Joshua Modell @jwmodell
Assistant Professor of Molecular Biology and Genetics @ Johns Hopkins School of Medicine modelllab.com Baltimore, MD Joined September 2014-
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Connor's paper is out in Science! Thanks to all the present and former lab members for making this possible. If you are interested in the mechanisms behind stress induced endocycling or the role of CDK4/6 in maintaining G2 arrest, check it out: science.org/doi/10.1126/sc…
Led by @jakob_tr and @quiles_nuria, with @lasa_lab, we show that prophages utilise noncontiguous operons to balance immunity and autoimmunity. Our results underscore the essential fine regulation of these processes for prophages' life cycle development. nature.com/articles/s4156…
Really beautiful work describing the gatekeepers of phage nuclei!
The phiKZ jumbo phages build a protein based nucleus to protect their DNA(!), but what do they do before the nucleus is built? Led by outstanding post-doc @MozumdarDeepto, here we identify host and phage proteins in an immediate early phage lipid vesicle. biorxiv.org/content/10.110…
Our paper on functional discovery of protein degradation and stabilization effectors with proteome-scale induced proximity screens is out in its final version! 1/ nature.com/articles/s4158… rdcu.be/dBUju
Ever wonder why drug-resistant Mycobacterium tuberculosis is less fit than drug-susceptible Mtb? And how the bacterium can evolve to compensate for that cost?
Anything we can do, nature can do better🎵. Except maybe prime editing, but still.
Anything we can do, nature can do better🎵. Except maybe prime editing, but still.
Big update: we're hiring a new lab manager!! Come join a fantastic group of scientists in the @SternbergLab at Columbia University, in the heart of New York City, and contribute to cutting-edge CRISPR and genome engineering research. Please re-post and DM me with your interest
Check out our new paper showing how CRISPR-Cas9 systems fight back against phages with anti-CRISPR proteins!
Check out our new paper showing how CRISPR-Cas9 systems fight back against phages with anti-CRISPR proteins!
Thanks so much, very excited to join the Infectious Diseases community at JHMI!
My lab has several post-doc opportunities working in the RNA therapeutics space. Please apply and share! Thanks!
Just when you though transposons were capable of behaving selflessly… more great work from the Sternberg lab!
Just when you though transposons were capable of behaving selflessly… more great work from the Sternberg lab! https://t.co/rv7ZyhhHai
Hey folks, my very supportive department is looking for Assistant Professors! It is a broad search as we value diversity in both applicants and their research, so as long as you love mechanisms and molecules, please apply here apply.interfolio.com/129881! @JohnsHopkinsMBG
prokaryotic histones and CRISPR in the same paper!
prokaryotic histones and CRISPR in the same paper!
Congrats to the Sheltzer lab and Johns Hopkins’ own @vishruth_girish!
Congrats to the Sheltzer lab and Johns Hopkins’ own @vishruth_girish!
Viral cas genes? Broad-spectrum activity?? Congrats everyone on this thrilling plot twist!
Viral cas genes? Broad-spectrum activity?? Congrats everyone on this thrilling plot twist!
