CRISPR MEMES @CrisprMemes
Nobel Prize-winning memes hypersaline lake metagenome Joined March 2021-
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being a bacterium wouldn't be all bad. for one, you'd probably have your own CRISPR system time.com/6226660/siddha…
in these unprecedented times, it's heartwarming to see people doing what really matters; abiding by arbitrary CRISPR naming conventions embopress.org/doi/full/10.15…
if you've also been here, this is the paper for you!!! super cool that less (guide RNA) = more (on-target) edits!
if you've also been here, this is the paper for you!!! super cool that less (guide RNA) = more (on-target) edits! https://t.co/46wA6oete9
it's a friendly & accessible resource, but HOLY HECK the conflation of cas9 as "everything CRISPR" really GRINDS MY GEARS
it's a friendly & accessible resource, but HOLY HECK the conflation of cas9 as "everything CRISPR" really GRINDS MY GEARS
adept alliteration assure authors ample attention
you CANNOT....STOP.....the CHOP
fool me once, shame on you. fool me twice, shame on inadequate spacer acquisition by Cas1-Cas2 (and ancillary) adaptation complexes
when you've already solved 15 Cas9 structures, and you do another one just to EVEN FURTHER refine the model of off-target activity
when you've already solved 15 Cas9 structures, and you do another one just to EVEN FURTHER refine the model of off-target activity https://t.co/QEUUUDFLzO
*CSI guy voice*: ENHANCE THAT CAS12A
when they're a 12 but they don't chop DNA 🤷🤷
when they're a 12 but they don't chop DNA 🤷🤷
...but i'm a creep, i'm a class 1 effector...
few years ago it was engineered cas12a, and cas9 a few years before that....
irreparable damage to this week's reading list, pls slow down @davidwtaylorjr and co....
a warm welcome to type V's weirdest new nuclease!! biorxiv.org/content/10.110…
stellar meme courtesy of @IngaTrails, and a merry #CRISPR2022 to those attending!!
yeah BUT we found ONE locus where it's ALMOST as good as SpCas9!!!!!
we're ALL trying to find the guy that BROKE this POOR PHOSPHATE BACKBONE
Nicole M. Gaudelli @NicoleGaudelli
5K Followers 269 Following EIR @GVteam, dreamer, inventor of ABE. Interested in genomic medicine and next-generation application of gene editing tools. Leonardo’s & Isabella’s Mom.
Fyodor Urnov @UrnovFyodor
15K Followers 533 Following Gene editor + Professor of Molecular Therapeutics @berkeleyMCB + Director of @igisci @danahercorp Beacon for CRISPR Cures.
Patrick Hsu @pdhsu
30K Followers 3K Following co-founder @ArcInstitute, @BerkeleyBioE professor | researcher & investor in genome editing, biotech, AI | 🇨🇦 @harvard @broadinstitute @editasmed, Fast Grants
Martin Jinek @MartinJinek
4K Followers 347 Following Biochemist, structural biologist, CRISPR enthusiast
Ben Kleinstiver @BKleinstiver
4K Followers 670 Following Associate Professor @CGM_MGH at @MGH_RI & @HarvardMed Genome editing / Protein eng. / Molecular medicine 🇨🇦🧬 Kayden-Lambert MGH Research Scholar '23-28
Omar Abudayyeh @omarabudayyeh
7K Followers 2K Following McGovern Fellow @mcgovernmit by way of @broadinstitute | @harvardmed |@MIT Molecular tool lab. Co-founder @Sherlock_bio & https://t.co/GnLoSlRvsZ & https://t.co/ElMMNGf8bL
Jonathan Gootenberg @jgooten
4K Followers 2K Following Pull apart the double helix like a wishbone || Ars longa, tweeta brevis
Liz Kellogg ❄️�.. @kellogg_liz
