The Ott Lab @TheOttLab
Melanie Ott's lab @GladstoneInst studying host-viral pathogen interactions. Tweets from lab members. Retweets are not endorsements. ottlab.gladstone.org San Francisco, CA Joined January 2018-
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.@TheOttLab is #hiring a Research Associate to contribute #bioengineering and molecular biology skills for ongoing #virology research. Learn more: bit.ly/3SqDxhc #ScienceJobs #ScienceCareers #Jobs
Explore emerging #HIVResearch #HIVCoinfection research with field leaders @KeystoneSymp HIV and (Re)Emerging Viruses: Aligning Lessons Across Pandemics, this April in Hannover! keysym.us/KSHIVPath24 #KSHIVPath24
Looking forward to a peaceful night! Finally submitted my R25 as a PI for #PUMAS. An amazing program that I’m honored to lead, with Melanie Ott @TheOttLab PUMAS is an education internship program supporting URM students from community colleges! @GladstoneInst #internship #URM
👩🔬 @katelyn_luo13 mastered the ins and outs of cloning huge plasmids 🧬 and got some exciting data this summer! She was part of @GladstoneInst PUMAS program and worked with Fran in the lab!👏
HOPE has an incredible community team and Tom Villa has gone above and beyond for HIV research! Check out the @SauDiversidade podcast ‘HIV From Chaos To Cure’ on Spotify! #hiv #aids #hivcure #uequalsu #hivadvocate open.spotify.com/episode/4D2Yeg…
Our favorite lab jokester🤡, @mirmkhalid, was featured @GladstoneInst!👏👏 👨🔬Learn more about his unique hobbies and journey in science below! 👇 gladstone.org/news/meet-glad…
👩🔬Ursula recently published her collaborative work on the ensemble-based conformational propensities of HIV-1 TAR RNA binding to Tat protein. The work revealed TAR, in its biologically active state, is energetically unfavorable!🧬 nature.com/articles/s4158…
🚨Check out our latest publication with Ik-Jung Kim from @EricVerdin and @BuckInstitute. 🥼Along with Yong-ho lee, @mirmkhalid, @irenechen_png, and Yini Zhang we report that SARS-CoV-2 ORF8 limits spike expression by retaining Spike in the ER. 👉doi.org/10.1016/j.jbc.…
Kris and @mirmkhalid's work was featured! 👏Look at these pretty images👇
Kris and @mirmkhalid's work was featured! 👏Look at these pretty images👇
Congratulations @irenechen_png ! Dr. Irene successfully defended her thesis + attended commencement on the same day! Now that's grad student efficiency!🎉🔬 @GladstoneInst @Gladstone_GO Check out some of her work: pubmed.ncbi.nlm.nih.gov/35839775/ pubmed.ncbi.nlm.nih.gov/35584773/
Ott lab represent!! @GladstoneInst soccer team is playing in our second season! Come out and cheer us on!
🚨New publication alert!🚨 Check out the 🧵from @ttaha801 about the role of NSP6 in BA.1 attenuation! This was a group effort involving @irenechen_png @hayashi_jen and Takako to get this across the finish line! 👩🔬👨🔬 @QBI_UCSF @GladstoneInst @UCSF
🚨New publication alert!🚨 Check out the 🧵from @ttaha801 about the role of NSP6 in BA.1 attenuation! This was a group effort involving @irenechen_png @hayashi_jen and Takako to get this across the finish line! 👩🔬👨🔬 @QBI_UCSF @GladstoneInst @UCSF
🚨New preprint alert! Check out our story on the role of macrodomain from NSP3 in viral replication. 🥼 @ttaha801 @rahulsurya85 @irenechen_png @GladstoneInst @QBI_UCSF @UCSF @fraser_lab @Ashworth_SF
🚨New preprint alert! Check out our story on the role of macrodomain from NSP3 in viral replication. 🥼 @ttaha801 @rahulsurya85 @irenechen_png @GladstoneInst @QBI_UCSF @UCSF @fraser_lab @Ashworth_SF
Check out Raif's vlog encouraging awareness of @HOPEforHIVCure's "block, lock, and excise" approach! 👨🔬👩🔬 Scientists in our lab and beyond are hard at work discovering new antivirals and technology to remove the virus from infected cells!🧪 👉youtube.com/watch?v=105XfK…
Check out our newest paper on HIV transcriptional regulation!👇 cell.com/cell-reports/f… Daniela found SYMD5 associates with Tat/TAR and activates HIV transcription by binding to its promoter. SYMD5 is a possible target for latency-promoting therapy!🥳@GladstoneInst @CellReports
Happy International Women's Day! 👩🔬The amazing women in our lab are making important discoveries in virus-host biology! 👏👏 @hayashi_jen @LudivineGrzelak @irenechen_png @rae_padget + Steph, Maria, Ursula, Chia-Lin, Daniela, Gabby, Veronica, Alia! 😍 @GladstoneInst
🗣️ BA1 Omicron variant transmissibility VS low death rate - Mélanie Ott
Harmit S. Malik @HarmitMalik
44K Followers 8K Following Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results). @HutchBasicSci @fredhutch @HHMINEWS He/him
Gladstone Institutes @GladstoneInst
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zara weinberg 🧪�.. @weinberz
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HOPE Collaboratory @HOPEforHIVCure
569 Followers 70 Following HOPE is an international collaboration of scientists and community working together towards a cure for HIV. Lead by @TheOttLab, @TheValenteLab and @ndhlovulab.