Kate and @reworkman0 went all out repping @JohnsHopkins today 🌟 @DavisLabJHU @jwmodell
Kate and @reworkman0 went all out repping @JohnsHopkins today 🌟 @DavisLabJHU @jwmodell
Erin Goley @goleylab
8K Followers 2K Following In my lab @johnshopkins, we like watching small things grow, divide, organize, and respond. @goleylab on bsky. She/her. 👩🔬👩👩👧👦🏳️🌈🧶🥃Marraffini Lab @MarraffiniLab
2K Followers 39 Following News from the Marraffini Lab @RockefellerUnivAude Bernheim @AudeBer
5K Followers 799 Following Microbial immunity, genetics, genomics, evolution @institutpasteur. Group leader @Mdmlab_paris Activist for more inclusive sciencesDenis Wirtz @deniswirtz
39K Followers 8K Following VP for Research @JohnsHopkins, T.H. Smoot Professor @HopkinsEngineer & @HopkinsMedicine, Co-founder @INBT_JHU, Lab: https://t.co/9OtmgB6InU Tweets are my own.Harmit S. Malik @HarmitMalik
44K Followers 8K Following Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results). @HutchBasicSci @fredhutch @HHMINEWS He/himalex meeske @alexjmeeske
1K Followers 753 Following Assistant Professor in @UW Dept. of Microbiology studying CRISPR-Cas functions in bacteriaAlejandra @alejandraaaaa_r
907 Followers 805 Following Ph.D. candidate @BCMB_JHMI | interested in time-resolved cryo-EM | 🇲🇽 scientistAlexander Harms @AHarms485
8K Followers 5K Following Bacteriophages, dormant bacteria, and bacterial immunity. Assistant Professor of Molecular Phage Biology at ETH Zurich.Patrick Hsu @pdhsu
30K Followers 3K Following co-founder @ArcInstitute, @BerkeleyBioE professor | researcher & investor in genome editing, biotech, AI | 🇨🇦 @harvard @broadinstitute @editasmed, Fast GrantsJoe Bondy-Denomy @joeBondyDenomy
5K Followers 3K Following BLACK LIVES MATTER. Associate Prof. @UCSF, Dept. of Micro & Imm. Toronto and Waterloo alum. Acrigen Biosciences co-founder. he/him/hisGreen Lab @GreenLabJHMI
4K Followers 236 Following Ribosome is life. Tweets by grads/postdocs, approved (sometimes) by Rachel GreenAmanda Shilton @AKShilton
436 Followers 613 Following PhD candidate @RockefellerUniv in @MarraffiniLab studying Type III CRISPR. Always nostalgic for African thunderstorms & jacaranda blooms🇿🇼 she/herJack Bravo @jpkbravo
931 Followers 712 Following Incoming Assistant Professor at IST Austria | Currently postdoc at University of Texas at Austin | Studying nucleoprotein complexes one particle at a timeLiz Kellogg ❄️�.. @kellogg_liz
4K Followers 1K Following Assoc. Member @St Jude Structural Biology, Pew Biomed. Scholar 2021, Margaret Dayhoff Oakley Awardee 2023, Co-host of #ThePlungePodcast w/@mcianfro & @mimi1inhBrun Lab @BrunLabCaulo
6K Followers 2K Following Yves Brun's lab, Canada 150 Research Chair in Bacterial Cell Biology. Bacteria and cool stuff they do and let us observe. @[email protected]Wiedenheft Lab @WiedenheftLab
592 Followers 175 Following News & views from Wiedenheft lab at Montana State University @montanastate | Account is managed by lab members.Nicole Marino @Nicole_D_Marino
963 Followers 339 Following Assistant professor at UPenn studying phage, bacteria, and all things anti-CRISPR.Dezmond Josef Cole @DezmondCole
1K Followers 1K Following PhD Candidate @GoleyLab @BCMB_JHMI | Bacterial Cell Biology 🔬 | Science x Society | 🏳️🌈Adair Borges @AdairLBorges
