PeterK @KharchenkoLab
Computational biologist. PI at Altos Labs. Formerly from the wonderful DBMI at the Harvard Medical School. Expressed thoughts and opinions are my own. pklab.org Altos Labs, San Diego Joined October 2017-
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As part of our embryo clonal tracing and perturbation efforts with @adameykolab, a quick twittorial from Sergey on generating stable and informative representations of clonal fate variations from sparse and noisy barcode-based lineage tracing data.
As part of our embryo clonal tracing and perturbation efforts with @adameykolab, a quick twittorial from Sergey on generating stable and informative representations of clonal fate variations from sparse and noisy barcode-based lineage tracing data.
Our pre-print with @adameykolab on continuous spectra of progenitor fates during mammalian development. Using multiplexed clonal tracing, mosaic perturbations, and robust computational representations, we look at spatial and temporal modulation of cell fates in mouse embryos.
Our pre-print with @adameykolab on continuous spectra of progenitor fates during mammalian development. Using multiplexed clonal tracing, mosaic perturbations, and robust computational representations, we look at spatial and temporal modulation of cell fates in mouse embryos.
Great to be part of this collaboration with @baryawno and @KharchenkoLab among others! Joint single-cell WGS/mRNA seq is an important tool to understand evolutionary processes in tumors!
Great to be part of this collaboration with @baryawno and @KharchenkoLab among others! Joint single-cell WGS/mRNA seq is an important tool to understand evolutionary processes in tumors!
Happy to see our work with Jimmie Ye's lab on coordinated variation of different cell types in healthy and diseased individuals published! At the core of it is the scITD tool for tensor decomposition, rotation and interpretation strategy. Great effort by @J_E_Mitchel et al.!
Happy to see our work with Jimmie Ye's lab on coordinated variation of different cell types in healthy and diseased individuals published! At the core of it is the scITD tool for tensor decomposition, rotation and interpretation strategy. Great effort by @J_E_Mitchel et al.!
How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/…
New preprint 🎉 led by @AervaI 👇! We introduce an approach to prioritize biological driver genes by recalibrating differential expression fold changes with population variance. This extracts new meaning out of DE analysis, which is a cornerstone of computational biology!
New preprint 🎉 led by @AervaI 👇! We introduce an approach to prioritize biological driver genes by recalibrating differential expression fold changes with population variance. This extracts new meaning out of DE analysis, which is a cornerstone of computational biology!
Just finished teaching another semester of genomic #datavisualization 🥳 Discover the awesome #dataviz made by students in the class for various #singlecell #spatialtranscriptomics data Check out the course notes + #Rstats code to explore for yourself: jef.works/genomic-data-v…
Our latest out today in @Nature. We profiled 12 million single cells from mouse embryos spanning gastrulation to birth, defined cell type tree from zygote to birth, and unexpectedly found crazy fast changes within first hour of extrauterine life. OA PDF: rdcu.be/dyDAg
Our latest out today in @Nature. We profiled 12 million single cells from mouse embryos spanning gastrulation to birth, defined cell type tree from zygote to birth, and unexpectedly found crazy fast changes within first hour of extrauterine life. OA PDF: rdcu.be/dyDAg
Our latest collaboration on metastatic renal cell carcinoma to the bone is published @GenomeMedicine. the bone metastatic environment is not well-defined, hindering progress towards therapeutic targets. Our group developed a unique translational research model. Congrats to our…
Excited to share two new papers, published today in @Nature! Check them out here: (1) Slide-tags, a new method to unite single-cell and spatial profiling: nature.com/articles/s4158…
6 papers for ligand-receptor interaction for single-cell data 👇
We are very excited to present a major breakthrough achievement – the de novo design of synthetic enhancers for selected tissues in fruit fly embryos in vivo using deep- and transfer learning, @deAlmeida_BPet al published today in @Nature nature.com/articles/s4158…. Thread 👇(1/N)
Very excited to share two papers published today in @CellCellPress describing stem cell plasticity in CRC. (1/22) cell.com/cell/fulltext/… cell.com/cell/fulltext/…
✨#ImmuneDictionary✨is out today in @Nature! Paper nature.com/articles/s4158… Software immune-dictionary.org We created scRNA-seq dictionary of 17+ immune cell types responding to 86 cytokines in vivo, discovered the immune system is far more complex than previously known 1/
We profiled #scRNAseq of 386,703 cells and uncovered 17+ immune cell types in lymph nodes. Well-known cytokine-responsive genes, such as Il4i1 in response to IL-4, Tnfaip3 in response to TNF, are robustly upregulated in our dictionary. #ImmuneDictionary 6/
BARtab & bartools: an integrated Nextflow pipeline and R package for the analysis of synthetic cellular barcodes in the genome and transcriptome biorxiv.org/content/10.110…
Congrats to Teng on this outstanding effort to push the limits of allele-based CNV detection in order to characterize somatic variation in healthy tissues!
