Costanzo’s Lab @LabVincenzo
We study basic mechanisms of genome stability maintenance altered in cancer Joined June 2024-
Tweets65
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Followers229
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Following679
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Costanzo’s Lab retweeted
Excited to share our latest research “DNA2 enables growth by restricting recombination-restarted replication” in @Nature defining DNA2’s essential function and elucidating links to primordial dwarfism and cancer. Thanks to the team and all collaborators! nature.com/articles/s4158…
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Costanzo’s Lab retweeted
📢 For all HaloTag lovers💙💚💛❤️💜🩶 we are excited to share that our work, in which we developed a new biotin-HaloTag ligand, is now published in @JCellBiol! Full link here: rupress.org/jcb/article-ab…
Costanzo’s Lab retweeted
The application deadline has been extended for a postdoc position in our lab until August 22. Please enquire/apply if you are interested in ADP-ribosylation, ubiquitination, genome stability or immunity. my.corehr.com/pls/uoxrecruit…
Costanzo’s Lab retweeted
🚨 Hot off the press!!! Wanted to share this to celebrate the momentous achievement from the @GiuntaLab and for the human centromere / genomics communities as a whole... more posts to come next week but for now, happy Fourth & happy reading ❤️🧬💻 science.org/doi/10.1126/sc…
Costanzo’s Lab retweeted
Online Now: The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells dlvr.it/TLZtS1
Costanzo’s Lab retweeted
Online Now: The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks dlvr.it/TLZkmH
Costanzo’s Lab retweeted
Uracil-induced replication stress drives mutations, genome instability, anti-cancer treatment efficacy, and resistance dlvr.it/TKqSww
Three days, fresh data, & sparkly debates on how replication gaps drive cancer & disease. Grateful for every talk & discussion. Thank you for pushing science forward—next stop: great papers. Science moves fast when we move together!
Costanzo’s Lab retweeted
Truly honored that my career path and laboratory have been featured in the 'Cell Scientist to Watch' interview series. A huge thank you Sara Morais da Silva and @J_Cell_Sci for this wonderful opportunity 🙏
Truly honored that my career path and laboratory have been featured in the 'Cell Scientist to Watch' interview series. A huge thank you Sara Morais da Silva and @J_Cell_Sci for this wonderful opportunity 🙏
Costanzo’s Lab retweeted
It's out! nature.com/articles/s4158… Structure of the two RAD52 rings forming a spool-like structure at replication fork, rearranging and protecting the fork. Tour-de-force work by Masa Honda and Ali Razzaghi and wonderful (as usual) collaboration with @PietroPichierri 's lab.
Costanzo’s Lab retweeted
🙏 Thank you, @3reak, @LabVincenzo, and Evident, for fantastic collaboration! Special thanks go to the exceptionally talented postdoc Paolo Fagherazzi and the brilliant image analysis specialist Timo Diekmann for their extraordinary efforts! 🙏
Costanzo’s Lab retweeted
Thrilled to share our latest work at @ScienceAdvances. Great collab with Costanzo, Masson, Freire and Reyes labs. HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells | Science Advances science.org/doi/10.1126/sc…
Costanzo’s Lab retweeted
Gaps may be small but meeting will be big! come join us!youtube.com/watch?v=KgBUEc…
Costanzo’s Lab retweeted
Sign up now to enjoy a $200 discount on your registration for the DNA Replication Gaps, Cancer, and Disease event this April in Daejeon, South Korea. Don't wait, as this special offer expires on March 11 at 11:59pm MST. keysym.us/KSDNARep25 #KSNDNARep25 youtu.be/qvZBNKck0z0
Costanzo’s Lab retweeted
We are delighted to share our latest work, characterising the role of BRCA2 and its binding partner PALB2 at centromeres, just out in the latest issue of Cell Reports. cell.com/cell-reports/f…
Costanzo’s Lab retweeted
Congratulations Jenna Whalen on her Nature Cancer pub out today- nick toxicity linked to resection! rdcu.be/d60Td
Join the first Keystone conference dedicated to DNA Replication Gaps, Cancer and Disease! Send an abstract to be selected for a talk. keystonesymposia.org/conferences/co…
Costanzo’s Lab retweeted
Deadlines are approaching for @KeystoneSymp #DNAReplication Gaps, Cancer and Disease, this April in Daejeon! See scholarship, abstract and discount reg dates: keysym.us/KSDNARep25 #KSDNARep25
Costanzo’s Lab retweeted
Check out and join us for an interesting interdisciplinary PhD project! Deadline on 10th of Jan. DNA replication and cancer research 🥹. Please RT
Check out and join us for an interesting interdisciplinary PhD project! Deadline on 10th of Jan. DNA replication and cancer research 🥹. Please RT
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