking innovators and veteran #entrepreneurs from around the world. July 12-14, 2024 | MontréalDr Anna Stenning @anna_stenning
2K Followers 4K Following She/they; music lover and nature enthusiast. Research Associate at Durham University; own views. Co-editor of Neurodiversity Studies.Francesca Keefe (she/.. @keefe_francesca
184 Followers 1K Following Senior Research Development OfficerKatarzyna M Luda @KawaZbozowa
323 Followers 656 Following #Immunologist in love with #metabolism & postdoc in #LabSakamotoSara Frangos @FrangosSara
142 Followers 316 Following PhD candidate | Human Health and Nutritional Sciences | University of GuelphKevin Tharp @Derpology
1K Followers 2K Following Ignorance driven researcher applying haute couture blockchain omics-seq-oscopy to understand cellular mechano-metabolic relationships in cancer and aging.John Speakman @JohnSpeakman4
11K Followers 566 Following Scientist working in China and the UK. Studies energy balance: esp #obesity and #ageing. Likes #photography #wildlifephotography. Co-EiC: @lifemetabolism2Prof. Toshi Yokota Ph.. @ToshifumiYokota
5K Followers 5K Following Garrett Cumming @MD_Canada Chair&Prof #Antisense #RNA #CRISPR #RareDiseases #Muscle #Bone #Neurology Trained @UTokyo_News @NCNP_pr @ImperialMed @ChildrensNatlAkava @AkavaTech
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4K Followers 490 Following We simplify getting dressed so you can get on with the more meaningful things. #DoMoreInDUERPatrick van der Zande @zande_patrick
31 Followers 202 Following Passionate about science, sports and music. Post-doc @ Wageningen University | immunometabolism | exercise immunology & physiologyCanadian Women's Cham.. @can_wcc
17K Followers 9K Following CanWCC advocates explicitly for diverse women-identified and non-binary entrepreneurs, founders, and business owners. Become a Member.👇TheFutureEconomy.ca @FuturEconomy
43K Followers 15K Following The best in Canadian thought leadership: insights on Canada’s future economy. Subscribe for exclusive content: https://t.co/L09Df0xTn0BlockFlo Digital @BlockFloDigital
11K Followers 10K Following Bespoke digital marketing solutions, from content creation to community growth for tech, blockchain & non profit clients. See testimonials on our website. 🔽Anne-Raphaëlle Audou.. @audouin_anne
27K Followers 20K Following Chief Executive Officer @NukikCorp @KivalliqLink. 🇨🇦JPAC member @CECweb. 🌎 Reconciliation | Renewables | Climate action | Sustainability 🌱 Personal account.STAT @statnews
165K Followers 5K Following Reporting from the frontiers of health & medicine. Sign up for any of our 10 free newsletters here: https://t.co/CBx3GZBv31Endpoints News @endpts
29K Followers 70 Following The biopharma world is here. Get the industry’s most comprehensive daily news reports at https://t.co/qpcDlbaOSxTimmerman Report @timmermanreport
7K Followers 4 Following Timmerman Report is an independent biotech publication. Subscribe today! https://t.co/0HEk9RZHMV…FierceBiotech @FierceBiotech
101K Followers 649 Following The dominant B2B news brand for biotech. Delivering news, revealing insights straight to your inbox.Thank you to ALL who have passed through my lab (CM, NDL, SAS, NM, CZ, SW, RAY, LAB, COD, KDM, JRCN, PG, TKTS, KGO, AC, MR, SS, SH, NA, RG, TA, HD, MI, LAC, REH, SC, AR, WH, MDG, VRG, MK, CM, ACB, TA, RG, CP) + amazing collaborators. Fully Completely a Professor as of today.
It took a while but my MASTERS project is finally published. Thanks @hazelltj for pushing it along for a decade. Differential changes in appetite hormones post-prandially based on menstrual cycle phase and oral contraceptive use sciencedirect.com/science/articl…
14 years ago the lab started working on adherent-invasive E. coli that are a disease modifier in Crohn’s disease. Dr. Cherrie Small was the rockstar who got things going. Got to bump into her at our BDC Engage event last week in her role as a Director @AstraZeneca
New photo of our fabulous group @Metabolcenter! 🥳
Lab representation at Metabolism Day! Posters by PhD students @shoreseashell & Maria and postdocs @FlorentinaNego3 & @KawaZbozowa #MD24
Our paper is now online! Here we investigate the direct effect of lipolysis on AMPK signaling in adipocytes. Using our real-time FRET sensor we show lipolysis genereates long-chain acyl-CoAs that are involved in allosteric activation of AMPK.#lipidtime rdcu.be/duWEg
Feeling grateful and honoured for being awarded the @swiss_muscle grant...another great opportunity for me to keep my science going...thanks to everyone that made this happen...science rocks 🤘
Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 - JAMA - Really happy to be one of the authors on this paper. Weight loss maintenance is a cornerstone, preventing complications of obesity. jamanetwork.com/journals/jama/…
Thrilled to share our story on the first rationally designed #covalent #HDAC inhibitor! YSR734 uses an SNAr-reactive electrophile to engage a noncatalytic nitrosylation site cysteine in #HDAC2, showing in vitro activity in AML & #DuchenneMuscularDystrophy! pubs.acs.org/doi/10.1021/ac…
All patients with type 2 diabetes should be screened for NAFLD/MASLD. medscape.com/viewarticle/99…
Wet day on the trails but Trusty Companion did not care. She also did not care about the 1437 ft of up and down vertical, however her person seemed to notice. 😅
Thrilled to share a preprint from my PhD work on memory B cell plasticity in allergy. The persistence of IgE immunity critically relies upon MBCs. In this work, we show that the reservoir of allergen-specific MBCs can be reprogrammed away from an IgE fate!
Pathogenic IgE-fated B cell memory retains functional plasticity biorxiv.org/cgi/content/sh… #biorxiv_immuno
Happy to share my promotion to Associate Professor of Physiology at Wayne State University @waynestate
Congrats to Dr. Emilio Mottillo who was recently notified he has been promoted to Associate Professor (Research) FTA in Physiology effective August 2024!
Convocation was so special! @michelleogrod @jenniferheisz @jennyswilliams @billybostad @MACleod_JC @NgsySean
It's always a pleasure to host the lab for our annual holiday party. Good company, good conversations, Secret Santa gift exchange, and amazing food from around the world! Thank you to this amazing team for the privilege of working with you. #TeamCoombes
Memories - Wade Harper @HarvardCellBio, Tim Harris & I co-founded Rheostat Biotech in 2017 (renamed Caraway Therapeutics). This week @Merck acquired Caraway #neurodegeneration #lysysome portfolio - so proud. Congrats to M. Moran&team for this success👍🫶 longevity.technology/news/merck-bol…
🎓EDITOR'S CHOICE🎓 @xhutid, @Mats_I_Nilsson, @katherine_manta, Mark A. Tarnopolsky and Joshua P. Nederveen (@machealthsci) and show how circulating exosome-like vesicle and skeletal muscle microRNAs are altered with age and resistance training! 📜buff.ly/3SV5wWX
Congratulations to Mark Crowther, chair and professor @MacDeptMed, on being conferred the title of Distinguished University Professor from @McMasterU. Learn more about Crowther’s work and its impact 👇 ow.ly/F16t50Q9UzY
AMR problems are being solved here.
Researchers at @McMasterU are applying diverse strategies to combat AMR. From AI-guided drug discovery and bioinformatics to chemical biology, genomics, and so much more, we're driving toward new solutions to resistance. #WAAW2023 💊🦠🔬