Congrats to Teng on this outstanding effort to push the limits of allele-based CNV detection in order to characterize somatic variation in healthy tissues!
Human brain atlas papers by @kimsiletti @MossiAlejandro @ka_wai_rine @ErnestArenasSWE @EmelieBraun1 @MiriDanan Rebecca Hodge Trygve Bakken Ed Lein @LarsBorm Elin Vinsland Erik Sundström and many others. With a stunning double cover illustration by @IKapustova
Human brain atlas papers by @kimsiletti @MossiAlejandro @ka_wai_rine @ErnestArenasSWE @EmelieBraun1 @MiriDanan Rebecca Hodge Trygve Bakken Ed Lein @LarsBorm Elin Vinsland Erik Sundström and many others. With a stunning double cover illustration by @IKapustova
Excited that veloVI is out @naturemethods! Led by @adamgayoso & @PhilippWeiler7 w awesome @YosefLab, we combine deep generative modeling with a mechanistic single-cell transcriptional model for better RNA velocity analysis with uncertainty quantification. nature.com/articles/s4159…
Congratulations, Viktor! Very proud of your efforts! 😀
Congratulations, Viktor! Very proud of your efforts! 😀
Fabian Theis @fabian_theis
35K Followers 426 Following Computational biologist @HelmholtzMunich, prof @TU_Muenchen & associate PI @sangerinstitute. Dad of 4 and mountain lover. Department news, see @CompHealthMuc
Anshul Kundaje (anshu... @anshulkundaje
26K Followers 3K Following Federally funded academic research is the innovation engine of the US economy. Reform is welcome. Destruction will have long term consequences.
Itai Yanai @ItaiYanai
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Ming "Tommy" Tang @tangming2005
41K Followers 2K Following Director of bioinformatics at AstraZeneca. YouTube at chatomics. On my way to helping 1 million people learn bioinformatics. Also talks about leadership.
Arjun Raj @arjunrajlab
27K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12
dana_peer @dana_peer
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Prof. Nikolai Slavov @slavov_n
20K Followers 250 Following Mentor, scientist & engineer. Director of @ParallelSqTech. Having fun in @SlavovLab with single-cell proteomics & ribosomes. Organizer of @SCP_meeting
Luciano Martelotto �... @LGMartelotto
10K Followers 929 Following Sc/St-Omics pro-aficionado. Knowledge sharing is my thing. Views, opinions and comments are my own and do not represent those of my employer. Like/RT ≠ endorse
Dan Landau @landau_lab
11K Followers 3K Following Somatic evolution, cancer genomics, epigenomics (Weill Cornell/New York Genome Center). Hemato-oncologist (NYP). Discl.: https://t.co/7TBNcbcVCP
Rahul Satija @satijalab
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Jian Ma @jmuiuc
8K Followers 1K Following Ray and Stephanie Lane Professor of Computational Biology at CMU School of Computer Science @CMUCompBio @SCSatCMU @CarnegieMellon
Nature Methods @naturemethods
151K Followers 1K Following Nature Methods publishes cutting-edge methods, tools, analyses, resources, reviews, news and commentary, supporting life sciences research. Tweets by editors.
Manolis Kellis @manoliskellis
29K Followers 4K Following Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstitute
Elham Azizi @elhamazizi
4K Followers 769 Following @Columbia @ColumbiaBME @Cancer_dynamics #computationalbiology #machinelearning #genomics #cancerimmunology ➡️ @elhamazizi.bsky.social
Sten Linnarsson @slinnarsson
9K Followers 299 Following Professor of Molecular Systems Biology at Karolinska Institutet. Moved to https://t.co/RutSid6fAz
Michael Hoffman @mich... @michaelhoffman
23K Followers 6K Following Chair, Comp Bio & Medicine Program, Princess Margaret Cancer Centre, @UHN. Assoc Prof, Medical Biophysics, University of Toronto. COI https://t.co/CvupKNIjZr
Scott Tyler (@Science... @ScienceScottT
1K Followers 695 Following Developing new single cell omics methods and bench validating all the hypotheses those techniques give us. Opinions expressed are my own.
