Sayed Abdel-whab (ORCID: 0000-0003-2103-0922) @Sayedabdelwhab
V: for Virus, Virulence, Vaccine Head of Avian Influenza Lab, FLI, Riems, Germany Priv.-Doz., Habil, Giessen Uni. Cert. Virologist Editor-in-Chief npj Viruses Isles of Riems, Germany Joined February 2011-
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Landscape changes elevate the risk of avian influenza virus diversification and emergence in the East Asian–Australasian Flyway | PNAS pnas.org/doi/full/10.10…
HUGE outbreak of HPAI in Norwegian seabirds, w "environmental contamination" of sheep grazing areas. 1/220 sheep tested positive by serology. 👉biorxiv.org/content/10.110…
Alina Tscherne from my lab in Vienna wrote a really comprehensive overview of mucosal COVID-19 vaccines in clinical development. Open Access: sciencedirect.com/science/articl… @MedUni_Wien
My habilitation thesis is now available in German university libraries & soon online! Grateful to all mentors, collaborators & funders!
🎓 In my lab, on the island of Riems, we’re hiring a doctoral student (m/f/d) for 4 years! Join our innovative DFG-funded project ImmunoChick 2.0. 📅 Deadline: 25-08-2025 | Start: 01-10-2025 More info & apply 👉 fli.de/en/career/vaca…
do you know how expensive that car is?
Happy to announce that the DFG continues to support @ImmunoChick 2.0! Excited to advance innovative research on the avian immune system to improve vaccines, animal health, and zoonosis prevention. 🐔🔬 #ImmunoChick #DFG #AvianImmunology
🚨 Duck-origin H5N6 bird flu in China shows stronger binding to human receptors and resists current poultry vaccines. A rising threat to public health. 🦆🧬 #AvianInfluenza #H5N6 #OneHealth sciencedirect.com/science/articl…
nature.com/articles/s4158… Wow! 1,700 transgenic mice for the most comprehensive enhancer characterization ever. Leo and Axel never cease to amaze!
Very happy that our paper on the receptor binding properties of contemporary H3N2 viruses is now published @CellReports #glycotime cell.com/cell-reports/f…
biorxiv.org/content/10.110… Viral diversity makes the jump but then shrinks fast! New study shows influenza A’s transmission bottleneck happens after infection starts, not during transfer. Host factors may play a bigger role than we thought. 🦠🔬 #FluEvolution #ViralTransmission
Surprise alert! Unexposed people carry low-level antibodies that can fight H5N1. Could this be a hidden shield against the next flu pandemic? 🦠💪 #H5N1 #FluImmunity #PandemicPrep biorxiv.org/content/10.110…
New remote swabbing tool lets researchers safely sample Antarctic seals--> cutting stress, risk, and costs while boosting wildlife disease monitoring in harsh polar conditions! biorxiv.org/content/10.110…
Reinstating RIG-I in chickens sparks a stronger immune response but worsens flu outcomes, shedding light on why chickens lost this gene in evolution to avoid damaging inflammation. 🐔🦠 #AvianImmunity #RIGI #Influenza biorxiv.org/content/10.110…
biorxiv.org/content/10.110… H7N7 LPAIV infection in point-of-lay hens offers partial protection but doesn’t stop HPAIV spread, highlighting risks of silent virus emergence on layer farms. 🐔🦠 #AvianInfluenza #H7N7
A live NS1-deficient flu vaccine shows promise in protecting against cattle-origin H5N1 viruses spreading in the US. One nasal dose protected mice from deadly infection. nature.com/articles/s4154… #H5N1 #FluVaccine #OneHealth
H5N1 (B3.13) in dairy cattle: study with $950 per cow estimate... 20% of c.3500 herd symptomatic. Random sampling showed 90% seropositive (40% in dry cows). So 75% of infections *missed* by clinical diagnosis. Milk loss & death, esp. among symptomatic. nature.com/articles/s4146…
Crows infected with HPAI have limited disease signs, except ruffled feathers and some signs of mental confusion (virus in brain+trachea). All contact crows w no disease signs (low levels of RNA). All infected and 5/6 contact crows seroconverted @ 14 dpi 👉meridian.allenpress.com/avian-diseases…
Cool opportunity for a PhD student to work on avian influenza and avian viromes in Sweden. Should be a super fun project working on an amazing 20 year sample set from Mallards. 👉lnu.se/mot-linneunive…
🦠 How does flu hijack your cells? New study in npj Viruses @NaturePortfolio shows how influenza A virus protein NS1 sabotages our gene expression by targeting nuclear speckles, shutting down host mRNA production from the inside. nature.com/articles/s4425…
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