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I was reminded by @kchonyc that it's been exactly 4 years to the day since we landed at @genentech. A lot has happened personally in that time, but the one constant has been how wonderful the journey with @PrescientDesign has been.
Gave my PhD dissertation talk! 🧬 Tried my best to make AI for drug discovery & protein design accessible for ML folks: Beyond lucky & grateful to have had @pabbeel @nc_frey @KevinKaichuang @PrescientDesign @berkeley_ai + many other collaborators & friends on this journey.🎈
We're hiring! 🎉 Join our @PrescientDesign @genentech team in NYC! We're hiring a Principal Software Engineer to lead the development of our flagship AI/ML Lab-in-the-Loop platform for therapeutic molecular design 🧬 Drive impact w/ full-stack skills (esp. front-end) as part of…
We're hiring! Come work with me, @timbitsz, and the fantastic teams @genentech Comp Bio / Disco Onc & @PrescientDesign as a postdoc. Link to apply below 👇
Congratulations to our cofounder @kchonyc for being the recipient of the Glen de Vries Chair of Health Statistics by @nyuniversity and @NYU_Courant!
Congratulations to our cofounder @kchonyc for being the recipient of the Glen de Vries Chair of Health Statistics by @nyuniversity and @NYU_Courant!
Lab-in-the-loop therapeutic antibody design At @PrescientDesign @genentech we have spent 3+ years reimagining drug discovery. We built a machine learning system to design and execute experiments. Here's how it works and what we can do 🧵 1/
stay tuned for more proper, detailed and exciting cover of this preprint, but whoa i'm so proud of the team @PrescientDesign and our achievements on <Lab-in-the-loop therapeutic antibody design with deep learning>!
We’ve started a new blog! 🎉 🫡 In the inaugural post,@keunwoochoi, Sr. Principal Scientist and Head of our LM team walks through how to scale model training using Torchdata and its multi-threaded parallelism.
We’ve started a new blog! 🎉 🫡 In the inaugural post,@keunwoochoi, Sr. Principal Scientist and Head of our LM team walks through how to scale model training using Torchdata and its multi-threaded parallelism.
Protein engineering in low-data regimes with pairwise representations A 🧵on our latest preprint: DyAb predicts binding affinity with high accuracy using as little as 100 training examples and generates designs with > 10x improved binding 1/
CDS PhD student @_angie_chen presents LLOME, using LLMs to optimize synthetic sequences with potential applications for drug design. Co-led by @samuel_stanton_ & @nc_frey and with insights from @kchonyc, @RichBonneauNYC, and others at @PrescientDesign. nyudatascience.medium.com/language-model…
Research Intern position @PrescientDesign in Switzerland 🇨🇭💊 join our Frontier Research team in 2025! Apply now or share with anyone who might be interested: roche.wd3.myworkdayjobs.com/roche-ext/job/…
[1/n] Does AlphaFold3 "know" biophysics and the physics of protein folding? Are protein language models (pLMs) learning coevolutionary patterns? You can try to guess the answer to these questions using mechanistic interpretability. But the thing is, more often than not, we know…
1/🧬 Excited to share PLAID, our new approach for co-generating sequence and all-atom protein structures by sampling from the latent space of ESMFold. This requires only sequences during training, which unlocks more data and annotations: bit.ly/plaid-proteins 🧵
we'll also hire 2025 summer interns for LLM product dev @PrescientDesign @genentech. it's taking time for the job description to be out, please feel free to share your resume & short intro to my `[email protected]` in the meantime.
we'll also hire 2025 summer interns for LLM product dev @PrescientDesign @genentech. it's taking time for the job description to be out, please feel free to share your resume & short intro to my `[email protected]` in the meantime.
