GoggleDocs @GoggleDocs
🥽🩺Docs/nurses/pharmacists from U.K. Talking CardioRenoMetabolic & more Catch us on YouTube https://t.co/VSFSwEDXDD |Educate, Motivate, Activate! London, England Joined October 2020-
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GoggleDocs retweeted
Equity in access-based on colour of your skin- to technology, medicine and all interventions in #Diabetes care is a must And it’s as complicated as we make it Look forward to the @diabetes_africa meeting in November The work and progress must and will continue It is…
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#HISTORI Trial🧠💉 Semaglutide in Schizophrenia, Prediabetes & Obesity 🔸30-week RCT (n=154, Denmark) in antipsychotic-treated patients: ⤵️HbA1c 0.46% 🩸81% 🎯normoglycaemia (<5.7%) vs 19% placebo ⤵️Weight 9.2 kg ⤴️Physical QoL 😊 No worsening of psychiatric symptoms ⚠️ GI…
GoggleDocs retweeted
‼️‼️Draft new NG28 is now out! ‼️‼️ We finally have better access To GLP1s! 🥳 ▶️now groups split into subsets (frailty/HF/EOT2D etc) ▶️talks about NOT stopping meds once A1c is good if not having hypos 🔗 nice.org.uk/guidance/gid-n…
GoggleDocs retweeted
And.. the next episode of 'Kar-Mic' 😀 "Musings with Misra" A chat with one of the brightest stars of the #Diabetes world @ShivaniM_KC Chatting about leading ground-breaking research around '#T2D in the Young'; 'Precision Medicine', being a role model, and talking about the…
GoggleDocs retweeted
❗️Teplizumab approved by @MHRAgovuk ❗️ Great news - esp after seeing all the hard work go into this firsthand! ➡️First ever immunotherapy in UK approved for T1D ➡️ delay the onset of Stage 3 T1D in adults & children 8yrs & older with Stage 2 T1D gov.uk/government/new…
GoggleDocs retweeted
🧠 Sleep & Health 📊 Study in 88,461 UK Biobank participants 🧬 Key Findings (6.8 years follow-up): 172 diseases linked to poor sleep 🧪 Inflammation markers mediated many links Sleep health = systemic health spj.science.org/doi/10.34133/h…
GoggleDocs retweeted
📊 DAPA-MI Trial Randomised to dapagliflozin or placebo 📉 Key Results 🔻 New-onset T2DM risk ↓ Greatest benefit in BMI ≥30 + in those with prediabetes ✅Dapagliflozin may prevent T2DM & lower heart failure symptom burden post-MI Now off patent😜 ahajournals.org/doi/10.1161/JA…
GoggleDocs retweeted
🚶♂️ Benefits of fast walking Walking briskly ≥15 min/day cut all-cause mortality by ~20%, vs only ~4% for >3h/day slow walking Benefits were strongest for heart-related deaths & in those with chronic illness. #PublicHealth #Walking ajpmonline.org/article/S0749-…
GoggleDocs retweeted
🧠💉 Potential neuroprotective & cerebrovascular benefits of GLP-1RAs, beyond glycaemic & weight control. 📉 Compared to other antidiabetic meds, semaglutide/tirzepatide users had: 🧠 ↓ Dementia risk ↓ Stroke risk ⚰️ ↓ All-cause mortality jamanetwork.com/journals/jaman…
GoggleDocs retweeted
Comprehensive review by @ShivaniM_KC Ethnic diversity in precision medicine: a reality or an aspiration?
GoggleDocs retweeted
Oh look what has come up 🙂 11 years ago... Via @TheKingsFund @swoolnough 'Integrated care #Diabetes" Before the national role @NHSEngland Before the world of #T1Diabetes Before the battle for #Technology @PHU_NHS @HIOWH_NHSFT working together across @HIOW_ICS ...set up…
GoggleDocs retweeted
📊 GLP-1 & SGLT2 in T2D: Discontinuation, Reinitiation & Switching Swedish registry data 🔄 Discontinuation GLP-1 RA: 24% at 1 yr, 39% at 3 yrs SGLT2i: 28% at 1 yr, 46% at 3 yrs 🔎 Despite high discontinuation, 70–80% remained on therapy long term link.springer.com/article/10.100…
❗️ATTAIN-1 topline results announced ❗️ investor.lilly.com/news-releases/… 🔹almost 60% achieving 10% weight loss (we’ve moved beyond the 5% target now😁) with higher dose 🔸-12.4% change body weight with higher dose - rivals many injectables 🔹small molecule oral tablet - could open up…
GoggleDocs retweeted
📉 What happens after stopping anti-obesity meds? Meta-analysis Significant weight regain begins 8 weeks after discontinuation Continuing through 20 weeks. 🔁 Regain most notable with GLP-1 RAs ⚠️ Need for long-term strategies beyond medication alone bmcmedicine.biomedcentral.com/articles/10.11…
GoggleDocs retweeted
📢 Obesity associated with risk of atrial fibrillation 🔍 10-year cohort of 392,000+ adults Obesity increased AF risk by 43%. ⚠️ Only ~27% of this was mediated by conditions like diabetes & hypertension 73% was a direct effect. 🧠 #Preventobesity dom-pubs.onlinelibrary.wiley.com/doi/full/10.11…
GoggleDocs retweeted
@mvaduganathan @GoggleDocs @brendonneuen @CMichaelGibson @skathire @ankeetbhatt @dranulala @ShelleyZieroth @BevTchangMD @JavedButler1 @djc795 sciencedirect.com/science/articl… Link to baseline characteristics and background 😁😇
❗️Tirzepatide meets primary and secondary outcomes in its CVOT (SURPASS-CVOT)❗️ 🔹A first for CVOTs - comparing to dulaglutide (established benefit) 🔸Statistical analysis allows for comparison to putative placebo 🔹1ry outcome HR 0.92 p=0.086 🔸2ndry outcome HR 0.84 0=0.002…
GoggleDocs retweeted
Wow, the game has changed! #SURPASSCVOT meets its primary & secondary endpoints in first *head-to-head* CV outcomes trial! Tirzepatide (dual GLP1/GIP agonist) vs Dulaglutide (GLP-1RA) including 16% lower risk of all cause mortality! investor.lilly.com/news-releases/…
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