4K Followers 1K Following Assoc. Member @St Jude Structural Biology, Pew Biomed. Scholar 2021, Margaret Dayhoff Oakley Awardee 2023, Co-host of #ThePlungePodcast w/@mcianfro & @mimi1inh
Martin Pacesa @MartinPacesa
3K Followers 929 Following Structural biologist working on 🖥️ protein design and #CRISPR-Cas systems ✂️🧬 Avid weirdness connoisseur 🎩
John Evans @john_evans3
7K Followers 336 Following CEO, Beam Therapeutics. We are working on creating precision genetic medicines using base editing. (tweets are my own)
Joe Bondy-Denomy @joeBondyDenomy
5K Followers 3K Following BLACK LIVES MATTER. Associate Prof. @UCSF, Dept. of Micro & Imm. Toronto and Waterloo alum. Acrigen Biosciences co-founder. he/him/his
Niko McCarty 🧫 @NikoMcCarty
23K Followers 865 Following Writing and editing stories about scientific progress, especially in biology. Founding Editor @AsimovPress Head of Creative @AsimovBio
Daan C. Swarts @DCSwarts
1K Followers 637 Following Group leader at Wageningen University & Research, NL | Prokaryotic immune systems | Views are my own
Josh Tycko @JoshTycko
2K Followers 3K Following Postdoc at Harvard Med, Greenberg lab & BIDMC, Pollak lab aka DJ Fishing Expedition
Basem Al-Shayeb, Ph.D.. @themicrobeguy
3K Followers 581 Following Co-Founder @ Amber Bio ⌬ PhD from @Doudna_lab & BanfieldLab @UCBerkeley🌋🦠👨💻🧬⌬Science #ForbesUnder30 ⌬ formerly @NASAAmes, 🇪🇬🇺🇸 ⌬ #crispr #phage #borgs
Marson Lab @MarsonLab
8K Followers 4K Following News from Dr. Alex Marson's lab @UCSF & @GladstoneInst, focusing on advances in immunology, CRISPR & genomics. Tweets represent personal views only.
MichaelSchmitz @Michael__Sch
193 Followers 208 Following
Jack Bravo @jpkbravo
931 Followers 712 Following Incoming Assistant Professor at IST Austria | Currently postdoc at University of Texas at Austin | Studying nucleoprotein complexes one particle at a time
Janice Chen @janiceschen
4K Followers 419 Following Co-founder @mammothbiosci. PhD from @doudna_lab | @UCBerkeley MCB
Debojyoti Chakraborty @Debojyoti_C
3K Followers 415 Following Devoted to Nikhil Banerjee and a little bit of CRISPR -views personal-
TheraAdam @2k5MomGjqWQCy7
0 Followers 233 Following
Thara Antony @AntonyThara
129 Followers 787 Following Passionate about Molecular Biology, Epigenetics and DNA Replication Research
Lei Yang @LYang007
9 Followers 96 Following
Katrina @katrina86702547
32 Followers 251 Following
lifeisgood⚡️ @lifeisgoodBTC
663 Followers 568 Following 🇰🇷🇺🇸Bitcoiner. To be Sovereign Individual. Hammock Lover. npub18p45a746zd3hz3m0n94gu76cxvcszms2l2eqdq7jz3lauymje04svlmt9w
Sharon Allmon @sharon_allmon
0 Followers 14 Following
Golden Hind @goldenstartups
290 Followers 5K Following
Countagen @countagen
26 Followers 272 Following We pioneer gene editing analysis solutions that accelerate the validation workflow of gene editing research.
Paul Marganski @paulBIOgeek
58 Followers 193 Following I am interested in technology, biotech, finance, networking, business development, and anything interesting.
Gemma @GemmaValcarcelX
74 Followers 178 Following PhD student at @CarrerasIJC (Epigenetic control of haematopoiesis lab) #DNAmethylation #CRISPR
Cytosurge Inc. @cytosurge
612 Followers 1K Following Cytosurge enables next-generation biologic production and cell and gene therapy treatments, empowering people to live longer and healthier lives.