My team at @PrescientDesign is hiring! 🎉 @keunwoochoi, @kchonyc, and I are looking for ML engineers to develop our internal LLMs & foundation models for drug discovery. Feel free to DM or reach out to us at #neurips2024! Link: tinyurl.com/prescient-llm
Say hi at @emnlpmeeting #EMNLP2024 ! Here in Miami to spread the good word about our job openings, look at tons of posters, and connect with old friends and new :)
we're still hiring fresh phd level MLEs for LLMs. roche.wd3.myworkdayjobs.com/ROG-A2O-GENE/j… as well as slightly seniors (LLMs) roche.wd3.myworkdayjobs.com/en-US/ROG-A2O-… and also infrastructure MLEs roche.wd3.myworkdayjobs.com/en-US/ROG-A2O-…
LLMs are highly constrained biological sequence optimizers. In new work led by @_angie_chen & @samuel_stanton_ , we show how to drive an active learning loop for protein design with an LLM. 1/

Sergey Ovchinnikov @sokrypton
16K Followers 4K Following Scientist, Assistant Professor @MITBiology, #FirstGen, ProteinBERTologist, 🇺🇦 No Human is illegal. Moving to: https://t.co/sow6IRD3jj
Kevin K. Yang 楊凱�... @KevinKaichuang
21K Followers 6K Following Principal Researcher in BioML @MSFTResearch (@MSRNE). He/him/他. 🇹🇼
Andrew White 🐦�... @andrewwhite01
27K Followers 2K Following Head of Sci/cofounder @FutureHouseSF. Prof of chem eng @UofR (on sabbatical). Automating science with AI and robots in biology. Corvid enthusiast
Noelia Ferruz @ferruz_noelia
5K Followers 755 Following Group leader at @CRGenomica. Generative models for protein design 🥼🧪💻. Mountain lover 🏃♀️🚵♀️
Stephen Ra @stephenrra
3K Followers 553 Following Senior Director of Generative AI for Drug Discovery & Founding Team @PrescientDesign • @genentech
Kyunghyun Cho @kchonyc
77K Followers 2K Following a combination of a mediocre scientist, a mediocre manager, a mediocre advisor & a mediocre physicist at @nyuniversity (@CILVRatNYU) & @PrescientDesign
Kresten Lindorff-Lars... @LindorffLarsen
15K Followers 2K Following Protein and coffee lover, father of two, professor of biophysics and sudo scientist at the #LinderstrømLang Centre for Protein Science 🇩🇰
Joseph Watson @_JosephWatson
3K Followers 99 Following Co-Founder @ Xaira Therapeutics Former Baker Lab PostDoc at @UWproteindesign. Interested in generative modelling for molecular design. Views my own.
Machine learning for ... @ml4proteins
8K Followers 124 Following Seminar series on machine learning for protein engineering. Details for seminars and slack are on our website. DM us if you're interested in presenting!
David Juergens @DaveJuergens
3K Followers 2K Following Machine learning for molecular design. Currently: Postdoc @StanfordUChem @mtzlab. PhD @UWMolES @UWproteindesign. B.S. @UWChemE
Ellen Zhong @ZhongingAlong
8K Followers 887 Following Assistant Professor @PrincetonCS. #ai4science #proteins247 #cryoem #cryodrgn ❄️🐉 Prev: @MIT @DeepMind @DEShawResearch. Currently moonlighting @generate_biomed.
Anshul Kundaje (anshu... @anshulkundaje
26K Followers 3K Following Federally funded academic research is the innovation engine of the US economy. Reform is welcome. Destruction will have long term consequences.
Michael Bronstein @mmbronstein
53K Followers 6K Following #DeepMind Professor of #AI @UniofOxford / Director #AITHYRA / Chief Scientist @vant_ai / https://t.co/kZpGpDzYeV (opinions are mine) 🤖🧪🧬🎶🐎
Nature Biotechnology @NatureBiotech
318K Followers 2K Following Publishing the best of biotech science and business. Find us on Bluesky, Facebook & Instagram. Part of @SpringerNature and @NaturePortfolio.
Gabriele Corso @GabriCorso
8K Followers 679 Following PhD student @MIT • Research on Generative Models and Geometric Deep Learning for Biophysics • BA @CambridgeUni • Former @TwitterResearch, @DEShawGroup and @IBM
Simon Batzner @simonbatzner
5K Followers 2K Following RS at GDM, interested in RL, physics, chess. prev: Google Brain
Roshan Rao @proteinrosh
3K Followers 571 Following he/him. Research scientist @EvoscaleAI. Foundation models for biology. Prev: RS @MetaAI, PhD @berkeley_ai.