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224 Followers 3K Following Research Coordinator Department of Neurology, AIIMS New Delhi IndiaNasarout @nasarout91380
0 Followers 141 FollowingNancySusan @pG0Y5cC2Y70yr6x
0 Followers 369 FollowingJarin Tasnim @Jarin_Tasnim71
54 Followers 1K Following Wanderlust, Creative and Curious👀 #PhD student of Molecular Biology #CancerBiologyResearchAmany Alanany @AmanyAlanany
125 Followers 260 Following BSc in pharmacy •MSc in chemistry •Alumnus @ Hynes lab, McMasterU •Interested in phages👩🏻🔬 •Mama👨👩👦| 🇪🇬📍🇨🇦Alex (Chen Zhang) @Tsins361158385
315 Followers 1K Following A microbiology researcher, and believe they are in power dimensionally. A traveler from Asia (🇨🇳) to Europe (🇳🇱), and now in America (🇺🇸). Move Forward!Michael Reigh Guevarr.. @ReighGuevarra
288 Followers 4K Following BS Agriculture (Plant Pathology) graduate. Virology. Biotechnology. Vaccine Design. Also curious about Infectious Diseases and Cancer.Matthew Gates @Synchangel
973 Followers 5K Following Integrated Pest Management Specialist ┃ Insectus Optimus Maximus ┃ Founder of #Zenthanol Consulting and the Zenthanol #SciComm YouTube channelSTEVE @Steve_Emencheta
390 Followers 2K Following Academic | Phages mainly | A little other here and there |Rabia Fatima @rabiafatima_
98 Followers 150 Following Biochemistry PhD Candidate @McMasterU | Hynes lab | Studying bacteriophage-antibiotic synergyFélix Croteau @DNADoubleFelix
384 Followers 428 Following Biochemistry PhD from @McMasterU in the HynesLab studying Phages, CRISPR and natural competence. I like to build things. #QueerSTEM 🏳️🌈Alexander Hynes @APHage_
961 Followers 539 Following Father of Five. (he/him). Bacteriophages are amazing. Associate Professor, McMaster University.Lenora Wiggins @Le_nora_Wigg
7 Followers 38 Following Hey there, I'm Lenora Wiggins, a runway diva and fashion enthusiast. With an eye for elegance and style, I'm ready to rock the catwalk!Belinda Re @Be_linda_Re
24 Followers 85 Following Hello, I'm Belinda Re, a storyteller through the lens. Let's capture your special moments together, creating timeless memories.Héloïse Carion @CarionHeloise
131 Followers 262 Following Ph.D. student @RockefellerUniv | Formerly @UCSF @UCBerkeley | NSF GRFP FellowRousseau Geneviève @GeneMRousseau
15 Followers 33 FollowingMilan Gerovac @Milan_Gerovac
347 Followers 1K Following I farm very small life, cook in tiny volumes, and taste by fancy figures @Helmholtz_HIRI @Uni_WUEBen Adler @ben_a_adler
2K Followers 1K Following Postdoc @ Doudna Lab - UC-Berkeley | Bacteriophage engineering | CRISPR | Biotechnology | Microbiology | All Combinations Thereof | He/him. Opinions my own.Deepto Mozumdar @MozumdarDeepto
198 Followers 555 Following Postdoc @UCSF w/ @joeBondyDenomy & @AgardLab. PhD @Yale/@UCBerkeley @schepartzlab. Dabble in macromolecular machines, biochemistry, chembio & molecular biologyReese Caldwell @reesecald
142 Followers 310 Following PhD Student in @LiuGroup, @BroadInstitute | interested in genome editing and RNA | via @HSCRB '23, Flynn Lab @BCHStemCell, @Biohaven, @buenoscienceJesse Rowley @rowleyresearch
240 Followers 162 Following Scientist at the University of Utah studying #platelets, megakaryocytes, and gene expression. All views expressed are my own.Sowmyaa Shridhar @SowmyaaShridhar
1 Followers 56 FollowingJackson Lab @ USU @Jackson_Lab_USU
