Kerstin Lindblad-Toh Lab @KltLab
Comparative genomics and genetics at Uppsala University @UU_University and Broad Institute @broadinstitute lindbladtohlab.org Joined February 2020-
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Vårt projekt om hur vi med nya metoder letar cancergener och där förståelsen kan leda till en mer skräddarsydd behandling var ett av de 224 som fick anslag från @Cancerfonden! Tack alla som skänker gåvor till forskningen och gör detta möjligt! #tillsammansmotcancer #cancerfonden
🐕Let the new analyses begin! 🐩 Proud to be a driver of the #dog10K analysis of 2000 genomes, and to see the release of 48M variants, an #imputation panel, data harmonisation pipelines & more #dog #genomics @uppsalauni @scilifelab @KltLab genomebiology.biomedcentral.com/articles/10.11…
#Dog10K consortium with @DrJenMeadows & @KltLab publishes the analysis of 2000 genomes, releasing >48M variants, an imputation panel & data harmonisation pipelines for genomics community. Let the new analyses begin! @GenomeBiology @scilifelab @uppsalauni doi.org/10.1186/s13059…
In our new study, we identify novel candidate cancer driver genes in medulloblastoma by using evolutionary constraint. The results imply different molecular pathways in different patient groups opening for specified diagnostics and personalized treatment. www-pnas-org.ezproxy.its.uu.se/doi/10.1073/pn…
Special issue of Science science.org/doi/10.1126/sc… - 11 papers from the @ZoonomiaProject comparing the genomes of 240 mammals. A fantastic effort for understanding mammals, mammalian evolution and ourselves. @eenork @ScienceMagazine @UMassChan @UU_University @broadinstitute
"In humans worldwide, the Zoonomia studies [genomes from 240 placental mammals] demonstrate how explicitly thinking about humans as a mammal among mammals can substantially enrich our understanding of the emergence of evolutionary novelty and human uniqueness."
From the @ZoonomiaProject — the largest comparative genomics resource in the world — comes a package of papers that compare the genomes of 240 mammals. Learn more: broad.io/Zoonomia @eenork @KltLab @ScienceMagazine @sandiegozoo @UMassChan @UU_University
A team co-led by Elinor Karlsson, PhD, is showing how much we can learn from studying the genomes of mammals. Read about the 13 studies published in @ScienceMagazine that help scientists better understand health and disease: direc.to/jmQ6 @eenork @KltLab @broadinstitute
För en populärvetenskaplig sammanfattning om vår nya publikation kring atopiskt eksem hos hund, se pressmeddelandet på Uppsala universitets hemsida: uu.se/press/pressmed…
For a short popular scientific summary about our new canine atopic dermatitis paper, check the press release from Uppsala University: uu.se/en/press/press…
nature.com/articles/s4200… New! We use Bayesian and selection methods to find genetic risk factors for canine atopic dermatitis in 4 breeds. 15 associated loci, 8 selection regions, many indicating interesting similarities between canine and human AD. #caninehealth #atopicdermatitis
An interesting new study from our colleagues at Broad Institute investigating behavioral and other traits in more than 2000 purebred and mixed-breed dogs. science.org/doi/10.1126/sc…
Earth BioGenome Project #EarthBioGenome @EBPgenome moving from pilot projects to full-scale sequencing of all plants, animals, fungi and other microbial life on Earth. 3 great papers out in PNAS this week with contribution from @scilifelab pnas.org/content/119/4/…
Eric Axelsson and colleagues present WGS data from 8 dog breeds, showing that cavalier King Charles spaniels carry more harmful genetic variants than other breeds in the study and identify candidate risk alleles for the heart disease MMVD. journals.plos.org/plosgenetics/a…
Kerstin Lindblad-Toh research dog disease genetics to find out how it can be applied to humans. Her goal is for the new findings to translate into personalized diagnostics and health care #KAW100 #genetics #immunology @UU_University @broadinstitute bit.ly/3cQeaA9
Kerstin Lindblad-Toh forskar på sjukdomsgenetik i hundar för att ta reda på hur kunskapen kan överföras till människor och i skräddarsydd diagnostik och vård i framtiden #KAW100 #genetik #immunologi @uppsalauni #sle #cancer bit.ly/3xq4tjG
Interview and discussion in Swedish at UppTalk Weekly: Hur kan folksjukdomar som cancer och tvångssyndrom förklaras med DNA från hundar? youtu.be/QjN4lMVdrsU
Our research is getting noticed! This paper comparing the genomics of canine hemangiosarcoma and human angiosarcoma is one of Molecular Cancer Research's most cited of 2019. Another success to put on the "post-pandemic celebrate list"! mcr.aacrjournals.org/content/17/12/…
Delighted to be a part of this new study presenting findings about the genetic basis of dog freckles, the "ticked" phenotype, from @prof_claire and collaborators onlinelibrary.wiley.com/doi/full/10.11…
SciLifeLab @scilifelab
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