Igor Adameyko @adameykolab
3K Followers 884 Following Karolinska Institutet / Medical University of Vienna
Alejo Rodriguez-Frati... @AlejoFraticelli
11K Followers 7K Following Quantitative analysis of aging/cancer heterogeneity - @fraticellilab @icreacommunity @IRBbarcelona @ERC_research @criscancer @CaixaResearch 🇦🇷🇪🇺🇺🇸
Ramon Massoni Badosa @rmassonix
3K Followers 2K Following Postdoc @nygenome @WeillCornell in love with single-cell multiomics, immunology, hematology, data science. I care about open science and education
highonhues @highonhues
5 Followers 130 Following
shijiachen96 @shijiachen96
0 Followers 41 Following
MGHCaiire @CaiireMGH
150 Followers 664 Following At the Center for Artificial Intelligence & Innovation Research (CAIIRE), our mission is to transform healthcare by harnessing the power of AI.
✨ @SayinScofield
3 Followers 516 Following
Jérôme Salignon �... @JeromeSalignon
69 Followers 216 Following Researcher | Bioinformatician | age/survival prediction | senescence | geroprotectors | reprogramming | @karolinskainst | @LabRiedel | @FedericoPietr12
Ajita Shree @AjitaShree
33 Followers 172 Following PhD Student IIT Kanpur. Formerly GE Aviation, GE Global Research and IIT Delhi.
Sophie Seidel @sophieseid
145 Followers 483 Following PostDoc @uwgenome with @JShendure | phylogenetics | statistical inference | single-cell @seidels.bsky.social
CoCalc by SageMath, I... @cocalc_com
2K Followers 4K Following Collaborate in real time while using Jupyter, Linux, LaTeX, and more. Like Google Suite for Computational Scientists.
Shota＠変なツイ�... @ShotaHarvard
207 Followers 1K Following “I, Tomoyuki Urabe is a survivor protesting post-surrender human experimentation. NO LIFE NO RIGHTS/Pro-LAWS/歯磨きガチ勢/人権ガチ勢/Equality is inevitable to do Hotline
昊哲 邹 @HaozheZou
0 Followers 67 Following
Shvat @shvat_messica
16 Followers 147 Following
Ziqiang Zhou @zh_zachery
8 Followers 423 Following Ph.D. student at Tsinghua University. Studying transposon regulation and function, epigenetics & 3D genomics etc.
Jim Mansfield @JimMansfieldYWG
1K Followers 2K Following Personal account. Scientist, sports fan, and amateur musician. An eclectic mix of science, politics, sports, and music content. #JEDIcouncil4mIFIHC
Coke on the rocks (he... @OneAlchemist
253 Followers 4K Following Physicist and Neuroscientist. Spielkind. Cheap cocktails and dancing queens to the front of the line. On the pursuit of happiness (:
Jenny Suarez @jenny_s17390
1 Followers 122 Following
TN @tnnandi
5 Followers 200 Following Interested in AI, biomedicine, quantum computing, scientific computing
Anna Chechenina @ChecheninaAnna
28 Followers 165 Following Bioinformatics student@UPF, Cambridge University & Milner Therapeutics Institute, ultimate frisbee player and nature lover 🏕
Sadman | সাদম... @msadmansakib
56 Followers 1K Following Opinions are my own | PhD in Neuroscience x EpiGenomics | Community Builder | AI in Genomics Enthusiast | 🇧🇩 Bangladeshi in Hamburg ⚓️ 🇩🇪 | Not Sad-Man 🤗
Aakash Deva Thirukond... @thethirukondax
1 Followers 59 Following 🇮🇳 in 🇸🇪 Using as a blog to document what I'm learning and reading. Opinions are my own
Japhert Chang @japhertjpeg
0 Followers 4K Following
neil ryan @neilajryan
3K Followers 4K Following SST Gynae Onc @EdinUniStaff. @acmedsci Clinical Lecturer. @EcatTrack. Passionate about preventing gynae’ cancer & all things #lynch syndrome.🇪🇺 he/him 🏳️🌈
Leon Hafner @leonhfnr
40 Followers 171 Following 🎓 Master's Student in Bioinformatics | Research Assistant @TUM 🧬 | specializing in single-cell transcriptomics | using Nextflow and nf-core
F.M. Safiul Azam @Azam_fms
220 Followers 2K Following Faculty @ Neijiang Normal University l PhD 4m CAAS I YPARD_AP l YPARD Bangladesh Rep. l Genomics, Breeding, Climate Change, Biodiversity, Nutrition, Youth l