Jack Blank @Blank_Notions
157 Followers 290 Following Scientist | CRISPR Enthusiast | Passionate about all things Biotech | Inquisitive about AI |
laucha @lautimaffoni
113 Followers 154 Following La única lucha que se pierde es la que se abandona snapchat:lautioterom
Guosheng Gao @guosheng_g26264
8 Followers 59 Following
Athena Nicols @AthenaTzokas
0 Followers 10 Following
Dr. Maddie Ray @maddiehray
5K Followers 3K Following Scientist in genetic medicine. Cat Mom. She/Her. Views/Opinions/RTs are my own. 👩🏻🔬🏳️🌈
Geoby George @Geoby_G
1 Followers 25 Following
Ailín Arizmendi @AilinArizmendi
155 Followers 436 Following Recuerda que siempre, SIEMPRE, hay que ponerle una sonrisa a la vida!
mocha maid @mocha51825
0 Followers 2 Following
Jovita D Silva @JRD008
30 Followers 72 Following PhD student @John Curtin School of Medical Research, ANU. Working on some fun CRISPR Cas systems!!
Donato A. @donato_a_
175 Followers 620 Following company: “we plan to use an adaptive immune system from Streptococcus pyogenes to engineer the human genome” me: “not sure what those words mean but I’m all in”
Nick Manners-Bell @NickFMB
76 Followers 279 Following Student at King's College London, Bsc Biomedical Science
Ilaria Bonuzzi @IlariaBonuzzi
5 Followers 87 Following
Tina Tian @tinazytian
22 Followers 449 Following
Yashi Yyg @Yashi4350
5 Followers 28 Following
Science Sophie @science_sophie
643 Followers 880 Following There is always another experiment Post Doc @WEHI_research -Auto Inflammatory Inflammingo- Interferon Fan - JAK of all trades
Reid Brewer @ReidBrewer3
16 Followers 127 Following
Brigette Manohar @BrigetteManohar
77 Followers 228 Following @fiubiomed ‘20 | @berkeleymcb doctoral student @ the Wilson Lab 🧬🔬🧫 stay humble during your highs and lows Opinions are my own.
Vaisak Mohan @Vaisak_Mohan
12 Followers 110 Following
mschrauben @m_schrauben
0 Followers 53 Following
Kalin Mayberry @KalinMayberry
25 Followers 54 Following Dog Mom to Lady❤️😇, Memphis💙😇, Maggie💚😇, Mia💜, and Macy 💛 Lover of Research🧬, Animals🐾, Books📚, Music🎵, Football🏈, the Oxford comma, and Fridays 🙌
UFIFAS_IndianRiverREC @UFIFAS_IRREC
2K Followers 4K Following Agricultural and natural resources Research, education and Extension in the heart of the world's premier grapefruit production region
Antony_kigaru @Antony_kigaru
667 Followers 3K Following PhD scholar at Pan African University Institute for Basic Sciences Technology and Innovation Plant molecular biology, genome editing, plant tissue culture
Tautvydas @TautvydasKa
52 Followers 110 Following Researcher at Vilnius University @VU_LT | CRISPR-Cas | Genome editing | Transposons
Plant Genome Editing @GEd_Plants
945 Followers 1K Following Disseminating knowledge in Plant Genome Editing #Genome_engineering #CRISPR #PRIME_EDITING #BASE_EDITING #PLANTS
Sarah Rogers @sarahstorehouse
425 Followers 5K Following software engineering for bio and climate. @mit @google @facebook roles in synbio, infrastructure, and carbon capture
JUN-HUGN CHO @CHOJUNHUNG
70 Followers 559 Following
Astrid @MentaniAstrid
17 Followers 161 Following
Make People Better Co.. @MakePeople_Film
446 Followers 759 Following A documentary film that tells the inside story of the first genetically designed babies created in China. Make People Better Podcast is out now!
terllerice @terllerice
246 Followers 5K Following
David R. Liu @davidrliu
64K Followers 59 Following Professor at Harvard, Broad Institute, & HHMI. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1
Nicole M. Gaudelli @NicoleGaudelli
5K Followers 269 Following EIR @GVteam, dreamer, inventor of ABE. Interested in genomic medicine and next-generation application of gene editing tools. Leonardo’s & Isabella’s Mom.