391 Followers 241 FollowingKevin H Chen @KHC_JHMI
101 Followers 124 Following PhD Candidate at Johns Hopkins School of Medicine Qiu Lab, Department of Physiology BCMB Graduate ProgramJ en ny @1996Jenny1128
12 Followers 26 FollowingShailab Shrestha @shailabshrestha
373 Followers 408 Following phd candidate @shenlabtufts studying how c. difficile cells divide and form spores | previously @wade_lab exploring salmonella CRISPRSuzanne H. DALLÉAC @DalleacSuzanne
3 Followers 23 FollowingNaile-Ila Koleci @naile_ila
51 Followers 340 FollowingDeepak Singh @Rush_toDeep
99 Followers 1K FollowingFoziyeh @FozyiehA
25 Followers 660 Followinglauren pope (she/her) @pope_lauren_
165 Followers 280 Following scientist at metagenomi ~ stanford bio PhD (ferroptosis, lipid metabolism) 🤓 JMU ‘17 dog mom 🏳️🌈🏳️🌈🏳️🌈Chunlei Jiao @Chunlei_Jiao
238 Followers 207 Following Incoming assistant professor in NUS; PhD & Postdoc @BeiselLab, @HIRI; Interested in discovering and engineering CRISPR and novel defense systems.ibrahim genel @ibrahimgenel_
3 Followers 497 FollowingDeepak Kumar @deepakdbg90
51 Followers 338 Following Research scholar at TAU, Israel, exploring the role of #CRISPR in microbial evolution, #Antifungal resistance, #Ph.D. student, #BihariFranklin Aviles-Vazqu.. @FranklinJ_
576 Followers 1K Following Biophysics Ph.D. student, Johns Hopkins University. Ha Lab 🔬 Guayama 🧙🏼♂️ UPR Ponce 🦁 / UPR Rio Piedras 🐓Mitchell O. Roth @MitchellORoth
61 Followers 183 Following FSU Molecular Biophysics @mobfsu Ph.D. Candidate - Protein engineering CRISPR-Cas9 https://t.co/iAweeFxm3T…Xiyan Wang( 王曦�.. @wangxiyan1
126 Followers 669 Following Former PhD student @DTUbioengineer🇩🇰, Bacterial secondary metabolites, Chitin degradation, Genetic manipulation. Now, Synthetic biology@ZJU🇨🇳。Next?Lena Keller @LenaMLKeller
194 Followers 446 Following PhD Student at @EWB_Lab @ETH 🧬🔬👩🔬 studying protein degradation pathways in mycobacteria 🧪| trash-TV enthusiast 🏃🏻♀️🧗♀️🏳️🌈 (she/her)Daniel Plaza Sáez @DPlazaSaez
784 Followers 2K Following Passionate Microbiologist 🦠🔬 | PhD @Cambridge_Uni | ex member Molecular Microbiology at @CamBiochem | Enthusiastic drummer 🥁 and keyboardist 🎹Luuk Loeff @l_loeff
651 Followers 514 Following Postdoc @ Jinek lab | Structural biology | Single-molecule Biophysics | Host-Defence | Joo lab alumni | #LINO23 alumniChristian F. Baca @ChristianF_Baca
183 Followers 228 Following PhD Candidate in the @MarraffiniLab at @RockefellerUniv and @TPCB_NYC. @UCirvine alumnusEmdad Ullah @EmdadSami
330 Followers 3K Following Ex-Cadet, BS (Biochemistry) & MS (#compchem) @ University of Dhaka (2013-19), past: @IRCMS_KU @icddr_b @msstate @caretutors. Looking for a #PhD in #compchemSankalp Padhi @SankalpPadhi1
142 Followers 657 Following Conference Secretary at USG | STAPH-2024 Virtual Conference | https://t.co/QNFGvT9pyDCharlotte Kamm @LK7606531793786
26 Followers 86 Following PhD student @BeiselLab. Currently trying to figure out how to repurpose DNA modifying proteins as gene editors. Alternatively, probably knitting.Erin Goley @goleylab
8K Followers 2K Following In my lab @johnshopkins, we like watching small things grow, divide, organize, and respond. @goleylab on bsky. She/her. 👩🔬👩👩👧👦🏳️🌈🧶🥃David R. Liu @davidrliu
64K Followers 59 Following Professor at Harvard, Broad Institute, & HHMI. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1Marraffini Lab @MarraffiniLab