Dr. Erica L. Sanchez @elsanchez09
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Baldauf Lab @Baldauf_Lab
865 Followers 637 Following Young and dynamic research group @LMU_muenchen working on innate immunity against retroviruses and cancer; @baldauflab.bsky.social
Friedemann Weber (@fr.. @Friedemann1
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906 Followers 626 Following Viruses, Mosquitoes & Mass-Spec: what else? Systems Arbovirology! Join our international research group in Hamburg. @Hamburg @LIV @SystemsArbovirology
Rachel Padget @rae_padget
667 Followers 362 Following Scientist | cardiovascular biology🫀 | avid outdoor lover | gamer | B.S. @UCentralMO M.S. @MissouriState Ph.D. @VT_TBMH
Vanessa Van Doren @vvd186
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Ssebanja Joseph @joseph_ssebanja
319 Followers 2K Following Embrace humanity with open arms; in every act of kindness, we find the essence of our shared humanity. [email protected]
Eve @StaffordMo6990
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Sophia Teuschel @sophi0611
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Nadeen Chahine @NadeenChahine
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Anne Hahn @kuriosera
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Emma Touizer @EmmaTouizer
286 Followers 507 Following MRC DTP PhD student @UCLInfectImm studying HIV & SARS-CoV-2, loves a good B cell🔬🦠🌍🏳️🌈 she/her
The Guzzo Lab @ UTSC .. @GuzzoLabUTSC
617 Followers 445 Following Virologists, immunologists, and scientists in training. Fascinated with HIV infection. Committed to diversity and inclusion. 👩🏻🔬
Kagan Cavusoglu 🇧�.. @kagancavusoglu
17K Followers 2K Following 🔰Peaceful Warrior 🔰Entrepreneur 🔰Consultant 🔰Activist 🔰PhD candidate #Psychology researches on #Leadership #GenZ #Digitalization "Sufrì, aprendí, cambié"
Izabela Rezende @IzabelaMR
366 Followers 775 Following Virologist 🇧🇷→🇺🇸 Postdoc @StanfordMed - Pandemic Preparedness, Epidemiology & Phylodynamics #emerging #zoonotic #virus #infectious #diseases 👩🏻🔬🦠🍻
Pruthviraj Mahadeo Ch.. @P_M_Chavan
83 Followers 2K Following MSc Biotechnology Student @ Indian Institute of Science Education and Research, Bhopal. Virus, Vaccine, Antibody & Viral Immunology Enthusiast
priya goyal @goyal_priya26
15 Followers 586 Following #Ph.D student #Virologist #Host virus interaction #Regulation of host cell glycolysis in Influena virus infection #Open for Post-doctoral position
Guilherme Nobrega @nobrega_gm
57 Followers 163 Following Biologist | PhD candidate | MSc in Maternal Health | Baylor College of Medicine - TX/USA & University of Campinas - SP/Brazil | #DiversityInSTEM 🏳️🌈🇧🇷
giulia.sinatti @giuliasinatti
239 Followers 531 Following anthropology | ethnography | transdisciplinary research | Africa-Europe research | co-creation | healthcare | HIV | migration
Christine C. Ph.D. @Limbictweets
6K Followers 6K Following Clinical practice specialization: Psychodynamic Psychotherapy, Developmental trauma/epigenetics. CPTSD. LGBTQIA2S+ ally. Board chair non-profit. Cancer survivor
Li Wu @LiWu_UIowa
1K Followers 485 Following Virology Professor, Chair, Department of Microbiology and Immunology at the University of Iowa. Lab research focuses on basic HIV studies. All views are my own.