Patrick Hsu @pdhsu
30K Followers 3K Following co-founder @ArcInstitute, @BerkeleyBioE professor | researcher & investor in genome editing, biotech, AI | 🇨🇦 @harvard @broadinstitute @editasmed, Fast Grants
Martin Jinek @MartinJinek
4K Followers 347 Following Biochemist, structural biologist, CRISPR enthusiast
Ben Kleinstiver @BKleinstiver
4K Followers 670 Following Associate Professor @CGM_MGH at @MGH_RI & @HarvardMed Genome editing / Protein eng. / Molecular medicine 🇨🇦🧬 Kayden-Lambert MGH Research Scholar '23-28
Jacob Corn @jcornlab
5K Followers 508 Following Genome editing, functional genomics, and cells figuring out how to eat themselves without dying. Professor of Genome Biology at ETH Zürich.
Wei Zhao @zhaoweiasu
4K Followers 98 Following Interested in 🧬 Gene Editing: BE & PE || Science Enthusiast || Not Financial Advice
Innovative Genomics I.. @igisci
16K Followers 944 Following Using genome engineering to solve humanity’s greatest problems in health, climate & sustainable agriculture. Partnership between @UCBerkeley and @UCSF. #CRISPR
Martin Pacesa @MartinPacesa
3K Followers 929 Following Structural biologist working on 🖥️ protein design and #CRISPR-Cas systems ✂️🧬 Avid weirdness connoisseur 🎩
Joe Bondy-Denomy @joeBondyDenomy
5K Followers 3K Following BLACK LIVES MATTER. Associate Prof. @UCSF, Dept. of Micro & Imm. Toronto and Waterloo alum. Acrigen Biosciences co-founder. he/him/his
Darrion Nguyen @lab_shenanigans
51K Followers 296 Following science content creator 🧬🔬, flaming homosexual™ 🥵🏳️🌈, biochemistry & theatre UT alum 🤘🏼, represented by @a3artistsagency
Daan C. Swarts @DCSwarts
1K Followers 637 Following Group leader at Wageningen University & Research, NL | Prokaryotic immune systems | Views are my own
Basem Al-Shayeb, Ph.D.. @themicrobeguy
3K Followers 581 Following Co-Founder @ Amber Bio ⌬ PhD from @Doudna_lab & BanfieldLab @UCBerkeley🌋🦠👨💻🧬⌬Science #ForbesUnder30 ⌬ formerly @NASAAmes, 🇪🇬🇺🇸 ⌬ #crispr #phage #borgs
Marson Lab @MarsonLab
8K Followers 4K Following News from Dr. Alex Marson's lab @UCSF & @GladstoneInst, focusing on advances in immunology, CRISPR & genomics. Tweets represent personal views only.
Marraffini Lab @MarraffiniLab
2K Followers 39 Following News from the Marraffini Lab @RockefellerUniv
CRISPR2025 @crisprmeeting
2K Followers 90 Following Official account of the annual CRISPR meeting. Join us in New Zealand for CRISPR 2025!
Jack Bravo @jpkbravo
931 Followers 712 Following Incoming Assistant Professor at IST Austria | Currently postdoc at University of Texas at Austin | Studying nucleoprotein complexes one particle at a time
Janice Chen @janiceschen
4K Followers 419 Following Co-founder @mammothbiosci. PhD from @doudna_lab | @UCBerkeley MCB
Malcolm White @mfwhite2
2K Followers 414 Following Professional: CRISPR, phage-host conflict, Archaea and molecular evolution. Personal: cat owner, kayaker, climate concern and our responsibilities as scientists
Best of Dying Twiter @bestofdyingtwit
109K Followers 3 Following Looking into it. Chief Looker: @jenntakahashi
Beisel Lab @BeiselLab
593 Followers 89 Following Synthetic Biology lab of Chase Beisel at @Helmholtz_HIRI. Lab logo designed by our own PhD student, Adini Arifah!