2K Followers 39 Following News from the Marraffini Lab @RockefellerUnivAude Bernheim @AudeBer
5K Followers 799 Following Microbial immunity, genetics, genomics, evolution @institutpasteur. Group leader @Mdmlab_paris Activist for more inclusive sciencesHarmit S. Malik @HarmitMalik
44K Followers 8K Following Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results). @HutchBasicSci @fredhutch @HHMINEWS He/himDoudna Lab @doudna_lab
72K Followers 88 Following News from Jennifer Doudna's lab at @UCBerkeley @igisci. Tweets from lab members and not Jennifer Doudna unless signed JD. Tweets represent personal views only.alex meeske @alexjmeeske
1K Followers 753 Following Assistant Professor in @UW Dept. of Microbiology studying CRISPR-Cas functions in bacteriaJoe Bondy-Denomy @joeBondyDenomy
5K Followers 3K Following BLACK LIVES MATTER. Associate Prof. @UCSF, Dept. of Micro & Imm. Toronto and Waterloo alum. Acrigen Biosciences co-founder. he/him/hisGreen Lab @GreenLabJHMI
4K Followers 236 Following Ribosome is life. Tweets by grads/postdocs, approved (sometimes) by Rachel GreenMichael Eisen @mbeisen
77K Followers 15K Following I science & try to make science open. Tweets do not represent my employer's views, but are always correct. My conflicts of interest https://t.co/bZ7I9oSJe0.MDMLab @MDMlab_Paris
2K Followers 275 Following Molecular Diversity of Microbes Lab @institutpasteur // Focusing on bacterial immunity 🦠🧬🧫 // We ♥️ sharing our science with everyone // PI @AudeBerJack Bravo @jpkbravo
931 Followers 712 Following Incoming Assistant Professor at IST Austria | Currently postdoc at University of Texas at Austin | Studying nucleoprotein complexes one particle at a timeBrun Lab @BrunLabCaulo
6K Followers 2K Following Yves Brun's lab, Canada 150 Research Chair in Bacterial Cell Biology. Bacteria and cool stuff they do and let us observe. @[email protected]Eduardo Rocha @epcrocha
3K Followers 518 Following Evolution, microbiology, genomics, bioinformatics. Opinions are mine (and they may change).Wiedenheft Lab @WiedenheftLab
592 Followers 175 Following News & views from Wiedenheft lab at Montana State University @montanastate | Account is managed by lab members.Nicole Marino @Nicole_D_Marino
963 Followers 339 Following Assistant professor at UPenn studying phage, bacteria, and all things anti-CRISPR.Adair Borges @AdairLBorges
2K Followers 2K Following Scientist @ArcadiaScience 🧬✨| Former @UCBerkeley Miller Fellow @BanfieldLab | PhD @joeBondyDenomy lab @UCSF | She/Her | #LGBTQSTEM 🏳️🌈Arjun Raj @arjunrajlab
25K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12Jordan Barrows, Ph.D... @jordanmbarrows
691 Followers 1K Following Post-doc in @LaskerKeren lab @scrippsresearch | Former student in @goleylab | Love learning about bacteria, cool imaging techniques, and teaching | he/him/his |Alexander Hynes @APHage_
961 Followers 539 Following Father of Five. (he/him). Bacteriophages are amazing. Associate Professor, McMaster University.Rob Lavigne @RobLavigne1
5K Followers 2K Following All things bacteria, phage and other viruses. Biology to biotechnology. I actually enjoy teaching too! Hobbies? what are those?Heran Darwin, PhD @HeranDarwin
3K Followers 534 Following Professor of Microbiology. Views my own. #Tuberculosis @heran.bsky.socialAnders Sejr Hansen @Anders_S_Hansen