Gaby Bailey @Gaby_Bailey_6
70 Followers 106 Following PhD candidate in the lab of Prof. Ramesh Jasti @nanohoops | @NSF GRFP fellow | Co-president for @uoadse | Alumni from @Reed_College_
Evelyn Strickland @strickland_ev
485 Followers 273 Following PhD researcher in the @OWeinerLab at @UCSF | Interested in Neutrophil swarming and collective cell control systems | Scarf enthusiast | 🏳️🌈
Phd_seeker @seeker_phd
80 Followers 774 Following I am seeking PhD position in Biotechnology/Molecular biology/Virology
Naiha Ahmad @naiha_ahmad
58 Followers 149 Following PhD student at UAMS | Virology | Innate immunity | Virus-host interaction
Thomas A Premeaux @ThomasPremeaux
23 Followers 77 Following
Manvendra (Manu) Sing.. @manvendr7
2K Followers 419 Following I research regulatory activities of HERVs in human evo-devo & diseases. Now: Neuroscientist @mpi_nat Alumni: @Cornell @MDC_berlin @ccmb_csir Mostly outdoors!
Dayna @daynathenomad
273 Followers 240 Following MIT grad 🎓Former NASA engineer 🚀@MissiontoPsyche | Electronics Tech @SmallBatchA| 🇺🇸🇰🇬🇰🇿|🗣️🇫🇷🇷🇺🇯🇵 | Autistic/ADHD/PMDD | they/them 🏳️🌈🏳️⚧️
Alex Matía @alexmati.. @alex___me
152 Followers 450 Following Postdoc @StanfordMed | PhD graduate in poxviromics and bioinformatics @INIA_es-@CSIC | @czbiohub
Schwarzer Lab @Schwarzer_Lab
32 Followers 71 Following Virus Enthusiasts // HIV // Hanta // We work on the characterization of HIV latency. Since one virus is not enough to work with, we also look at Hanta virus.
cpassaes @cpassaes
195 Followers 722 Following Learning how to be a scientist and a mother of twins. Believe in the power of science and education. ❤🔬🐶🍷📸🇧🇷🇵🇹🇫🇷 Opinions are my own.
Johanna Leyens @JohannaLeyens
37 Followers 90 Following PhD Student @ViroSchindler @uktuebingen. Interested in virology and how viruses escape the immune system🦠
Rama Dajani @RamaDajani
32 Followers 104 Following Research Associate @MarsonLab Gladstone-UCSF Institute of Genomic Immunology
Alisa Dietl @alisa_dietl
76 Followers 123 Following 👩🏼🔬MD/PhD studies @TU_Muenchen | PostDoc @PelkaLab, Gladstone-UCSF Institute of Genomic Immunology🧬. Views are my own.
Longevity Explorer @LongevityExplor
1K Followers 4K Following
Laurel Skurko @laurelskurko
377 Followers 785 Following Working with entrepreneurial teams that apply technology in novel ways to optimize work and improve lives. @UCalifornia_IT. All tweets are my own.
Jason Yeung @jayeung12
348 Followers 2K Following MD/PhD student @utmbhealth interested in emerging viruses and data science | Former ballet dancer using dance data for advocacy
Tatiana Trifan #Count.. @trifan_tatiana
376 Followers 1K Following Life is full of surprises, but never when you need one. Completely allergic to any form of racism, sexism, genderism. #StandWithUkraine Views are my own
glendadventures @glendadventures
909 Followers 4K Following Dog & human behavior. Past artisan baker, farmer (grassfed/resto ag), Corporate America. PsA, PASC. Rescued senior Pyr/ACD/etc mix Whiskey. Tweets ours.
