Synthetic Regeneration Laboratory at Columbia @SynRegLab
#SyntheticRegeneration & Systems Physiology Laboratory @Columbia | Engineering Tissue Healing through Systems Physiology WoappiLab.com Manhattan, NY Joined April 2022-
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Wonderful kickoff day to the @CSCIColumbia Retreat! Great to be submerged in outstanding science and community!
Fantastic talk by our very own PhD student, Jonathan at @CSCIColumbia 2025 retreat!
Excited for this brand new academic year; so many possibilities…
The New England Immunology Conference is open for registration! Great meeting for networking and discussions of cool science. Check it out 😊 Nov 15-16, 2025 in Woods Hole, MA Registration: eventsquid.com/mobileapp.cfm?… newenglandimmunology.org
Targeting ECM-producing cells with CAR-T therapy alleviates fibrosis in chronic kidney disease: @CellStemCell cell.com/cell-stem-cell…
Working with a great team to organize @KeystoneSymp #Fibrosis : Cross Organ Pathology and Clinical Development, this February! Join us to explore emerging research in Banff! keysym.us/KSFibrosis26 #KSFibrosis26
🥇 Today, NIH has released its implementation plan for incorporating gold standard science into everything we do. The plan incorporates the 9 tenets of gold standard science adopted by the U.S. Government and aligns with @HHSGov’s framework for achieving these principles.…
In the latest issue! Perturb-Multimodal: A platform for pooled genetic screens with imaging and sequencing in intact mammalian tissue dlvr.it/TMfBXz
What's the difference between Trm and exhausted CD8 T cells? Simone Park's new work dissects this important question. These cell types are often confused, but are ontologically and mechanistically distinct with implications for immunotherapy responses. biorxiv.org/content/10.110…
Our study on immune cell aging across tissue compartments that was part of the CZI @ChanZuckerberg networks for the human cell atlas is out! Longterm collaborations with @psimslab @YosefLab @teichlab @Cambridge_Uni @ColumbiaMed nature.com/articles/s4159…
A new special issue of Science explores the immune system at the molecular and cellular level and how it has evolved to govern multiple facets of human health. Learn more: scim.ag/41yfaSC
Excited to share our latest paper @naturemethods We present a high-throughput framework to map cellular interactions at ultra-high scale – broadly applicable from whole-organism immune response mapping to personalized therapy response prediction (1/4). nature.com/articles/s4159…
Check out our new preprint on a novel neuro-immune niche that underpins touch sensation.
Check out our new preprint on a novel neuro-immune niche that underpins touch sensation. https://t.co/NSq9ubj9GU
Our PerturbNet paper is the cover article for Molecular Systems Biology! The image depicts our genAI model that predicts how cellular perturbations—including chemicals, gene knockdown or overexpression, and protein mutation—shift single-cell gene expression. 🧵
I spent 1.5 years at MIT designing a new undergraduate program in Genetic Engineering. One of our theses in designing that program (which I’ll share more about soon; I'm writing a long essay about it) was that undergraduate students could be trained to be excellent genetic…
In vivo CRISPR screens offer a unique way to study gene function at scale🐁. In our new @NatureRevGenet article, Alessio Strano, @randall_platt, and I review current methods, experimental designs, and explore exciting future directions!nature.com/articles/s4157… @ETH_en @ETH_BSSE
Multi-parameter spectral flow cytometry panel for immune phenotyping of murine B and T cell responses biorxiv.org/content/10.110… @HWardemann
'Cross-tissue multicellular coordination and its rewiring in cancer' nature.com/articles/s4158…
1/6 Excited to share our latest preprint: "MORPH Predicts the Single-Cell Outcome of Genetic Perturbations Across Conditions and Data Modalities". 🔗 biorxiv.org/content/10.110… 🧵 👇 Here is what MORPH is in a nutshell!

Yvon Woappi @DrWoappi
2K Followers 605 Following Husband, dad, and at times professor @Columbia | Proud member of @SynRegLab #SyntheticRegeneration
Tina Termini @CterminiPhD
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Dr. Chrystal Ama Star... @drstarbird
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Santiago Correa 🏳�... @SantiCorreaPhD
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X. Edward Guo 郭向�... @edguo84
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Santiago Correa 🏳�... @SantiCorreaPhD
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Amanda Lund Lab @theLundLab
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StanfordMCP @Stanford_MCP
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