Tom Sercu @TomSercu
2K Followers 755 Following Building @evoscaleai - Frontier AI for biology. Ex-Meta FAIR, Ex-IBM Research. Alum @NYU, @ugent.
Olexandr Isayev 🇺�... @olexandr
10K Followers 4K Following #CompChem Prof @CMU_Chem. Connecting chemical sciences with AI & #MachineLearning. #tarheels fan. Care:#design, #photography #Ukraine #cats🐈 Rants are mine
Samuel Stanton @samuel_stanton_
2K Followers 945 Following loading... | formerly @PrescientDesign @Genentech | @NYUDataScience PhD | developing AI agents for scientific discovery in biotech
Bolaji Micah @bolaji_micah
19 Followers 175 Following
Shivam Khandelwal @ShivamK22606887
3 Followers 110 Following
ema @EmaEma00766162
0 Followers 497 Following
mario liu @marioli75019666
2 Followers 98 Following
Rishikesh ⚒️ @redrodeo03
577 Followers 979 Following BITS Pilani, Goa • cloud architecture @deepforestsci • ex computational biologist @CSIR_CDRI • grand prize @iGEM Paris hackathon
c @minimal_system
0 Followers 1K Following
Su Ku @sukuya
100 Followers 2K Following
Conor Howard @conor_j_howard
50 Followers 260 Following Deep Mutational Scanning @OctantBio | protein biochemistry | RNAseq | structural biology | evolution
Prasasya @prasasyax
90 Followers 2K Following
Blingeria @Blingeriashop
20 Followers 1K Following High quality clothing and jewelry for a fair price
gjtsjc @gjtsjc
58 Followers 2K Following
Dhruv Ghulati @dhruvghulati
3K Followers 2K Following AI/ML Product Manager @uber | Exited founder @factmata (AI for misinformation online), @ForbesUnder30 @joinef. Tweet about #philosophy, #aiproduct, & #ai
Ben Lau @ben__lau
58 Followers 392 Following CS & Chemistry @swarthmore. MD-PhD @uncmdphd. Epigenetics, retrotransposons, functional genomics.
adiba.eth @re_develop
430 Followers 4K Following I'm interested in tech stuff, network states, startups, coffee, #bitcoin, #ethereum and web3 (📖, 🖊, 🔑)
Helio Jimenez @Helija92
114 Followers 2K Following
chang ma @ma_chang_nlp
772 Followers 1K Following Ph.D student @hku previously @PKU1898, I work on agents and science.
Jeremy C. Tran @jeremyctran
112 Followers 586 Following Biomedical Engineering PhD Student at Boston University
Michael Rose @mrose00
108 Followers 2K Following
Nahum Maru @nahuum_maru
128 Followers 460 Following research @cartesia_ai @arcinstitute | prev @stanford @microsoft @hazyresearch
Piyush Nanda @NandaPiyush
317 Followers 860 Following PhD candidate @Harvard Prev. @IITKgp Fascinated by the regulation and evolution of metabolism & biomanufacturing I make 7 figures...for my research articles
Moon @mnagai_
82 Followers 290 Following PhD student at Koo lab @CSHL | Computational Biology | AI Alignment
Pourya Kalantari @kalantari11
515 Followers 1K Following
June Park @drjunepark
142 Followers 193 Following Building in biotech 🧠 exploring how the world works. @CFR_org TM, ex @The_Termeer_Fdn @Gates_Cambridge @MIT BS @Cambridge_Uni PhD.
Omar Abudayyeh @omarabudayyeh
8K Followers 3K Following @harvardmed Asst. Professor | researcher in genome editing, AI, and aging | @MIT @broadinstitute | Co-founder @Sherlock_bio & https://t.co/GnLoSm96Rz & Tome Bio
matt @hemattologyy
315 Followers 3K Following synthetic biologist building genetic and protein circuits for cancer and the software to design them
Filippo Caschera @Stjle
475 Followers 774 Following Synthetic Biology, Artificial Cells, Amphiphile Systems, Machine Learning, Cell-Free Protein Synthesis: Italy, Denmark, Japan, USA, France, Germany, UK.