4K Followers 2K Following Associate Professor @MITdeptofBE : https://t.co/uy48t7k949 Interested in understanding the relationship between 3D genome structure and functionMike Piacentino @MikePiacentino
1K Followers 1K Following Assistant Professor, Dept of Cell Biology @HopkinsMedicine. Lipids and membranes in neural crest development. He/him. 🏳️🌈🔬Vishruth Girish @vishruth_girish
56 Followers 89 Following Lawnguylander, labrat, and mixologist. Not necessarily in that order. MD/PhD student studying cancer @HopkinsMedicine. Formerly @YaleMed @CSHL @StonybrookU.Andrew Santiago-Frang.. @SantiagoFrangos
2K Followers 1K Following Asst Prof @Penn. CRISPR Biology & Applications | Biochemist & CryoEM | #NIHMOSAIC K99/R00 + @BWFUND PDEP Fellow. View Mine.Kristina Jonas @krijonas
680 Followers 260 Following Associate Professor at Stockholm University. SciLifeLab group leader.Sharma Lab @SharmaLab1
1K Followers 281 Following Our lab @Uni_WUE focuses on gene regulation & virulence control in H. pylori and C. jejuni. Tweets by Cynthia (-CS) or the Sharma Lab (-Lab). All views our own.Jackson Lab @ USU @Jackson_Lab_USU
391 Followers 241 FollowingFrançois Rousset @FrancoisRousset
1K Followers 679 Following Bacterial genomics and phage-bacteria interactions🦠 Postdoc @SorekLab @WeizmannScience PhD from @dbikard @InstitutPasteurClint Smith @ClintSmithIII
399K Followers 2K Following Writer, @TheAtlantic. Author of Counting Descent, How the Word Is Passed, and Above Ground.PFF NE Patriots @PFF_Patriots
27K Followers 320 Following #Patriots grades, statistics and analysis from PFF | @PFF -- Contact: [email protected]Beisel Lab @BeiselLab
593 Followers 89 Following Synthetic Biology lab of Chase Beisel at @Helmholtz_HIRI. Lab logo designed by our own PhD student, Adini Arifah!Rebecca Heald @rebeccaheald
986 Followers 479 FollowingNathan Archer @ArcherLab
268 Followers 219 Following Asst. Prof. of Dermatology @HopkinsMedicine. We study immune responses during skin infections and inflammatory diseases to develop novel immunotherapiesDaan C. Swarts @DCSwarts
1K Followers 637 Following Group leader at Wageningen University & Research, NL | Prokaryotic immune systems | Views are my ownMartin Jinek @MartinJinek
4K Followers 347 Following Biochemist, structural biologist, CRISPR enthusiastSylvain Moineau @smoineau
1K Followers 310 Following Professeur, département de biochimie, microbiologie et bio-informatique, Université Laval, Québec, Canada https://t.co/UVdKZoXpEbAdi Millman @AdiMillman
1K Followers 700 Following Postdoctoral Fellow at the Laub Lab @MITBiology | PhD @SorekLab @WeizmannScienceCRISPR2025 @crisprmeeting
2K Followers 90 Following Official account of the annual CRISPR meeting. Join us in New Zealand for CRISPR 2025!Alaina Macaulay @AlainaMacaulay
1K Followers 802 Following Sr. Director for Inclusion & Strategic Engagement @UMassAmherst | Washed Up NCAA DI 🏐 | Wifey @DrCDTMacaulay | Mami 👩🏽🦱🧒🏽👶🏽🐾 | MKE is 🏠 | twts my ownDimitra Technology @dimltratech
13K Followers 2 Following Data driven farming. Increase yield. Reduce cost. Mitigate risk.Rajini Rao @madamscientist
8K Followers 2K Following Professor and Director of @CMM_JHU at Johns Hopkins. Ion transporter aficionado, experimental cook, advocate for #STEMWomen. Mastodon: @[email protected]Rafa Pinilla-Redondo @rafapinilla92
