Soumik Ray @SoumikRay5
Assistant Professor at DTU, Denmark 🇩🇰, Ph.D. from IITB 🇮🇳, Postdoc from DTU 🇩🇰, Interests: Neurodegenerative diseases, biomolecular condensates buelllab.org Denmark Joined April 2019-
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PhD position alert 🚨. I have a fully funded PhD position in my group at DTU-Bioengineering. If you want to work with protein phase separation and aggregation in neurodegenerative diseases, this could be a great opportunity for you. Apply here: efzu.fa.em2.oraclecloud.com/hcmUI/Candidat…
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Soumik Ray retweeted
Synthetic biomolecular condensates enhance translation from a target mRNA in living cells: nature.com/articles/s4155…
Soumik Ray retweeted
Our new preprint on stability of alpha-synuclein fibrils and their disaggregation by chaperones is out!! The chaperones effectively disaggregate 3/4 fibril types with varying efficiencies that correlate with their thermodynamic stability. biorxiv.org/content/10.110…
Soumik Ray retweeted
I arrived in Tokyo to reunite with my better half @SamratLabMohali after 1.5 months & excited to see our latest paper published in @JPhysChem in which we show protein aggregation/disaggregation by Hofmeister cations. Congrats, @Deepika_MBLab @TIETofficial. pubs.acs.org/doi/10.1021/ac…
Soumik Ray retweeted
Our latest preprint is now live on bioRxiv! We demonstrate how to control α-synuclein adsorption, desorption, and aggregation at charged biomolecular condensate interfaces. Check it out here: doi.org/10.1101/2024.1…
Soumik Ray retweeted
Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag: nature.com/articles/s4146…
Soumik Ray retweeted
Want to measure the volume fraction of biocondensates or coacervates? We present easy and accurate methods, with which we found that upon destabilization, condensates can either shrink or swell, giving insight in condensate volume regulation in cells. chemrxiv.org/engage/chemrxi…
Soumik Ray retweeted
Check out our newest publication on creating custom architectures inside biomolecular condensates - congratulations Nadia, @DaoyuanQian219, Tomas and others together with the Weitz lab and @vanhest_lab! nature.com/articles/s4428…
Soumik Ray retweeted
Our paper on swimming active protein droplets is finally out! 🎊🎉 nature.com/articles/s4146… The main result is in the title: "Phase-separated droplets swim to their dissolution". Explanations below 🧵👇 @SoftLiv_Cornell @ETH_Materials @Cornell @CNRSingenierie @NatureComms
Soumik Ray retweeted
THEY SAID WE COULDN'T DO IT........well, no one actually said that. But in our updated manuscript with @CasperGoverde, @GoldbachNico, and @befcorreia we show you can now design soluble analogues of membrane proteins with preserved functional features! biorxiv.org/content/10.110…
In this comprehensive review now published in @JChemPhys , Alex (@biophysics_dtu) and I highlight the recent advances in the experimental methods to quantitatively study biomolecular phase separation. Really happy to finally see it online! doi.org/10.1063/5.0190…
Soumik Ray retweeted
Phase Separation and Aggregation of α-Synuclein Diverge at Different Salt Conditions dlvr.it/T3YxSM
Soumik Ray retweeted
How do proteins mis-fold? New preprint led by @JAunstrup from @alexander_buell @biophysics_dtu group with MD simulations by Abigail Barclay. We combined experimental measurements of Φ-values with restrained simulations to study the TSE for fibril growth doi.org/10.26434/chemr…
Soumik Ray retweeted
Happy to share the publication of our paper in @Nature Conformational ensembles of the human intrinsically disordered proteome Work led by @GiulioTesei and @AnnaIdaTrolle. I'll post more later, but for now here is a link: nature.com/articles/s4158… and a short movie about the work
Soumik Ray retweeted
Exciting news! Our latest preprint on determining surface charge of condensates using microelectrophoresis is available to read now on @ChemRxiv! Check out the research by Merlijn here: chemrxiv.org/engage/chemrxi…
Soumik Ray retweeted
Terrific work by @DebalinaDatta1, @ambuja_n and @maji_lab showing p53 phase separation might regulate its life cycle and function. Thanks to @serbonline, @iitbombay, @BsbeIitb for support and @SenguptaKundan for STED microscopy biorxiv.org/cgi/content/sh…
Soumik Ray retweeted
A fascinating work is published today @Nature by Zhang & Zhang et al. on a serendipitous discovery of haemoglobin expression outside the RBC cells--in chondrocytes--and their critical role in keeping our cartilage alive under an oxygen-deprived environment.…
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