EOMESBiotech @TCRAnalyst
Science & biotech, l/s views, No investment advice, DYODD. Germany Joined July 2022-
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Very sad to learn about this loss. Will be remembered even when this microcosm of BioX will be long gone, RIP @Sports_bios
Very sad to learn about this loss. Will be remembered even when this microcosm of BioX will be long gone, RIP @Sports_bios
Aged well
$VKTX Viking Therapeutics Announces Initiation of Phase 3 Obesity Clinical Program with GLP-1/GIP Agonist VK2735 - Jun 25, 2025 ir.vikingtherapeutics.com/2025-06-25-Vik…
$NKTR that’s a hit! Overall ~23.5% delta. Low (mid) dose delta was 29% (!!!) which is absolutely a huge hit. I wonder if this is the dose they’ll take forward - there is significant mechanistic rationale for reaching an inverse dose response with IL-2 drugs, so lower could…
$IMMP Against historical controls in 1L NSCLC
$AFMD Sad story - the should have gotten rid of 24 a year ago. And push for heme with 13 and 28. The latter one would’ve definitely been worth a shot. Not the right time for this company. Burrowed some relevant cash in this project, but everyone (I hope) knew the risk. Learned…
This whole „better, Aplus drugs, real benefit, overused surrogates“ is the other side of a black-white bogus discussion. People really forget quickly how this profoundly cuts innovation: Biology and medicine is not that simple and predictable and you need several shots on one…
This whole „better, Aplus drugs, real benefit, overused surrogates“ is the other side of a black-white bogus discussion. People really forget quickly how this profoundly cuts innovation: Biology and medicine is not that simple and predictable and you need several shots on one…
Now we see what Prasad was after. Very sorry for my clinical colleagues in the US to have another embarrassment after RFKjr.
Now we see what Prasad was after. Very sorry for my clinical colleagues in the US to have another embarrassment after RFKjr.
$IMMP turns out numbers back then indeed strange - company which stated imbalance as massive confounder was right apparently! CPS<1 promising now.
$IMMP turns out numbers back then indeed strange - company which stated imbalance as massive confounder was right apparently! CPS<1 promising now.
$GPCR and $VKTX really doing well on Pfizer comments. Pretty sure this ultimately reflects the trend reversal in both, now with revived M&A dreams, data readouts, some competition gone (but beware Reta data) and macro tailwinds.
KRAS: from undruggable to THIS
KRAS: from undruggable to THIS https://t.co/OcymWrR5xl
A good day to add to $SPY shorts, stay long treasuries and hold the $XBI and small caps ffs
Another reason generalists lost and loose trust in biotech investments when these techbio guys erratically promote their businesses with massively misleading and frivolous predictions.
Another reason generalists lost and loose trust in biotech investments when these techbio guys erratically promote their businesses with massively misleading and frivolous predictions.
$VKTX-VK2735 All good comments in the thread I’m quoting. However- I think it is better to look at a different VKTX patent for insight - specifically- US Patent 2024/0239843 A1 dated Jul-18-24. In that patent Viking identifies a "compound 23” that after much research I believe…
$VKTX-VK2735 All good comments in the thread I’m quoting. However- I think it is better to look at a different VKTX patent for insight - specifically- US Patent 2024/0239843 A1 dated Jul-18-24. In that patent Viking identifies a "compound 23” that after much research I believe… https://t.co/VCJjMTKx2E
Agree here; recession odds now at 50%. Yields may hit new highs in coming weeks but $xbi already decouples - Market started to price in recession. When it fully does, things get wild. Generalists may soon rotate in for diversification and hedge, given the broad uncertainty, that…
Agree here; recession odds now at 50%. Yields may hit new highs in coming weeks but $xbi already decouples - Market started to price in recession. When it fully does, things get wild. Generalists may soon rotate in for diversification and hedge, given the broad uncertainty, that…
@fluffer9 Yes - the modification of the -COOH end of the C18 fatty acid chain to a phosphonate is the KEY modification in this patent vs Tirzp. - and likely the reason why -2735 has a longer T1/2 than Tirzp (and other GLP1/GIP in development) - Patent expiry 2042 - .. I recall there is…
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