3K Followers 650 Following Asst. Prof. at @microUCPH, Copenhagen University. Excited about plasmids, phages, and bacterial immunity!👨🔬🔬Philipp Andesner @pehaielipepe2
52 Followers 268 FollowingSarah Voss @S_Voss1
84 Followers 163 Following @BCMB_JHMI Ph.D. Candidate in the Modell lab NSF GRFP Fellow Studying Bacterial Defense Systems Lover of yoga and hair dyeNessa Moran @feedhimlove
80 Followers 169 FollowingJulie Messersmith @JMessersmith_JH
3K Followers 2K Following @JohnsHopkins. Inspired by researchers tackling big problems. Any problem, really.Kayarash Karimian @Kayarash_
120 Followers 384 Following Biotech | Company Creation | VC | Former student in @CWGreider's lab studying how cells control their telomere length. @HopkinsMedicineJames Lynch @JamusLynch
1K Followers 2K Following Daylight Public Affairs. Strategy, Research, Communications. Alum of @kamalaharris, @jerrybrowngov, @barackobama / @thedemocrats, @jeffmerkley, etc. He/HimChris Dempsey @cdempc
9K Followers 4K Following Partner with @JeffSpeckFAICP at Speck Dempsey. We build walkable places. Co-founder @NoBosOlympics. Fmr. Assistant Secretary at @MassDot + Director of @T4Mass.Victora Lab @victora_lab
5K Followers 612 Following Laboratory of Lymphocyte Dynamics at @RockefellerUniv. Opinions are Gabriel’s own. @victora.bsky.socialSam Novey @noveyator
2K Followers 3K FollowingJared Schrader @schraderlab
873 Followers 955 Following Assoc. Prof. at WSU in Detroit. Enjoy all things related to RNA, RNPs, and biomolecular condensates.W. Marcus Lambert, Ph.. @marcus_phd
2K Followers 1K Following Assoc VP of Research @SunyDownstate | Assoc Prof @DownstateSPH | Advancing #HealthEquity and #DEIMolecular Biology and.. @JohnsHopkinsMBG
1K Followers 795 Following The Department of Molecular Biology and Genetics is one of eight basic science departments in the Johns Hopkins University School of MedicineDr. Nicole De Nisco @NicoleDeNisco
1K Followers 453 Following Assistant Prof @ UT Dallas investigating clinically relevant host-microbe interactions of recurrent UTI; Science Educator; MIT Alum; Cat Enthusiast; VegetarianWenyan Jiang @jiang_wenyan
172 Followers 73 Following Assistant Professor, Systems Microbiology with CRISPR genomics and single-cell transcriptomics, Mount Sinai School of MedicinePascal Maguin @pmaguin
181 Followers 163 Following Sr Scientist at Regeneron Pharmaceutical - Former PhD student in the @MarraffiniLab.Nate Cohn @Nate_Cohn
471K Followers 1K Following chief political analyst, @nytimes. writing about elections, public opinion and demographics for @UpshotNYT. polling and needling. PNW expat.Connor's paper is out in Science! Thanks to all the present and former lab members for making this possible. If you are interested in the mechanisms behind stress induced endocycling or the role of CDK4/6 in maintaining G2 arrest, check it out: science.org/doi/10.1126/sc…
Congrats @amer_hossai1 for the great work on anti-phage DNA glycosylases!! Thanks to our collaborator Phoebe Rice, and also Sean Brady and Joshua Chappie. nature.com/articles/s4158…
Et de deux! @DNADoubleFelix presenting the spoils of his PhD - Warhammer, Phage-Planters, and DNA. Oh, and a Thesis, I suppose. A masterful defence, a wonderful external @jwmodell... and there goes the last of the lab's starting cohort. *sniff*.