Cryptic Prophage (pha.. @crypticprophage
575 Followers 187 Following TAs 🛑 phages ('96), phages ➡️ persisters, E. c. CRISPR 🛑 cryptic prophages, indole=interkingdom signal, AI2 incr biofilm & TqsA exports (Prof. Thomas K. Wood)
Guillaume Levrier @g_levrier
930 Followers 1K Following Postdoc @_Nano_Bubbles / @cnrs / @umr_lisis | Policy implications of genome editing @sciencespo / @cevipof | French Web archives @laBnF / @DLwebBnF
Jackson Lab @ USU @Jackson_Lab_USU
391 Followers 241 Following
Long Lab Cheese Man (.. @ParafilmM
9K Followers 1 Following Stanning laboratory sealing film and spreading the word of The Purp! (no association with Bemis, Amcor, or the Swedish royal family)
Roland Calvert @roland_calvert
95 Followers 342 Following PhD student at Monash | Aspiring structural biologist and biochemist | he/him 🌈
Ben Adler @ben_a_adler
2K Followers 1K Following Postdoc @ Doudna Lab - UC-Berkeley | Bacteriophage engineering | CRISPR | Biotechnology | Microbiology | All Combinations Thereof | He/him. Opinions my own.
David S. Goodsell �.. @dsgoodsell
26K Followers 116 Following ~molecular art | molecular science~ free digital files of my paintings at RCSB PDB: https://t.co/gJwOxh1GXU…
Julia Galef @juliagalef
117K Followers 502 Following Author of THE SCOUT MINDSET and host of the Rationally Speaking podcast
Kai Kupferschmidt @kakape
150K Followers 2K Following @kakape.bsky.social science journalist. molecular biologist. curious. writer at @sciencemagazine part of @pandemiapodcast, all things #blue
Winston Yan @winstonxyan
1K Followers 493 Following Co-Founder https://t.co/u1aLTCtL4J, President https://t.co/kBAKlo33sB, #CRISPR wrangler. MD @HarvardMed, PhD w/ @zhangf @MIT, physics @Harvard. Enjoys Type II fun.
Small Things Consider.. @STCmicrobeblog
6K Followers 461 Following A blog that aims to share appreciation for the width & depth of microbial activities. 👉 @[email protected] 👉 @[email protected]
Stan Brouns @StanBrouns
1K Followers 141 Following CRISPR and bacteriophage researcher Delft University of Technology
SLIME MOLD TIME MOLD @mold_time
11K Followers 303 Following "If one does not expect it, one will not find out the unexpected; It is not to be tracked down and no path leads us to it." // https://t.co/YLVd6o5tdr
Aarit Ahuja @aarit_ahuja
9K Followers 2K Following Neuro PhD student at @BrownUniversity. Undergrad from @wesleyan_u. Co-founder of https://t.co/eBg7chsZVt. 🇮🇳 ➡️ 🇺🇸 . I mostly post memes on twitter
Soumya Kannan @soumya_kannan12
588 Followers 182 Following (she/her) Junior Fellow at Harvard Society of Fellows | current postdoc YEC lab PhD @MITdeptofBE Feng Zhang Lab @broadinstitute
Scott Alexander @slatestarcodex
138K Followers 30 Following I have a place where I say complicated things about philosophy and science. That place is my blog. This is where I make terrible puns.
Sketching Science @sketchscience
29K Followers 2K Following Science, Memes, Art, and Internet. Created by @neto_flames
Arash @Aye_Ba_Kolah
6 Followers 61 Following I'm among those who think life is boring without science!
lost grad student, ph.. @Drawrof1
6K Followers 5K Following my data runs wild and free as i have yet to gather it
Longreads @Longreads
286K Followers 10K Following Sharing and publishing the best longform stories since 2009. An @automattic publication and the sister site of @Atavist. @[email protected]
The Guardian Long Rea.. @gdnlongread
107K Followers 258 Following In-depth reporting, essays and profiles
Existential Comics (f.. @existentialcoms
419K Followers 171 Following A philosophy webcomic about the inevitable anguish of living a brief life in an absurd world. Also jokes. Follow me on bluesky: existentialcomics
Colin Jackson @Jackson_Lab
2K Followers 921 Following Protein Engineering and Evolution. Views my own.