Zhang SY @ZhangSY375019
4 Followers 10 Following
小萌 @Sun93225
1 Followers 14 Following
Farjana Ahmed @FarjanaAR
37 Followers 146 Following Scientist at Clinical Virology lab, Institute of Environmental Science Research (https://t.co/jU9rdtbSX0) Living on Viruses as a Parasite 🦠🦠
Yaghku @yaghku
0 Followers 16 Following
Melina Winkler @Winkler_Melina
20 Followers 117 Following Postdoc @ExpVirology | interested in virus host interactions of RNA viruses
Arnab Bhattacharya �.. @Arnab28122000
125 Followers 850 Following Curious techie battling my way through blockers
Carolyn Bertozzi @CarolynBertozzi
78K Followers 3K Following Prof. @StanfordUChem; Baker Family Director, @Stanford_ChEMH; @HHMINews Investigator; EIC of @ACSCentSci; She/Her 🏳️🌈
Doudna Lab @doudna_lab
71K Followers 88 Following News from Jennifer Doudna's lab at @UCBerkeley @igisci. Tweets from lab members and not Jennifer Doudna unless signed JD. Tweets represent personal views only.
Eric Topol @EricTopol
694K Followers 589 Following physician-scientist, author, editor. Ground Truths: https://t.co/YhatcBT0hA
Harmit S. Malik @HarmitMalik
44K Followers 8K Following Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results). @HutchBasicSci @fredhutch @HHMINEWS He/him
Michael Eisen @mbeisen
77K Followers 15K Following I science & try to make science open. Tweets do not represent my employer's views, but are always correct. My conflicts of interest https://t.co/bZ7I9oSJe0.
Gladstone Institutes @GladstoneInst
13K Followers 4K Following Gladstone's mission is to drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an inspiring and diverse environment.
Benoit Bruneau @benoitbruneau
9K Followers 2K Following Cardiovascular disease researcher, developmental biologist, and Oakland resident. Je cherche a comprendre.
The Nobel Prize @NobelPrize
1.1M Followers 509 Following The official Twitter feed of the Nobel Prize @NobelPrize #NobelPrize
Adair Borges @AdairLBorges
2K Followers 2K Following Scientist @ArcadiaScience 🧬✨| Former @UCBerkeley Miller Fellow @BanfieldLab | PhD @joeBondyDenomy lab @UCSF | She/Her | #LGBTQSTEM 🏳️🌈
Patrick Hsu @pdhsu
30K Followers 3K Following co-founder @ArcInstitute, @BerkeleyBioE professor | researcher & investor in genome editing, biotech, AI | 🇨🇦 @harvard @broadinstitute @editasmed, Fast Grants
Marson Lab @MarsonLab
8K Followers 4K Following News from Dr. Alex Marson's lab @UCSF & @GladstoneInst, focusing on advances in immunology, CRISPR & genomics. Tweets represent personal views only.
Hani Goodarzi @genophoria
4K Followers 1K Following Core Investigator @arcinstitute | Associate Professor @Ucsf_Biochem @UCSFurology @UCSFCancer | {Computational, Cancer, RNA} biologist
VignuzziLab @VignuzziLab
16K Followers 9K Following viruses-evolution-Singapore-fitness! @idlabs_astar. #PrideInSTEM 🏳️🌈 #DiversityInSTEM 🇸🇬🇮🇹🇨🇦🇫🇷🇺🇸🇸🇦🇬🇧🇭🇺🇲🇾
QBI @QBI_UCSF
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Hiten Madhani MD PhD @hitenmadhani
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Bob Wachter @Bob_Wachter
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Joe Bondy-Denomy @joeBondyDenomy
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HOPE Collaboratory @HOPEforHIVCure
569 Followers 70 Following HOPE is an international collaboration of scientists and community working together towards a cure for HIV. Lead by @TheOttLab, @TheValenteLab and @ndhlovulab.
Stephen Floor @stephenfloor
10K Followers 1K Following Dad, partner, scientist, music lover. I am passionate about developing RNA technologies to impact human health. he/him snf @ bsky
Nature Biotechnology @NatureBiotech
302K Followers 2K Following Publishing the very best of biotech science and business. Part of @SpringerNature and @NaturePortfolio. On Facebook (natbiotechnol) & IG (nature.biotechnology)
Katelyn Luo @katelyn_luo13
2 Followers 4 Following
CZI Science @cziscience
27K Followers 573 Following Supporting the science and technology that will make it possible to cure, prevent, or manage all disease by the end of the century.