🚨🫴Final PhD work is out 🧬 Cam1, a ligand-activated transmembrane pore, is associated with type III CRISPR systems and depolarises the host membrane during infection. Proud of @ChristianF_Baca 🫡and co-authors for doing the heavy lifting for a beautiful (I’m biased) story 🫴🚨
Excited to share my first work in the @MarraffiniLab, now online @Nature ! We show that type III CRISPR utilizes a transmembrane effector, which we call Cam1, to provide anti-phage immunity! Synopsis 🧵: nature.com/articles/s4158…
Excited to share my first work in the @MarraffiniLab, now online @Nature ! We show that type III CRISPR utilizes a transmembrane effector, which we call Cam1, to provide anti-phage immunity! Synopsis 🧵: nature.com/articles/s4158…
Ohhhhh y'all. @ChrisMahonePhD's paper took a minute, but the final *super impressive* version is officially published @JCellBiol. Check it out here rupress.org/jcb/article/22… 1/
Story time!! @ItsChrisMahone’s thesis work is out in pre-print form and I am SO EXCITED to share it w you. Here’s the scoop… 1/
💻🧫New preprint: How accurately can we predict diverse phage bacteria-interactions from their genomes only ? We created a matrix of >38k phage-bacteria interactions to find out (=> AUROC 86%) & used our predictions to recommend tailored phage cocktails. biorxiv.org/content/10.110…
We’re beyond excited to share the newest pre-print from the Sternberg Lab! You thought all bacterial transposons (aka IS elements) were simple? Think again…🤓1/6
Believe it or not, all discovered (3 of 3) cyclic nucleotide "sponge" proteins encoded by phage have two binding sites for inhibiting CBASS/Thoeris! New preprint from the lab together with outstanding collaborator Yue Feng and team. BDLab: Iana @femtokot and @ErinHuiting led!
Single phage proteins sequester TIR- and cGAS-generated signaling molecules biorxiv.org/cgi/content/sh… #biorxiv_micrbio
It's out! This paper on phage RNA-mediated activation of bacterial CBASS systems should activate your interest in reading it 🧪🦠🪐📑 @daltonbanh @camgroberts @MarraffiniLab nature.com/articles/s4158…
Great to have @andrewjvarble as visiting speaker at Cornell Microbiology @CornellMicrobio. The Peters lab took him out to lunch before sending him back to @UofR
@jwmodell lab and I are excited to celebrate #WorldPhageWeek this year with our new preprint, showing how CRISPR-Cas9 systems can respond to phage-encoded anti-CRISPRs and ultimately counterbalance Acr-phage infections! biorxiv.org/content/10.110…
Welcome to the ID Division @jwmodell, newly appointed joint faculty! Learn about his work on interactions between #bacteria, #CRISPR-Cas systems, & #bacteriophage using molecular bio, genetics, genomics, biochem & imaging @JohnsHopkinsMBG mbg.jhmi.edu/people/joshua-…
1/3 Excited to share our work published in @Nature! We uncover how phages inhibit CRISPR-Cas immunity via RNA anti-CRISPRs (𝗥𝗮𝗰𝗿𝘀)! nature.com/articles/s4158…
And just like that we have a preschooler on our hands. Pictured here (possibly) thinking deep thoughts about his favorite time of day (snack time) and his favorite book, Where The Wild Things Are!
Hope everyone had as great of a #phages2023 as I did. Awesome science, fantastic people, and a growing community of scholars that I am thrilled to be part of! Thanks again everyone!
Go Nick! @BCMB_JHMI @jwmodell
Nicholas Keith (Modell lab): prophages are hotspots for spacer acquisition and can “vaccinate” bacteria against future infections #Phages2023
New preprint! Simultaneous multi-site editing of individual genomes using retron arrays. We're trying to make it easier to make multiple, non-adjacent, precise mutations to a genome without long cycles of editing, isolating , and editing again. biorxiv.org/content/10.110…
5 years today @jwmodell !! ❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️
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Use the expertise of people at every level in and outside of systems to build structures, make decisions, learn, and adjust. Learn from CPRL alum @cleolacyhirsch's #leadership moves to spark progress at @BaltCitySchools, @GovWesMoore, @AmeriCorps. cprl.law.columbia.edu/news/making-li…