Wyllie lab @dundee @LabWyllie
We determine the mode of action of compounds with potential to treat neglected tropical diseases. Opinions are my own. University of Dundee Joined May 2019-
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Today's paper writing sound-track is Neil Diamond! What have I become??
New paper alert! Oldie but goodie from the Fairlamb lab. Thanks to @FairlambAlan for coordinating! @UoDLifeSciences @WCAIRDundee journals.plos.org/plosntds/artic…
Very interesting paper on the pterines in Tryps. In my TODO list for the weekend! Well done @LabWyllie and @FairlambAlan journals.plos.org/plosntds/artic…
You can find our work here:
A new series of #quinazoline compounds can neutralize #Tcruzi and related parasites by targeting the enzyme KRS1 and has partially efficacy in mice with acute #ChagasDisease, according to a new proteomic and structural analysis. @LabWyllie @WCAIRDundee scim.ag/4nJm6pF
A true testament to collaboration in science with @LabWyllie and many more wonderful colleagues - our work in drug development for #neglectedtropicaldiseases has been published in Science Translational Medicine! @dmuleicester science.org/doi/10.1126/sc…
Nice news story about our latest paper @UoDLifeSciences dundee.ac.uk/stories/resear…
Delighted our latest paper is now published in Science Translational Medicine. Fantastic collab with @DrBhambra and his team. Our studies reveal promising quinazolines selectively target KRS in T. cruzi. @DundeeLifeSci @WCAIRDundee science.org/doi/10.1126/sc…
Fantastic paper from MoA group alumni Richard Wall and colleagues. 🙌 nature.com/articles/s4158…
Well done to Papua New Guinea 🇵🇬 on eliminating trachoma as a public health problem. This success is a powerful example of what targeted investment in neglected tropical diseases (NTDs) can achieve. #BeatNTDs #UniteActEliminate
New paper alert! Our work to determine the molecular target of a thienopyrimidinone demonstrating anti-malarial activity. Congrats to Natalie Wiedemar who led this work. pubs.acs.org/doi/10.1021/ac…
A new study models the impact of the implosion of U.S.-funded disease treatment and prevention in the developing world — and suggests that Elon Musk and Marco Rubio will go down as among history’s greatest monsters if funding and effective administration are not restored. 🔗…
Fantastic evening listening to the inspiring @dmac68 in St Andrews last night. Amazing stories and science.
I'm excited to share that the lab has been awarded a Career Development Award from the @wellcometrust . £2.9 million for 8 years. We will soon be looking for postdocs. Read more here: pawlowiclab.org/2025/03/05/new…
Stephen Fry, "The bullies have risen to the top" "I call it fascism because that's what it is" "It's a cult of power, and a cult of warrior worship, and a total contempt for the old world order" "You have to remember the psychology of the bully at school" "Bullies feast on…

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