Buck Institute @BuckInstitute
16K Followers 1K Following Our mission is to end the threat of age-related disease for this and future generations
The Sato Lab (Kei Sat.. @SystemsVirology
20K Followers 2K Following 東京大学医科学研究所システムウイルス学分野教授 The Genotype to Phenotype Japan (G2P-Japan) Consortium主宰 一般社団法人G2P-Japan代表理事 週プレNEWSでコラム連載中→https://t.co/zLvSNcurTq
Rahul K Suryawanshi @rahulsurya85
24 Followers 62 Following
Roose Lab UCSF @roose_jeroen
720 Followers 287 Following Professor @UCSF, Dept. of Anatomy, studying cell fate decisions in disease. #ImmunoX, #UCSFCancer, #Immunology, #Organoids, #Signaling
Satchin Panda @SatchinPanda
53K Followers 87 Following Professor at Salk Institute. Author of the books, The Circadian Code and The Circadian Diabetes Code. https://t.co/GUiq4LWd4L
Ryan Flynn @raflynn5
5K Followers 620 Following RNA, Glycans, Space, Renewable Energy, and all technologies making lives more interesting. Now @BCHStemCell + @HSCRB. he/him
Wilson Poon @wilsonpoon
2K Followers 2K Following 🇨🇦👨🏻🔬 Asst Prof @UTEP ⛏️🏜️🤙🏻 MMBME #newPI @ThePoonLab || Interested in nano-bio interactions, drug & gene delivery || x-@bme_uoft 🍁 x-@UCSF 🌁
Jesse Chen @shineonjess
29 Followers 49 Following PhD student @VanderbiltU in the Skaar Lab👩🏻🔬 | @UCBerkeley alum | Mom to two cats 🐈 | 🇹🇼
Lorena Zuliani Alvare.. @LorenaZAlvarez
304 Followers 279 Following Principal Scientist @Novartis IOH. Interested in viruses, immunology and gene therapy 🧪🦠🧬
Carette Lab @CaretteLab
340 Followers 183 Following Studying host pathways that are critical for viral infection to reveal virus host relationships, illuminate basic cellular biology, and inform antiviral design
Ludivine Grzelak @LudivineGrzelak
151 Followers 201 Following Postdoctoral scholar in @TheOttLab,@GladstoneInst Previously PhD student in @Virus_Immunity lab @InstitutPasteur, Paris
Charmaine Soco @drcharmaine
166 Followers 384 Following Postdoc @StanfordMed @StanfordPeds contributor @ ISEHSociety @stanfordSURPAS Previously @Cityofhope #hematology #BMT #omics #stemcells
Bloom Lab @jbloom_lab
48K Followers 1K Following Lab studying molecular evolution of proteins and viruses. Affiliated with @fredhutch @HHMINEWS @uwgenome. @jbloomlab@bsky
Patricia Defechereux @PatriciaDefech1
18 Followers 28 Following Mum, poet, dancer, horse lover, spirit of the forest, HIV researcher with a passion for health equity and justice
Rachel Padget @rae_padget
667 Followers 362 Following Scientist | cardiovascular biology🫀 | avid outdoor lover | gamer | B.S. @UCentralMO M.S. @MissouriState Ph.D. @VT_TBMH
Keith (🦠,🦠) @keithvvvv
139 Followers 463 Following
Chiu laboratory at UC.. @Chiulab_UCSF
60 Followers 8 Following The Chiu Lab has made numerous discoveries in emerging viruses such as SARS-CoV-2 and use of metagenomic sequencing and host profiling to diagnose infections.
Fujimori Lab UCSF @FujimoriLabUCSF
2K Followers 704 Following https://t.co/oSwZKCG7Me Post-transcriptional and Post-translational regulation. #epigenetics #ribosome
Taha Y. Taha @ttaha801
280 Followers 2K Following Husband, father, virologist, pharmacist, soccer player, and chess enthusiast 🦠🧬😷 🥼 🔬⚽♞ Working on HBV and SARS-CoV-2 @TheOttLab @GladstoneInst
Lei Wang @WangUCSF
247 Followers 69 Following Professor @UCSF's Pharm Chem, CVRI, and @UCSFCancer Genetically encoding unnatural amino acids to study biological processes and to develop biotherapeutics.
