Neural Stem Cell Research Lab @NSCRLab
🧠 Modelling neurodegenerative diseases 💼 Job openings National Neuroscience Institute Singapore Joined August 2022-
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Check out our latest study on the effects of itanapraced on #Parkinsons disease! Thanks @mnt for the feature 👍🏼
Check out our latest study on the effects of itanapraced on #Parkinsons disease! Thanks @mnt for the feature 👍🏼
Upcoming @devbio_sg virtual seminar by Associate Professor Quenten Schwarz on interneuron development, happening on 27 October! @phil1pingham @MonteiroLab @onsunlau_nus @NSCRLab @HongyanWang9 @Yusuke_Toyama @ReversadeLab @unisaresearch
Upcoming exciting @devbio_sg seminar by Anna Akhmanova on #microtubules! @phil1pingham @MonteiroLab @onsunlau_nus @NSCRLab @HongyanWang9 @Yusuke_Toyama @ReversadeLab
SCSS Symposium 2022: Registration is open - mailchi.mp/d04991d7e09c/s…
Thanks for the feature! @Ingentium_PD The APP intracellular domain promotes LRRK2 expression to enable feed-forward neurodegenerative mechanisms in Parkinson's disease. magazine.ingentium.com/2022/08/24/the…
An experimental therapy for Alzheimer’s disease can break a molecular loop and protect neurons in mouse models of Parkinson’s disease, hinting similar approaches could prove beneficial for this incurable neurodegenerative condition. @NSCRLab #Neuroscience fcld.ly/2ro163e
Annovis Bio @AnnovisBio has announced that the 1st patient in the Phase 3 clinical trial evaluating buntanetap (aka ANVS401, Posiphen) in early stage #Parkinsons has been dosed; The trial will enroll a total of 450 participants, treatment for 6 months irpages2.eqs.com/websites/annov…
An experimental treatment for Alzheimer’s disease can break a molecular loop and protect neurons in mouse models of #ParkinsonsDisease, suggesting similar approaches could prove beneficial for this incurable neurodegenerative condition. fcld.ly/j7bul55 @scisignal
A positive feedback loop between AICD and #LRRK2 drives #neurodegeneration and mitochondrial dysfunction in #ParkinsonsDisease but can be targeted with the experimental drug itanapraced, show experiments in mice from the Tan and Zeng labs. @mysgh @NSCRLab fcld.ly/ccrcssg
New paper from the @NSCRLab! They found that in cultured neurons & brain tissue from mouse models of #ParkinsonsDisease, LRRK2-mediated phosphorylation of APP increased the abundance and activity of the APP intracellular domain. 🧠 @scisignal bit.ly/3PGudRC
A self-sustaining molecular loop that drives Parkinson’s disease can be targeted in mice, new research answers a longstanding question about Wnt signaling, and more in this week’s new issue of Science Signaling. fcld.ly/q53lnia
We found that blood miR-150-5p was upregulated in #AlzheimersDisease #Dementia which could be a promising cost-effective and non-invasive biomarker for AD. Read our article published in @journal_ad! pubmed.ncbi.nlm.nih.gov/35811521/

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