Jay Zhao @Shijie_Zhao
Microbiome, Microbial Genetics, Single-cell, Spatial Sequencing, high-throughput microbiome methods. Postdoc@Broad, PhD@MIT shijiezhao.github.io Cambridge, MA Joined July 2015-
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Jay Zhao retweeted
H3K4me3 is a post-transcriptional histone mark | bioRxiv biorxiv.org/content/10.110…
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Jay Zhao retweeted
I read this Cell paper that argues to have discovered a molecule (betaine) that mimics the geroprotective effects of exercise. This is a very valuable multi-omics resource, but the authors seemed to get caught in the rabbit hole of chasing a high-impact narrative🧵
Jay Zhao retweeted
This rate of validation suggests that affinity reagents such as antibodies should be considered non-specific until proven otherwise: 357 validated antibodies out of 1,124 tested. .
Jay Zhao retweeted
Grateful to work with the wonderful @Vilcek Foundation and the super talented @HIROKI_OTSUKA on a short manga highlighting our research and my journey as an immigrant scientist! 🧪🦠🧬 vilcek.org/news/microbes-…
Jay Zhao retweeted
Good news. After 2 rounds of venetoclax, GO, + chemo, my daughter has had a complete response. No detectable signs of the tumor that had completely shut her eye, which she was dangerously close to losing. 🙏🏾 to the amazing team @StJude & the community for helping us get here.
Jay Zhao retweeted
1/ Still using read.csv() to load big files in R? That’s like trying to fill a pool with a teacup. Here’s how to go 40x faster.
Jay Zhao retweeted
She nailed it!
Jay Zhao retweeted
I'm late to review the "Illusion of Thinking" paper, so let me collect some of the best threads by and critical takes by @scaling01 in one place and sprinkle some of my own thoughts in as well. The paper is rather critical of reasoning LLMs (LRMs): x.com/MFarajtabar/st…
I'm late to review the "Illusion of Thinking" paper, so let me collect some of the best threads by and critical takes by @scaling01 in one place and sprinkle some of my own thoughts in as well. The paper is rather critical of reasoning LLMs (LRMs): x.com/MFarajtabar/st…
Jay Zhao retweeted
Just published! Even NASA cleanrooms—designed to be ultra-clean—harbor resilient, novel bacteria. 26 new species were found, some forming biofilms, resisting radiation, and producing biotech-relevant compounds. Check it here: microbiomejournal.biomedcentral.com/articles/10.11…
Jay Zhao retweeted
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Bioeng Custom Lab Hardware Turn Key Genetic Design Please RT 💚
Jay Zhao retweeted
Editing 14 genes is no small feat, but I am not seeing enough evidence that "it is a dire wolf". Our community needs to communicate better to the public, now mor than ever, and imo that includes not exaggerating what we can deliver.
Editing 14 genes is no small feat, but I am not seeing enough evidence that "it is a dire wolf". Our community needs to communicate better to the public, now mor than ever, and imo that includes not exaggerating what we can deliver.
Jay Zhao retweeted
Jay Zhao retweeted
In 1999, I was assigned to design the expansion pack to Age of Empires 2. I chose The Conquerors as the theme, and wishing to have 4 civs (as we had on Rise of Rome), I chose the Spanish, the Aztecs, the Huns, and the Mayans. The project went ahead extremely well. We were…
Jay Zhao retweeted
When another failed biotech CEO tells you, “The best use of our remaining cash is to invest in our preclinical pipeline.”
Jay Zhao retweeted
PDF parsing is solved (again). Mistral's new OCR API — parses 1000-2000 pages for $1 — achieves state of the art results on tables, multilingual — supports structure: images, bounding boxes, scans, equations 90% of the world's organizational data is in PDFs.
Jay Zhao retweeted
Directed evolution at its finest. Altering TEV protease specificity. biorxiv.org/content/10.110… Congrats! @CarlDenard
Jay Zhao retweeted
What the actual fuck. Cursor just one shot this entire implementation. Getting Cursor to plan thoroughly based on your requirements is a game changer. plan.mdc file I used in comments.