Charles Chiu @cychiu98
3K Followers 78 Following
Curative @Curative
2K Followers 404 Following Empowering communities with innovative #healthcare solutions focused on affordability and transparency. Join us in revolutionizing the future of health care.
Lee Spraggon, PhD @lee_spraggon
594 Followers 457 Following Genomic Engineering-Functional Genomics-Disease Models-Diagnostics. Former @curative, @Synthego, @OXGENEofficial, @sloan_kettering
Fred Turner @FredTurnerBio
2K Followers 806 Following Curative CEO - building the next generation of employer health insurance with no copays and no deductibles removing barriers to care
Bharath Sreekumar @Bharath8891
59 Followers 98 Following
Abdullah Syed @abdullah_m_syed
287 Followers 273 Following NSERC postdoc @doudna_lab @GladstoneInst working on gene editing and SARS-CoV-2| PHD @TheChanLab
DARE Collaboratory fo.. @DAREtoCureHIV
1K Followers 188 Following A collaborative team of researchers and community representatives working to identify effective approaches to achieve an #HIVcure.
H-CRIS_Lab NMIMR @H_CRISLab_NMIMR
110 Followers 99 Following We are exploring HIV cure strategies by using novel compounds, medicinal plants or extracts that can reactivate, inhibibit and/or block and lock the virus
Black Microbiologists.. @BlackInMicro
10K Followers 163 Following Black Microbiologists Assoc Official Twitter Page #BlackInMicro Contact: [email protected] Get connected with us: https://t.co/qzn1Dm2CCI
BlackInImmuno @BlackInImmuno
6K Followers 681 Following A collective of scientists celebrating, amplifying, and promoting the work of Black #Immunologists across the globe.
TheValenteLab @TheValenteLab
177 Followers 77 Following Our laboratory focuses on the molecular interactions occurring within a host cell that are critical for HIV replication, particularly HIV transcription.
solspiré @solspire
221 Followers 390 Following Pauline Sameshima. Professor. Editor-in-chief of @JCACSRACEC. Curator of https://t.co/zm8nf6NdC1
MHRP @MHRPInfo
1K Followers 350 Following U.S. Military HIV Research Program (MHRP) at @WRAIR strives to end HIV. Views are HJF program staff and not official Army/DoD or HJF. engagement ≠ endorsement.
Ndhlovu Lab @ndhlovulab
290 Followers 178 Following Lish Ndhlovu's Lab @WeillCornell focuses on transformative precision research | to eradicate HIV | and advance healthy aging l Tweets by lab members
Tina Liu @tinaliu_phd
645 Followers 536 Following Assistant Prof of Molecular Bio & Biochem @RutgersCABM | Exploring & Engineering CRISPR-Cas systems | Former @doudna_lab postdoc | PhD @RapoportLab
Gavin Knott @gavinjknott
1K Followers 792 Following RNA Biochemist | Nucleic Acid Sensors | CRISPR | Lab Head @MonashBDI | Postdoc @doudna_lab | Ph.D. UWA. Views my own.
Innovative Genomics I.. @igisci
16K Followers 938 Following Using genome engineering to solve humanity’s greatest problems in health, climate & sustainable agriculture. Partnership between @UCBerkeley and @UCSF. #CRISPR
Savage Lab @SavageCatsOnly
2K Followers 478 Following Compartmentalizing your metabolism, and y’know, CRISPR stuff. Account managed by grad students and postdocs 🤙 @UCBerkeley @berkeleyMCB @igisci @HHMINEWS
Hayashi.Jen @hayashi_jen
42 Followers 77 Following Scientist, friend of dogs, and food lover. Alum of @UCDAVIS and @UMASS. Postdoc in the @OttLab. (she/her)
Jeffrey Shu (he/him) @jawfreyshoe
455 Followers 1K Following M3 @CleClinicLCM. Interested in ID🦠+ LGBTQ disparities 🏳️🌈 + precision medicine. 🧬. Previously @UU_University, @univgroningen, @UCBerkeley.
Stephanie Stephens @StephersonSays
17 Followers 67 Following
Synthego @Synthego
7K Followers 2K Following The Genome Engineering Platform Company. 🧬 #CRISPR #GenomeEngineer
Dr. Angela Rasmussen @angie_rasmussen
453K Followers 8K Following Virologist. PI @VIDOInterVac. Adj Prof @USask BMI. P2 @covarr_net. Jeopardy! loser. Famed for my obnoxious turns of phrase. 🇺🇸in🇨🇦. she/her
Mammoth Biosciences @mammothbiosci
6K Followers 2K Following Improving lives by reading and writing the code of life.