Contamination Club @ContamClub
11K Followers 10 Following One of the greatest discoveries in microbiology came from contamination. Join the club and share yours here 🦠🧫 logo by @sylsyltong
Savage Lab @SavageCatsOnly
2K Followers 478 Following Compartmentalizing your metabolism, and y’know, CRISPR stuff. Account managed by grad students and postdocs 🤙 @UCBerkeley @berkeleyMCB @igisci @HHMINEWS
Evan Groover @evan_groover
974 Followers 2K Following Building CRISPR tools and techniques for plants.
Adi Millman @AdiMillman
1K Followers 700 Following Postdoctoral Fellow at the Laub Lab @MITBiology | PhD @SorekLab @WeizmannScience
Laina @LainaHall
136 Followers 443 Following Lover of science & being outside! 🧬🏔 @UCB_biophysics graduate student she/her
Andrew Santiago-Frang.. @SantiagoFrangos
2K Followers 1K Following Asst Prof @Penn. CRISPR Biology & Applications | Biochemist & CryoEM | #NIHMOSAIC K99/R00 + @BWFUND PDEP Fellow. View Mine.
Adam Ligeralde @AKTAguy
465 Followers 911 Following Your continued technical resource for #proteinpurification using ÄKTA™ #chromatography systems, columns & resins. Follow me now @InsightSherpa
alex meeske @alexjmeeske
1K Followers 753 Following Assistant Professor in @UW Dept. of Microbiology studying CRISPR-Cas functions in bacteria
Shady El-Husseiny @Husseinyyy
1K Followers 2K Following Postdoc @BuchholzLab_TUD with strong interest in #KRAS, #CRISPR Base Editing and #Organoids | He/him 🇪🇬🇩🇪
Jennifer R Hamilton @JRo_Hamilton
2K Followers 1K Following CRISPR + gene therapy delivery 👩🔬 NIGMS K99 @doudna_lab & women in enterprising science fellow @igisci
@[email protected].. @PubPeer
33K Followers 265 Following https://t.co/BfbqrNmwTZ for open evaluation of science. https://t.co/lziglOmh4S to select the best science.
Fatwa Adikusuma PhD @Fatwa_Adikusuma
3K Followers 1K Following Research Scientist, Medical School Adelaide University & SAHMRI, Genome editing lab. Molecular Biologist. CRISPR therapy. ARC DECRA fellow 2023-2025.
Rio Hermantara @riohermantara
205 Followers 570 Following Dad, husband, son, brother; PhD in Cancer Sciences/CRISPR-gene editing @UofGlasgow HoD of Biomedicine study program, i3L, Jakarta
Kevin Zhao @kevintzhao93
828 Followers 736 Following @ForbesAsia 30 under 30 | MIT TR35 Asia | @SchmidtFellows CRISPR genome editing | Directed Evolution | Protein Engineering | Plants Harvard Chemistry PhD '21
Tom Ellis @ProfTomEllis
23K Followers 600 Following Synthetic Biology & Synthetic Genomics @ Imperial College London and the Sanger Institute. Bilingual in English and DNA. Also at https://t.co/f2Na2PES8R
TJ Cradick @NucleaseLab
1K Followers 797 Following CRISPR CSO, consulting and advising new gene editing companies. Alum: @ExcisionBio @CRISPRTx @GeorgiaTech @SangamoTx @UIowa @UCSF @MIT Tweets = own.„Once again, we find ourselves in the position of wondering how people in fashion are the only ones yet to see Zoolander.“ If you want to laugh at the absurdity of it all, you can’t do better than to read @MarinaHyde theguardian.com/commentisfree/…
Science educators searching for a compelling way to teach the importance of understanding how small molecules, macromolecules, and macromolecular assemblies differ: your quest is at an end.