云创兽Ai @Awjukui757063
1 Followers 118 Following 📊 analyzing macro trends lover, growing girl! excited for stock picks. DM me about global ETFs! 🔥 #Nasdaq #Stocks
jonhy @xdz9613
4 Followers 246 Following
Steph. S. @sts_1990
549 Followers 7K Following
Edmund Miller @E_Miller88
150 Followers 1K Following @[email protected] https://t.co/f7DNFGWtLu https://t.co/aplCuY5GJA
stann @longrmb
516 Followers 4K Following growing human creative output exponentially one nudge at a time
Belen Sotomayor @BelenSotomayor5
366 Followers 560 Following Ph.D candidate @Cornell | #Synbio @DeLisaGroup | Biotech leader @GlobalBRev @ALLBIOTECH | Chemical Engineer | #Ecuador
Quantum Daddy @LegalPrimes
1K Followers 5K Following ⚛️🔧🥷🏽🦄 Financial primitives & exotic derivatives Founder @OG_Financial
Rut christine @ChristineR2303
6 Followers 229 Following
Antonio Pérez @antoniopeva
3 Followers 40 Following
Stephen Ra @stephenrra
3K Followers 553 Following Senior Director of Generative AI for Drug Discovery & Founding Team @PrescientDesign • @genentech
Kyunghyun Cho @kchonyc
77K Followers 2K Following a combination of a mediocre scientist, a mediocre manager, a mediocre advisor & a mediocre physicist at @nyuniversity (@CILVRatNYU) & @PrescientDesign
Samuel Stanton @samuel_stanton_
2K Followers 945 Following loading... | formerly @PrescientDesign @Genentech | @NYUDataScience PhD | developing AI agents for scientific discovery in biotech
Josh Rackers @JoshRackers
1K Followers 581 Following Always Dada, sometimes a scientist, occasionally funny.
Nathan C. Frey @nc_frey
4K Followers 1K Following In the arena | Ex-@PrescientDesign • @Genentech | Advisor @atomscale & @guidelabsai | @MIT, @Penn PhD, @BerkeleyLab
Frances Ding @FrancesDing
275 Followers 120 Following PhD student in EECS, UC Berkeley. ML fairness and interpretability. ML for protein design.
Mingyu Derek MA @mingyu_ma
423 Followers 920 Following Senior ML Scientist @Genentech @PrescientDesign. PhD @UCLA. Fellowship @jpmorgan, @amazon. Working on Language Models and agents for biomedicine and science.
Angelica Chen @_angie_chen
2K Followers 464 Following Gemini training @ GDM PhD from @NYUDataScience, previously @Princeton 🐅 angie-chen at 🦋 Interested in LLMs, pastries, and running
Sabrina J. Mielke @sjmielke
4K Followers 591 Following #NLProc ∩ #ML @PrescientDesign @Genentech ␥ 💻🧩🔡🔬🏳️🌈 ␥ she/her
Tyler Bryson @tyler_a_bryson
46 Followers 18 Following
Vishnu Sresht @VishnuSresht
141 Followers 359 Following Director @PrescientDesign • @Genentech // Previously: @Pfizer, @MIT, @iitbombay
Omar Mahmood @omarnmahmood
157 Followers 58 Following ML Scientist at @PrescientDesign | PhD from @NYUDataScience
Changpeng Lu @ChangpengLu
17 Followers 74 Following
Sidney Lisanza @sid_thesci_kid
1K Followers 677 Following amateur scientist @PrescientDesign ; recovering grad student @UWproteindesign ; solidarity with the global south 🇰🇪
Karolis Martinkus @KarolisMar25650
14 Followers 8 Following
Amy Lu @amyxlu
4K Followers 2K Following Senior Research Scientist @IsomorphicLabs building AI for drug discovery. Prev: CS PhD @berkeley_ai, @PrescientDesign, @insitro, @UofT. 🇨🇦
Clara Fannjiang @clara_fannjiang
379 Followers 94 Following Senior ML Scientist @PrescientDesign @Genentech. @Berkeley_EECS Ph.D., formerly @GoogleAI @MBARI_News. science is only a glimpse into the genius of God.
pan tom @daspantom
115 Followers 314 Following
Bodhi Vani @bodhivani
424 Followers 126 Following ML/statmech/biophys @PrescientDesign. Ex @tiwarylab @IPST, PhD @ Dinner Group @UChicago, @IITB. Likes molecules jiggling and wiggling on manifolds.