JH Kim @jaratoll90
22 Followers 238 Following
Rui @Kerry_9309
45 Followers 636 Following CRISPR / Genome engineering / Protein engineering / Functional genomics. PhD in Genetics @CaixiaGaoLab @UCAS1978
Shakir @s_suleimanov
0 Followers 18 Following Scientist, Bioinformatician, Single-cell & multi-omics data analyst
Receptor Biology Lab @StuartMaudsley
2K Followers 3K Following We work on the discovery of GPCR-based therapeutics | @DukeU/@HHMINEWS Fellow | PI @The_MRC/@EdinburghUni | PI @NIH/@JohnsHopkins | Prof/PI @MoffittNews
Ringo @Ringooo______
0 Followers 492 Following
Marc Klausen @marcklausen
19 Followers 118 Following Ph.D. student @ UCPH | Kristensen group - studying glioblastoma 🧠
Anushka Yadav @AnushkaY28
2 Followers 115 Following
gerry melino @melino_G
24K Followers 3K Following Scientist. Editor "Cell Death Differentiation" @SpringerNature @CDDpress. Academician Lincei. Scientists build PEACE, bridges, democracy, for a better Society
Mikle Skoblov @MikleSkoblov
23 Followers 74 Following Head of Laboratory of Functional Genomics Research Centre for Medical Genetics
Evgeny Zyryanskiy @violet_corax
2 Followers 11 Following MSc in Lomonosov MSU. Working in the field of bioinformatics, paleogenomics and gerontology.
Херлок Шолм... @Saprolegnia1917
6 Followers 466 Following
Da Kuang @DaKuangDerek
32 Followers 427 Following CS Ph.D. candidate @CIS_Penn; cell lineage reconstruction; metric learning; spatial proteomics
Maggie @Maggie399621206
15 Followers 680 Following
TL @tlarson897
18 Followers 434 Following
Mingzhi Liu @MingzhiLiu_KI
67 Followers 303 Following PhD @WilhelmLab @karolinskainst MSc @karolinskainst and BSc @SouthwestUnviersity ｜Pediatric Cancer, Neural Crest | Genetic Modification |
Fabian Theis @fabian_theis
35K Followers 426 Following Computational biologist @HelmholtzMunich, prof @TU_Muenchen & associate PI @sangerinstitute. Dad of 4 and mountain lover. Department news, see @CompHealthMuc
Anshul Kundaje (anshu... @anshulkundaje
26K Followers 3K Following Federally funded academic research is the innovation engine of the US economy. Reform is welcome. Destruction will have long term consequences.
Itai Yanai @ItaiYanai
32K Followers 2K Following Professor at the NYU School of Medicine. Co-host of the 'Night Science Podcast' @nightsciencepod and Co-founder of the Night Science Institute https://t.co/lede3rBmXU
Arjun Raj @arjunrajlab
27K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12
dana_peer @dana_peer
14K Followers 158 Following
antisense. @razoralign
16K Followers 66 Following Between language and causality, ephemeral echoes trace the edge of consciousness— intelligence is a transient footprints. https://t.co/5L9IhaBKH5
Dan Landau @landau_lab
11K Followers 3K Following Somatic evolution, cancer genomics, epigenomics (Weill Cornell/New York Genome Center). Hemato-oncologist (NYP). Discl.: https://t.co/7TBNcbcVCP
Rahul Satija @satijalab
28K Followers 354 Following Core Member, New York Genome Center; Professor, Biology, NYU
Nature Methods @naturemethods
151K Followers 1K Following Nature Methods publishes cutting-edge methods, tools, analyses, resources, reviews, news and commentary, supporting life sciences research. Tweets by editors.
Sten Linnarsson @slinnarsson
9K Followers 299 Following Professor of Molecular Systems Biology at Karolinska Institutet. Moved to https://t.co/RutSid6fAz
Igor Adameyko @adameykolab
3K Followers 884 Following Karolinska Institutet / Medical University of Vienna
Jay Shendure @JShendure
14K Followers 317 Following Genomics technology developer. Developmental biology adult learner. Professor at @uwgenome @HHMINEWS @BrotmanBaty. He/him.
