Leeds Integrative Membrane Biology @LeedsIMB
An interdisciplinary research theme in the School of Biomedical Sciences at the University of Leeds, focussing on membrane proteins in health and biotechnology. biologicalsciences.leeds.ac.uk/integrative-me… Leeds, U.K. Joined September 2019-
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In our latest article we found structural correlation between pocket modification and tension activation in the MscL channel using pulsed EPR, HDX and MD: cell.com/structure/full… @Bolin83814396 @95bjl @anton_calabrese @FrankSobott @KalliGroup @EPR_ESR @RSC_ESR @AstburyCentre
In our latest article we found structural correlation between pocket modification and tension activation in the MscL channel using pulsed EPR, HDX and MD: cell.com/structure/full… @Bolin83814396 @95bjl @anton_calabrese @FrankSobott @KalliGroup @EPR_ESR @RSC_ESR @AstburyCentre
Check out our new preprint: Mechanical and molecular activation lead to structurally analogous MscL states biorxiv.org/content/10.110… Great effort by @Bolin83814396 & @95bjl, @FrankSobott @anton_calabrese @KalliGroup at @AstburyCentre @ScienceLeeds @LeedsIMB @MassSpecLeeds
Took a while to get around the preferred orientation of HSPD1 but good to see the hard work of @DavidKlebl and the team @MatthewFeasey @HeskethEmma @RSBon_Lab @naranson @FrankSobott finally out. cell.com/iscience/fullt…
So excited to see IMPROvER finally published!!! First first authorship together with @Steve_Harborne and @JessicaJCB_ 🍾 Give it a go and stabilise your most loved/hated membrane protein :) nature.com/articles/s4159…
#OPENACCESS: "In-Lipid Structure of Pressure-Sensitive Domains Hints Mechanosensitive Channel Functional Diversity" by Charalampos Kapsalis et. al. cell.com/biophysj/fullt… @PliotasGroup @Bela_Bode @mayue3691 @LeedsIMB @AstburyCentre @ScienceLeeds @StAndrewsBSRC
It started out as a 10 week rotation project looking at particle behaviour in the ice, over 1 year later we finished it! Thanks to lots of people @DavidKlebl @Bex_16 @MDarrow7 @Molly_Gravett @michkouros @DCFMonteiro and more.. biorxiv.org/content/10.110…
It's published! #ionchannels #kcnt1 #epilepsy @Beth_aimee_cole @RachelJ9908 @jeff_dddd @FishwickGroup @stemuench
Very proud to share the first #CryoEM studies by our @UoL_LICAMM @AstburyCentre #TRPC team: Cryo-EM structures of human TRPC5 reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site. biorxiv.org/content/10.110…
We’ve got an exciting #postdoc opportunity working on #membraneprotein #structuralbiology in close collaboration with @LarsJeuken @PliotasGroup and Dr Antreas Kalli! Check it out here and please encourage anyone that could be interested to apply: jobs.leeds.ac.uk/vacancy.aspx?r…
Excited to announce that the Goldman Lab will be coming to Public Engagement Events Near You in March 2020 #AstburyConversation20 #BeCurious20
A cryo-EM grid preparation device for time-resolved structural studies doi.org/10.1107/S20522…
New publication from Integrative Membrane Biology by @PliotasGroup and @DrJonLippiat
New publication from Integrative Membrane Biology by @PliotasGroup and @DrJonLippiat
Great cover image by Dario de Vecchis and @antreaskalli group for their study on Band3 featured in Biophysical Journal @AstburyCentre @LeedsIMB
our final year @wellcometrust phd student ROTOR thesis!! Congratulations @brendanfarrell #thesistheend

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Tomasz Drobkiewicz @DrobkiewiczT
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Biophysical Journal @BiophysJ
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Instruct-ERIC @instructhub
5K Followers 4K Following Instruct-ERIC is a pan-European distributed research infrastructure making high-end technologies and methods in structural biology available to users worldwide
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474 Followers 556 Following Molecular dynamics simulations and modelling of membrane proteins with @AstburyCentre and @UoL_LICAMM. Managed by group members.
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