Mitchell Center for AD (Claudio Soto Lab) @Proteopathy_Lab
A translational&interdisciplinary research center at @McGovernMed developing novel diagnostic tools & therapeutics for protein-misfolding-diseases med.uth.edu/neurology/spec… Neurology, UTHealth, Houston Joined March 2021-
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Following1K
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We are #HIRINGNOW #postdocs with #Biochemistry #biophysics experience! Project involves #STEMcells #singlecell #multiomics #CryoEM for #Parkinsons #research. DM for more info or use link below: linkedin.com/posts/mitchell… #Parkinson #tau #STEM #postdocjobs #protein
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Mitchell Center for AD (Claudio Soto Lab) retweeted
Just out in @TheLancetNeuro — our review of neuropsychiatric features of #Parkinsons @movedisorder @UCLMentalHealth @UCLBrainScience @MDC_IoN_UCL thelancet.com/journals/laneu…
We had a #Christmas event after two years!! Fabulous Brazilian Steakhouse lunch at Casa do Brazil! #MerryChristmas to everyone and #HappyHolidays! Stay Safe everyone! #AcademicTwitter #Christmas2021 #biology
Mitchell Center for AD (Claudio Soto Lab) retweeted
Together with @AnoopArunagiri and other colleagues we launch frontiersin.org/research-topic… Looking forward for your contributions on multiple flavors of #Protein_homeostasis; #Protein_aggregates; #Phase_separation; #Protein_condensates; #Amyloids and #Proteotoxicity among others!
Mitchell Center for AD (Claudio Soto Lab) retweeted
Biomarker of synapse dysfunction [neuronal pentraxin 2 NPTX2] in CSF is the first to change in familial frontotemporal dementia #FTD ahead of #NFL and neuroinflammation markers 👍to Emma van der Ende and GENFI team DOI: 10.1093/brain/awab382 @Brain1878 @GENFI1 #SynapticHealth
Mitchell Center for AD (Claudio Soto Lab) retweeted
Spatial transcriptomics at subspot resolution with BayesSpace go.nature.com/3gd7nBw
Mitchell Center for AD (Claudio Soto Lab) retweeted
First author @edward130603 goes #behindthepaper on a tool for clustering analysis and resolution enhancement of spatial transcriptomics data bioengineeringcommunity.nature.com/posts/spatial-…
Mitchell Center for AD (Claudio Soto Lab) retweeted
🧵 One of the most asked questions about #ParkinsonsDisease is: what are the symptoms? Here are some fast facts to help keep you informed. Was there anything listed here you hadn’t heard of before? Let us know in the replies! (1/2) #tremor #insomnia #neurotwitter #neurology
Interesting finding with pretty vast implications
Interesting finding with pretty vast implications
Mitchell Center for AD (Claudio Soto Lab) retweeted
A multi-step nucleation process determines the kinetics of prion-like domain phase separation: nature.com/articles/s4146…
Mitchell Center for AD (Claudio Soto Lab) retweeted
Simultaneous Detection of Six Isoforms of Tau Protein in Human Cerebrospinal Fluid by Multidimensional Mass Spectrometry-Based Targeted Proteomics pubs.acs.org/doi/10.1021/ac…
Mitchell Center for AD (Claudio Soto Lab) retweeted
A new work from our lab (in collaboration with many exceptional labs at @WUSTLmed) by @Da_Mesquita_S (now PI @MayoClinic), attempting to link #MeningealLymphatics to human Alzheimer's (please read the supplemental figures - a lot of cool data there!) || nature.com/articles/s4158…
Mitchell Center for AD (Claudio Soto Lab) retweeted
Does Alzheimer’s disease pathology spread through the brain consistently across the population? We delve into this in our paper “Four distinct trajectories of tau deposition identified in Alzheimer’s disease”, now online at Nature Medicine. nature.com/articles/s4159… Thread below 1/
Mitchell Center for AD (Claudio Soto Lab) retweeted
and here is our simple web browser developed by Patricia Losada to look up the expression of your favorite gene in the human brain vasculature and in AD twc-stanford.shinyapps.io/human_bbb/
Mitchell Center for AD (Claudio Soto Lab) retweeted
Congrats @andcyang RyanVest @fabiankern13 to human brain vascular map & role in AD in collaboration with @SiegenthalerLab and Andreas Keller biorxiv.org/content/10.110…. Discovered 2 types of pericytes, one differentially lost in AD, PV fibroblast types & tie AD GWAS to vasculature
Mitchell Center for AD (Claudio Soto Lab) retweeted
"#Parkinsons disease is evolving from a clinical to a biomarker-supported diagnostic entity, for which earlier identification is possible, different subtypes with diverse prognosis are recognised, & novel disease-modifying treatments are in development" thelancet.com/journals/laneu…
Mitchell Center for AD (Claudio Soto Lab) retweeted
Congrats @SingletonNeuro, well deserved ... now you get to drop “acting” director from your email signature 🦾 #CARD nia.nih.gov/news/dr-andrew…
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