John Zhong @John2Zh
Working on Inflammation, Imaging, Immunology buaa.edu.cn Stockholm, Sweden Joined June 2013-
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✅ Don't miss our #APLAR25 session about new #treatments for systemic #Lupus ⬇️ on 5 September 2025, from 16:55 pm to 18:10 pm 😁 It's going to be amazing session, together with Prs. Marta Mosca and Andrea Doria 👍
The separation of immunodeficiency and rheumatology is a relic of history in modern medicine. It is all immunology in the end - Excellent new reminder by Megan Cooper & Joshua Tobin @jhumimmunity rupress.org/jhi/article/1/…
The difference between doing a project and presenting it. An observation can lead to many avenues of explorations before focus turns to a specific discovery. Presenting it, in a talk / paper, follows inversely, with broad perspectives coming before & after the specific discovery.
#CRISPR is more than Cas9 ✂️ 🧬 @BeiselLab reveals a short tracrRNA from S. pyogenes is toxic in L. paracasei, even without Cas9, underscoring challenges of using CRISPR-Cas9 in non-native hosts. buff.ly/qWjkxdK
Dietary saturated fatty acids skew monocytes and macrophages in the lungs toward an inflammatory phenotype and exacerbate airway inflammation in mice, shows a study that decrypts the connection between diet and lung immune cell activation. @ScienceTM scim.ag/46bjnOQ
🩸 Iron deficiency occurs when the body does not have enough stored iron. Worldwide, about 2 billion people have #irondeficiency and 1.2 billion people have iron-deficiency #anemia. Learn more in this JAMA Patient Page: ja.ma/45X8gsG
✅ Check #EULAR #recommendations for a core #dataset to support clinical care and translational and observational research in systemic #lupus erythematosus 📥 DOWNLOAD LINK: ard.eular.org/action/showPdf…
What I love about interferons is their simplicity ;-) But seriously a great @CellCellPress new review of IFNs that are our 1st line of defense vs infections and critical for many inflammatory an autoimmune diseases. cell.com/cell/fulltext/…
DNA copy number variation is strongly buffered at the protein level. The buffering is much stronger than at the RNA level.
Aging Quiets Lupus UCSF researchers have found that epigentic changes in interferon genes over time may lead to lupus being less active as they age. buff.ly/aYDZSdP
New article by me! Cardiovascular disease mortality rates have declined by around three-quarters since 1950, but we rarely hear about it. I explore some of the reasons behind the decline.
Those of you who are eagle-eyed may realize that this is the reason Nature Methods is hiring a new editor with imaging/microscopy expertise! The job ad closes in 2 days, get your applications in! (The position is for NYC/JC or Shanghai/Beijing.) springernature.wd3.myworkdayjobs.com/SpringerNature…
Those of you who are eagle-eyed may realize that this is the reason Nature Methods is hiring a new editor with imaging/microscopy expertise! The job ad closes in 2 days, get your applications in! (The position is for NYC/JC or Shanghai/Beijing.) springernature.wd3.myworkdayjobs.com/SpringerNature…
Absolutely over the moon about this Focus issue on the future of bioimage analysis!!! (a short thread)
Absolutely over the moon about this Focus issue on the future of bioimage analysis!!! (a short thread)
Scientists have created a tool that manufactures working proteins directly on the surfaces of cells go.nature.com/4meNl9U
Data from the second human treated with a prime edited medicine: a 56-year-old male with chronic granulotamous disease (CGD) had his bone marrow prime edited to insert the missing GT in NCF1, restoring NADPH oxidase function in neutrophils (DHR positivity) several fold beyond the…
Therapeutic and strategic analysis of biopharma companies trading below cash: 60/106 negative EV companies with mc <$100M, compared to 7 companies with a market cap above $500M 39% of these companies were oncology-focused; over half were in either Ph I or II Source: Canaccord
Summary Table of the massive defunding of biomedical research in the United States nytimes.com/interactive/20…
"It’s not surprising that lifestyles with less exposure to pollution [and inflammaging] are linked to lower rates of chronic disease." Comment on the report on inflammaging in 4 different places nature.com/articles/s4358… nytimes.com/2025/06/30/wel…
high-throughput single-molecule platform to study DNA supercoiling effect on protein–DNA interactions academic.oup.com/nar/article/53…

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