Very happy to present our work on a CRISPR-associated transposon complex, previously shown at CRISPR2022 earlier this year. Immensely grateful to the wonderful team @Michael__Sch @irma_querques @OberliSeraina @ChrisChanez89. Congratulations! cell.com/cell/fulltext/…
Happy to share a new paper from my PhD!😊 Another work on ColE1 #plasmids, this time focused on their adaptation to the host (or is it the other way around?🤔). Huge thanks to @_bgzorn_'s guidance, and all the co-authors from @AruUcm and @metabolomicaceu! journals.asm.org/doi/10.1128/ms…
Among the many astounding capabilities of AI that I look forward to seeing in the future, ‘strategic lying’ is not one of them. “Cicero…infer[s] players' beliefs and intentions from its conversations and generat[es] dialogue in pursuit of its plans.” The future of marketing? 😱
AI has been destroying humans at adversarial games, like Chess or Go, for a bit. But now it is successfully outperforming humans at Diplomacy, the classic multiplayer game that requires natural language negotiations over chat, as well as strategic lying. science.org/doi/10.1126/sc…
As presented at CSHL CRISPR Frontiers, I'm excited to share our new manuscript on the discovery, biochemistry, & structural insights of novel phage-derived CRISPR-Cas systems and their development into gene-editing tools! Now published @CellCellPress sciencedirect.com/science/articl…
Sometimes the joke writes itself.
Me trying to come up with nonsense to posts for you to experience with thy eyeballs:
been in science for a long time now and i’ve given up on learning how to spell “fluorescence” as a form of self care
“A public accustomed to learning about science as a final product was perhaps perplexed to see science in the making.” This article by @CT_Bergstrom in @nytopinion is well worth a read! Would love to debate the questions he raises here! nytimes.com/2022/11/19/opi…
Always grateful to do science in the most beautiful of places! At RML, I've been using electron microscopy to look at viruses and bacteria. It's a very special feeling to peer into a world that few people see!
A variety of thought-provoking findings and hypotheses, but a bottom line well-known to most PIs: the productivity of our labs is primarily dependent on our trainees. Cherish and support them. science.org/doi/10.1126/sc…
Another big shoutout (before Twitter inevitably blows up 💥) to #Dav604's phenomenal paper on #CRISPR, jumbo phages and abortive infection. ☠️ Final version now online @MolecularCell: doi.org/10.1016/j.molc…
should i also make tutorial videos on how to use imagej, or do y’all think youtube’s already saturated with those videos? 🤔
@lab_shenanigans ImageJ how to: “… alright and now we close and reopen ImageJ because this function decided not to work again”
David Mayo-Muñoz et al. from the @PeterFineran Lab reveal how NucC activated by Type III CRISPR protects bacteria against jumbo phages. Fascinating! 🔥👇 cell.com/molecular-cell…
The final version of our #CRISPR - NucC - jumbo #phage paper is out! Access it here: authors.elsevier.com/c/1g5cX3vVUPK9… @MolecularCell Awesome work led by the fantastic PhD candidate David Mayo Muñoz 🎉 #Dav604 Summary below 👇
Some jumbo phages shield🛡their DNA 🧬within a nucleus structure…so what’s a CRISPR-Cas ✂️ to do? See🧵 summarizing our recent findings on how type III-A CRISPR-Cas RNA-recognition triggers abortive infection via the DNase NucC & so much more! 👇 biorxiv.org/content/10.110…
The S. solfataricus Csm (III-D) CRISPR effector, with 8 unique subunits - great collaboration with @Laura_Spagnolo_ and heroic protein production by @shrlgrl
And here's our latest preprint, on work done as a wonderful collaboration with @mfwhite2: biorxiv.org/cgi/content/sh… #CRISPR @biorxivpreprint
We now put a new #CDlab paper on @biorxivpreprint where we use our recently introduced nanopore single-protein scanning method (see here x.com/cees_dekker/st… ) to detect single PTMs within single molecules: biorxiv.org/content/10.110… 4/
Today we publish a paper in @ScienceMagazine that expands nanopore readings to the proteome: a nanopore-based scanner to read off PROTEINS at the single-molecule level! 🤩 Awesome experiments by postdoc Henry Brinkerhoff of our #CDlab, with MD simulations of @aksimentievLab 1/x
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