Jay Zhao retweeted
So we beat on. Gene/cell therapies often use proteins that could be recognized/rejected as non-self by our immune system. We combine algorithms to build proteins that are therapeutically relevant and can masquerade as our own parts doi.org/10.1101/2025.0…
Jay Zhao retweeted
Roche SBX preprint out biorxiv.org/content/10.110…
Jay Zhao retweeted
We've started IND-enabling studies on a small molecule corrector for Rho-associated autosomal dominant retinitis pigmentosa (Rho-adRP). I thought it would be fun to spend some time walking through our approach and why we are excited. Long 🧵1/
Sudarshan A. Shetty (... @gutmicrobe
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Jonathan Eisen @phylogenomics
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Herbert R. Sim @HerbertRSim
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InferenceDomains.com @InferDomCOM
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Lior Pachter @lpachter
47K Followers 2K Following Bren Professor of Computational Biology @caltech. Blog at https://t.co/FFQzhEsmhi. Tweets represent my views, not my employer's. #methodsmatter
iMeta @iMetaScience
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Dmitri Petrov @PetrovADmitri
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Jack A Gilbert (he/hi... @gilbertjacka
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Sebastian S. Cocioba�... @ATinyGreenCell
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Science Magazine @ScienceMagazine
4.5M Followers 460 Following Cutting-edge research, news, commentary, and visuals from the Science family of journals. Follow @NewsfromScience for stories from our News team.
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35K Followers 426 Following Computational biologist @HelmholtzMunich, prof @TU_Muenchen & associate PI @sangerinstitute. Dad of 4 and mountain lover. Department news, see @CompHealthMuc
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nature @Nature
2.6M Followers 3K Following Research, News, and Commentary from Nature, the international science journal For daily science news, get Nature Briefing: https://t.co/wGmQlQ8a4D
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Xavier Lab @TheXavierLab
3K Followers 191 Following Genes to functions. Microbiome in health & disease. Computational biology. Chemical biology. Innate & adaptive immunity. https://t.co/fsw4zVpmOE
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X. Edward Guo 郭向�... @edguo84
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Bing Guan （管秉�... @bing_guan
2K Followers 3K Following Freelance photojournalist based in NYC. Contributor @reuters, @business, @nytimes, @wsj and others. Adjunct @columbiajourn. Views my own, RTs not endorsements.
Ping Mu 🇺🇦 @PingMu_PhD
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bioRxiv Synthetic Bio... @bioRxiv_synbio
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American Chemical Soc... @AmerChemSociety
263K Followers 1K Following The American Chemical Society is one of the world’s largest scientific societies and a leading source of authoritative scientific info.
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332 Followers 453 Following Accidental systems biologist, fan of metabolism, Postdoc in Marian Walhout Lab @UMassChan | PhD in Systems Biology @UMassChan | BS Fudan University
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128K Followers 597 Following Insert whatever credentials you think are important here - writer at @outkick author of ‘Unmasked’ and ‘Illusion of Control’
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Kulvinder Kaur MD @dockaurG
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Jennifer Sey @JenniferSey
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Vinay Prasad MD MPH @VPrasadMDMPH
313K Followers 4K Following These posts were issued before my FDA employment and do not necessarily represent the views of the FDA or the United States. The account is now inactive.
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Biology+AI Daily @BiologyAIDaily
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Alexandr Wang @alexandr_wang
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Molecular Plant & Pla... @MPlantPCom
13K Followers 454 Following Journals Publishing Exciting Research in Plant Sciences. https://t.co/TTlSiDg8q4 https://t.co/spbifLA9Nr
bioRxiv Plant Bio @biorxiv_plants
16K Followers 0 Following
Yulong Li Lab @yulonglilab
5K Followers 812 Following Yulong Li: PKU (BS, Beijing) - Duke Univ. (PhD, Durham) - Stanford Univ. (Postdoc, Palo Alto) - PKU (Prof. , Beijing)
Max Wilkinson @maxewilkinson
3K Followers 195 Following PhD @MRC_LMB, now post-doc at @MIT, dabbler in cryoEM. Keen on spliceosomes. Now also keen on reverse transcription. Kiwi.
Mary Elizabeth @meharpist
4K Followers 1K Following I’m a harpist and scientist, working as an editor for @nature when I’m not making music, biking or skiing. All views are my own.
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90 Followers 56 Following soccer, Harry Potter, oncology drug development, hard rock, catalyst, puppeteer
Linlin Fan @LinlinZFan
1K Followers 495 Following Assistant Professor @MIT, https://t.co/xtJMaRvRAq, Recruiting, Postdoc @Stanford, PhD @Harvard, feminist, all-optical physiology, learning and memory
Menglei Shuai @MengleiS
66 Followers 104 Following Interested in human microbiome, multi-omics and computational medicine | Postdoc | Broad Institute of MIT and Harvard @TheXavierLab
. @ChasingMicrobes
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