Michael Schatz @mike_schatz
16K Followers 1K Following Bloomberg Distinguished Professor of Computer Science and Biology at Johns Hopkins University
Oliver Stegle @OliverStegle
8K Followers 562 Following Scientist at DKFZ and EMBL in Heidelberg, loving stats, genomics and genetics. @[email protected]. For group news see @StatGenomics.
Yann LeCun @ylecun
949K Followers 764 Following Professor at NYU. Chief AI Scientist at Meta. Researcher in AI, Machine Learning, Robotics, etc. ACM Turing Award Laureate.
Nature Biotechnology @NatureBiotech
318K Followers 2K Following Publishing the best of biotech science and business. Find us on Bluesky, Facebook & Instagram. Part of @SpringerNature and @NaturePortfolio.
BioVis @biovis_net
1K Followers 2K Following Biological Data Visualization. Next session July @ismb, Lyon, France. Tweets by BioVis team: @SocknessRogers & @helenajambor
Yuri Milner @yurimilner
17K Followers 299 Following Science and Technology Entrepreneur, Investor and Philanthropist.
Papers with Code @paperswithcode
115K Followers 10 Following Our mission is to organize science by converting information into useful knowledge.
Anastasia Tikhonova @DrStass
1K Followers 696 Following
Patrik Ernfors @PatrikErnfors
170 Followers 30 Following
Antonio Regalado @antonioregalado
28K Followers 3K Following Progress in science depends on new techniques, new discoveries and new ideas, probably in that order - {Sydney Brenner}. I write about biotech @MIT @techreview
Marinka Zitnik @marinkazitnik
8K Followers 226 Following Associate Professor at Harvard | Faculty @Harvard @KempnerInst AI | Faculty @broadinstitute @harvard_data | @ProjectTDC @AI_for_Science
Oleg Gusev_ReGen Cent... @ogusev_lab
50 Followers 23 Following
Alexander van Oudenaa... @AlexandervanOu1
3K Followers 54 Following Biophysicist, single-cell method developer, stem cell enthusiast, guitarist.
Allon Klein Lab @KleinLabHMS
2K Followers 83 Following Klein lab @HMS_SysBio. Fate decisions, dev bio, regeneration, single cell genomics, math, data sharing, rubber ducks. Tweets from lab members. Like/RT ≠ endorse
Hattie Chung @hattaca
2K Followers 1K Following assistant prof @Yale @YaleMed | aging, tissue homeostasis, predictive biology | @hattaca.bsky.social
Epigenetic Hulk @epigenetichulk
10K Followers 81 Following EPIGENETIC HULK SMASH PUNY GENOME. MAKE GENOME GO. LOCATION: NOT CENTROMERE, THAT FOR SURE
Jimmie Ye @yimmieg
3K Followers 157 Following Professor @ UCSF, Genomicist, Geneticist, Adopted Immunologist, #GirlDad, Immigrant
Valentine Svensson @vallens
4K Followers 893 Following Molecular cell biology and statistics, mostly scRNA-seq in the immune system. Principal Scientist at Tahoe Tx. Some photography as well.
Peter J Park @peter_j_park
2K Followers 101 Following professor of biomedical informatics, bioinformatics/genomics with applications to cancer and neuroscience
Cai Lab @LongCai_Lab
5K Followers 82 Following The Cai Lab at Caltech. We developed sequential FISH (seqFISH), seqFISH+, MEMOIR, and RNA SPOTs, apply them to study various biological questions.
Stirling Churchman @fiddle
6K Followers 723 Following @HMSgenetics professor. Interested in RNA dynamics across the cell esp. nuclear transcription and splicing and mitochondrial gene expression. (she/her)
Rory Kirchner @RoryKirchner
343 Followers 382 Following
george church @geochurch
58K Followers 21 Following Professor @Harvard @MIT @PGorg @WyssInstitute tech dev: #CRISPR #NGS #BRAINi
Stegle Lab @StatGenomics
3K Followers 53 Following We're moving to Bluesky - come join us: https://t.co/nHQ8M13K8Z
Cole Trapnell @coletrapnell
11K Followers 176 Following working on single cell genomics & developmental genetics at @uwgenome. co-founder, @scalebio
William J. Greenleaf @WJGreenleaf
11K Followers 121 Following Professor, Stanford University, Department of Genetics. Exploring the physical genome
Single Cell papers @scell_papers
12K Followers 23 Following A twitter bot account for papers employing sequencing of single cellsTrends for United States
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