Sheila Chari @SheilaChari
1K Followers 299 Following feminist, scientist, daughter of immigrants, eats vegetables for breakfast, Editor in Chief @CellStemCell (opinions are my own) she/her.@TheOttLab is #hiring a Research Associate to contribute #bioengineering and molecular biology skills for ongoing #virology research. Learn more: bit.ly/3SqDxhc #ScienceJobs #ScienceCareers #Jobs
Looking forward to a peaceful night! Finally submitted my R25 as a PI for #PUMAS. An amazing program that I’m honored to lead, with Melanie Ott @TheOttLab PUMAS is an education internship program supporting URM students from community colleges! @GladstoneInst #internship #URM
Mir Khalid, scientist in the Ott Lab, describes how his passion for science started at a young age.
We partnered at the @BuckInstitute for Research on Aging with the team at @juvlabs to develop a premium ketone ester. Our team is thrilled about the new breakthrough taste! Cognitive Switch is now available on Amazon (see link below) a.co/d/4lw10rQ
HOPE has an incredible community team and Tom Villa has gone above and beyond for HIV research! Check out the @SauDiversidade podcast ‘HIV From Chaos To Cure’ on Spotify! #hiv #aids #hivcure #uequalsu #hivadvocate open.spotify.com/episode/4D2Yeg…
I am also a meme-lord! 😀😀
Our favorite lab jokester🤡, @mirmkhalid, was featured @GladstoneInst!👏👏 👨🔬Learn more about his unique hobbies and journey in science below! 👇 gladstone.org/news/meet-glad…
How do you know that the senior design project deadline is tomorrow? When all your students are in the lab cramming in one more experiment! 🥼🥽⚗️🧫🧪🔬😎
🚨 NEW🚨 "Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant" @TheOttLab @mirmkhalid @UCSF bit.ly/3ndi4a0
We designed and optimized pGLUE: a Golden Gate-based system to assemble viral genomes. We can reliably assemble infectious clones and replicons within 1 week. This enables mechanistic analysis of SARS-CoV-2 phenotypes and characterization of regionally emerging variants rapidly.
Using pGLUE, we generated naturally occurring Deltacron variants and demonstrated that BA.1 mutations in ORF1ab and Spike are responsible for the low replicative capacity of BA.1 in cell and animal models of infection.
We systematically investigated which mutation is responsible by generating mutant replicons where BA.1 mutations were reverted to Delta for each viral protein. We found that BA.1 NSP6 is responsible for almost all of the deficit in BA.1 viral RNA replication.
NSP6 plays a critical role in zippering ER membranes and channeling lipids towards replication complexes (nature.com/articles/s4158…).
We found that BA.1 NSP6 has reduced lipid droplet consumption compared to WT NSP6 and this likely plays a role in its observed attenuated RNA replication phenotype. We're currently conducting detailed follow up analysis on these observations.
This work would not have been possible without the help of many scientists in @TheOttLab and @doudna_lab, especially @irenechen_png and @hayashi_jen! Thank you!!! 🙏 Also huge shout out for rotation students @keithvvvv and @gabbykimmerly for significant contributions!
🥳🥳🥳🥳 Our paper systematically characterizing #SARSCoV2 Omicron BA.1 attenuation is now out in @NatureComms!!! rdcu.be/darQ9 A brief 🧵.
“You’ll never use this in the real world” they said
March 14 @stemcellreports. Learned a lot, analyzing human airway #organoids & #COVID. cell.com/stem-cell-repo…. THX @TheOttLab @alexis_combes @GabiFragiadakis @lisiena_lissi @sigallab @niaid @TheMarkFdn. Now back to tumor organoids & immune cells. Postdoc positions.
🗣️ BA1 Omicron variant transmissibility VS low death rate - Mélanie Ott
Who did I find in San Francisco today? My previous PI, PhD supervisor from @Virus_Immunity, giving a very nice presentation for the new partnership between @QBI_UCSF and @institutpasteur! Happy to see you here @OlivierSchwartz !
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