Matthieu Kirchmeyer @m_kirchmeyer
202 Followers 873 Following ML Scientist @Genentech | @PrescientDesign
Anupriya Tripathi @anupriya_trip
812 Followers 223 Following Principal ML Scientist @PrescientDesign @genentech | PhD @UCSanDiego | BTech @iitroorkee | #FirstGen | discovering cool small mols
Pedro O. Pinheiro @pedroopinheiro
255 Followers 1K Following
kangway chuang @kangway
494 Followers 333 Following Principal AI Scientist at Prescient Design / Genentech. I lead a group that solves problems in drug discovery with machine and deep learning. he/him
Max W. Shen @maxwshen
1K Followers 480 Following wandering and wondering. Research Scientist at Prescient Frontiers Research, Genentech. Forbes 30u30 Science.
Amy Wang @amywang01
367 Followers 330 Following Sr ML Scientist @PrescientDesign working on problems at the intersection of strxbio, physics, and machine learning. prev @Stanford @MSFTResearch @MIT
Keunwoo Choi @keunwoochoi
6K Followers 839 Following Foundational Models @genentech, Advisor @gaudiolab, Adjunct Professor at @KAIST. AI, music, language. Prev: @tiktok_us @spotify, @c4dm @qmul.
Namuk Park @xxxnell
646 Followers 439 Following Postdoc @PrescientDesign @Genentech 🤖 🧬 / ❤️ Transformer, representation learning, uncertainty, computational biology, ML for Science
Guadalupe Gonzalez @justguadaa
473 Followers 494 Following Machine Learning Scientist @PrescientDesign | @Genentech | @Roche. @ImperialCollege PhD
Aya Abdelsalam Ismail @asalam_91
493 Followers 219 Following Co-founder and CSO @guidelabsai Former Research Scientist @prescientdesign @Genentech, PhD @umdcs
Arian Jamasb @arian_jamasb
909 Followers 511 Following Tensor jockey @PrescientDesign PhD @Cambridge_Uni | ML, Drug Discovery & other buzzwords | Prev @EPFL @Mila_Quebec @TheTeamAtX @relationrx @flyconnectome
Natasa Tagasovska @tagasovska
413 Followers 219 Following Principal Machine Learning Scientist @PrescientDesign | @Genentech | @Roche
Julius Adebayo @juliusadml
2K Followers 1K Following Building @guidelabsai - Engineering interpretable models and agents that are easy to audit.
Franziska Seeger (she... @FranziskaSeeger
1K Followers 988 Following Scientist @PrescientDesign @Genentech | former @UWProteinDesign @Amazon @NovoNordisk | obsessed with 👩🏼🔬🏔🏃🏻♀️🚵🏽♀️🐶 🐎⛷🧘🏻♀️📚
Ed Wagstaff @EdWagstaff
463 Followers 511 Following
Joshua Yao-Yu Lin @joshualin24
490 Followers 1K Following Machine Learning Scientists at Prescient Design/Genentech. Advancing Science with ML. Prev at Google Research, Flatiron Institute, and UIUC. Physics PhD
Henri Dwyer @HenriDwyer
187 Followers 186 Following Machine learning @PrescientDesign, @Genentech. Ex @Lyft and @Facebook
Andreas Loukas @loukasa_tweet
2K Followers 485 Following machine learning biology. doesn't work on LLMs yet. likes to think about how machines learn
Ji Won Park @jiwoncpark
877 Followers 1K Following Principal ML Scientist at @Genentech @PrescientDesign. Bayesian optimization, Bayesian inference.
Genentech @genentech
125K Followers 227 Following Official Twitter for Genentech. See our community guidelines here: https://t.co/yas51FPhKU
Andrew Watkins @amw_stanford
588 Followers 747 Following Protein designer, @genentech/@PrescientDesign. Formerly Stanford (RNA biochemistry and biophysics), NYU (peptidomimetics).
VGligorijevic @GligorijevicV
408 Followers 165 Following Founder & Senior Director of AI/ML @PrescientDesign @genentech (gRED)