Lea Lab @LeaLabTweets

Structural biology lab at NCI-Frederick. Formerly University of Oxford. Studying protein structures at the host-pathogen interface. All views are our own. Frederick, MD Joined February 2013

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Lea Lab @LeaLabTweets

a year ago

Thank you to @robinson_julia of Chemistry World (Royal Society of Chemistry) for a lovely write up of our work. Read the article here: chemistryworld.com/news/ultracold…. And for the original paper: nature.com/articles/s4156…

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Chemistry World @ChemistryWorld

a year ago

Using cryo-electron microscopy two different groups have revealed new insights into how flagellum power bacteria to get where they're going. @robinson_julia reports: chemistryworld.com/news/ultracold…

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Lea Lab @LeaLabTweets

a year ago

Reducing the complexity of a fascinating molecular motor. Read our Behind the Paper blog, where we detail our journey to deciphering the structural basis for how bacterial flagella shift into reverse gear: communities.springernature.com/posts/let-slip…

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Dunn_School (now @DunnSchool.bsky.social) @Dunn_School

a year ago

New meningitis vaccine developed by the @TangLabOxford! The new chimeric protein-based #vaccine to tackle #MenB is the result of a strategic collaboration between @UniofOxford & @SerumInstIndia Find out more: path.ox.ac.uk/news-article/n…

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Nature Microbiology @NatureMicrobiol

a year ago

Also hot off the press! Our latest article on the structural analysis of protein transport by the T9SS is out now 👇nature.com/articles/s4156…

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Kylie Walters (she/her) @kyliejwalters

a year ago

Thrilled to share that we teamed up across @theNCI and @nih_nhlbi to discover #degraders against #hRpn13 that trigger #apoptosis in #cancer cells in a study led by @xiuxiu_lu with structural data from @Monikachandrav2. 🎉 link.springer.com/10.1038/s41467…

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Susan Lea @S_M_Lea

2 years ago

Published today @SJohnsonDPhil and @justindeme85 story finally revealing the molecular basis for transmission of uni-directional ion flow into bi-directional rotation of the bacterial flagellum doi.org/10.1038/s41564…

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Owain James Bryant @OJ_Bryant

2 years ago

Check out our latest paper where we identify a new C-terminal export signal in flagellar Type III secretion substrates which provides further evidence against a subunit capture/chain mechanism for flagellar assembly. doi.org/10.1128/mbio.0…

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Stephen Garrett @StephenRG97

2 years ago

Very happy to share some work from my PhD which is now published in Nature Communications! We have identified a new type of T7SS substrate which has a strange ‘reverse’ secretion signal. doi.org/10.1038/s41467…

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Owain James Bryant @OJ_Bryant

2 years ago

Check out our new paper @ nature.com/articles/s4146… from my time working in the fantastic Chung lab @TranslatingRNA. Also check out our "Behind the Paper" post go.nature.com/3GCnE09. @ Filip Lastovka, @TranslatingRNA, @CamPathology, @OJ_Bryant. More to come from us soon!