Beisel Lab @BeiselLab
Synthetic Biology lab of Chase Beisel at @Helmholtz_HIRI. Lab logo designed by our own PhD student, Adini Arifah! helmholtz-hiri.de Würzburg, DE Joined February 2022-
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Excited to share our work published in @NatureBiotech! We uncover and characterize a unique and highly versatile ancestral form of CRISPR-Cas12a (ReChb)! A big thanks to the whole team. 🧬 nature.com/articles/s4158… #SynBioLab @CICbioGUNE @IgorTascon @BeiselLab @FUNDELA1
A new research briefing has just been published in @NatureBiotech, summarizing the latest paper from #HIRI's @BeiselLab in collaboration with @YleniaJabalera and Raúl Pérez Jiménez from @CICbioGUNE. Check it out! ⤵️
A new research briefing has just been published in @NatureBiotech, summarizing the latest paper from #HIRI's @BeiselLab in collaboration with @YleniaJabalera and Raúl Pérez Jiménez from @CICbioGUNE. Check it out! ⤵️
Happy to have been able to contribute to the implementation of this exciting new genome editing tool coming out of the Chase Biesel lab! @BeiselLab Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes biorxiv.org/content/10.110…
Exciting stuff happening in microbiome science! Check out Charlotte Kamm's Spotlight article on engineering bacteriophages to deliver gene editors.
Exciting stuff happening in microbiome science! Check out Charlotte Kamm's Spotlight article on engineering bacteriophages to deliver gene editors.
In my publishing my first Spotlight article era ✨️ @BeiselLab
In my publishing my first Spotlight article era ✨️ @BeiselLab
Check out the exciting work of @Chunlei_Jiao on the PUMA technology for the precise detection of RNA with DNA-cutting Cas12 nucleases
Check out the exciting work of @Chunlei_Jiao on the PUMA technology for the precise detection of RNA with DNA-cutting Cas12 nucleases
#CRISPRCas systems have become a plentiful source of technologies for molecular diagnostics. #HIRI’s @BeiselLab has now expanded this extensive toolbox. PUMA enables the detection of RNA with Cas12 nucleases, which naturally target DNA. 🧬🐈🧵 Read more: helmholtz-hiri.de/en/newsroom/ne…
Exciting advance addressing a long-standing challenge: efficiently transforming DNA! Congrats to Justin Vento on his new paper introducing IMPRINT. @Helmholtz_HIRI @ncstatecbe doi.org/10.1016/j.molc…
Our brilliant team member, @Chunlei_Jiao will start a new adventure with his own lab at NUS in Singapore next year! A huge congratulations to him on this achievement. #CRISPR #PostdocPositions #PhDPositions
Our brilliant team member, @Chunlei_Jiao will start a new adventure with his own lab at NUS in Singapore next year! A huge congratulations to him on this achievement. #CRISPR #PostdocPositions #PhDPositions
Job Alerts, thrilled to announce that I will join NUS in Singapore in July 2024! 2 Postdoc and 4 fully-funded PhD positions available. Join me in this beautiful and vibrant place for #CRISPR and beyond research! If interested, email me or DM. Please RT!!!
(1/2) 🚨 Check out @BeiselLab’s recent work in @NAR_Open reporting new Anti-CRISPR proteins. They were discovered in a bacterial #pathogen with two extensively self-targeting Type I #CRISPR-Cas systems, and the Acrs block #DNA degradation but not DNA binding.
(2/2) For those and many more intriguing findings, including unexpected homologs, see 👇academic.oup.com/nar/advance-ar…
Such as pleasure to host @BeiselLab as a #ChafferFellow @otago @microtago. An amazing tour de force talk today titled “#CRISPR: a bottomless well of discovery and innovation”
Having trouble with transforming your favorite bacteria with valuable genetic cargo? Try IMPRINT🙌🏻! A sophisticated TXTL-based pipeline developed by @JustinVento @BeiselLab Fun and long-lasting collaboration between @nathanguy14 @BeiselLab members! Grateful to be part of it☺️
Having trouble with transforming your favorite bacteria with valuable genetic cargo? Try IMPRINT🙌🏻! A sophisticated TXTL-based pipeline developed by @JustinVento @BeiselLab Fun and long-lasting collaboration between @nathanguy14 @BeiselLab members! Grateful to be part of it☺️
A cell-free transcription-translation pipeline for recreating methylation patterns boosts DNA transformation in bacteria biorxiv.org/cgi/content/sh… #bioRxiv
Listen up, #CRISPR Fan(zor)atics! ✂️🧬 In a new @MolecularCell spotlight, @BeiselLab's @copa_bio recaps @zhangf's recent remarkable discovery describing eukaryotic #RNA-guided DNA endonucleases, called Fanzors. Read more here: authors.elsevier.com/a/1hjJC_OylrlC…
#CRISPR arrays are a compact way for nature to encode #gRNAs, but their ability to acquire new spacers keeps them longer than necessary for CRISPR technologies. #HIRI's @BeiselLab now shows that CRISPR-Cas9 arrays can be shortened without compromising: doi.org/10.1080/154762…
Great way to round out @crispr2023 #crispr with the conference dinner at the Wurzburg Residence!
Did you enjoy @crispr2023 or want to come to the next one! The #crispr conference will be in @Christchurch_NZ organised by @PeterFineran, @dsashital @gavinjknott and @drbridgetwatson. Check out the website crispr2025.org
Our postdoc @Chunlei_Jiao presented his recent findings at #CRISPR2023 today. If you have the chance also look at posters number 41, 43, and 48 from other lab members @katwandu @AngelaMigur @Okrety_MD
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