Vidhya Murthy @VidhyaMurthy1
Consultant Haematologist with an interest in myeloid malignancies. Birmingham, England Joined March 2020-
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Following304
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Vidhya Murthy retweeted
We report incidence of NPM1-wildtype relapses in pts treated with VEN-based frontline tx in AML. 🔴Overall, absolute # of relapses in NPM1 AML after VEN is ⬇️ 🔴the fraction of NPM1-wildtype relapses ⬆️ with the⬆️ intensity of chemo backbone added to VEN. 🔴 NPM1 wildtype…
We report incidence of NPM1-wildtype relapses in pts treated with VEN-based frontline tx in AML. 🔴Overall, absolute # of relapses in NPM1 AML after VEN is ⬇️ 🔴the fraction of NPM1-wildtype relapses ⬆️ with the⬆️ intensity of chemo backbone added to VEN. 🔴 NPM1 wildtype… https://t.co/TEq01o21k8
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Vidhya Murthy retweeted
Peripheral cell morphological alterations may signal early dysplastic shifts. In the Lifelines cohort, a high RDW links to high-risk mutational patterns in CH and stratifies the risk of death in CCUS buff.ly/Yt6TAKE @LifelinesNL @umcg
Vidhya Murthy retweeted
Outcomes of patients with newly diagnosed acute myeloid leukemia with FLT3-tyrosine kinase domain mutations: Prognostic implications of NPM1 co-mutation acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn…
Vidhya Murthy retweeted
1/4 SERUM FERRITIN Regulated at two levels: ✅ Cytokines (transcriptional control) ✅ Iron levels (translational control)
Vidhya Murthy retweeted
Vidhya Murthy retweeted
Vidhya Murthy retweeted
🔥 2025 ELN CML MANAGEMENT UPDATE 🔥 📌 Diagnosis 🧬 •Mandatory detection of BCR::ABL1 via CBA, FISH, RT-PCR. •NGS recommended in blast phase (BP), not routine in chronic phase. •ASXL1 mutations 🔬 → adverse prognostic marker in CP. •Transcript type (e13a2 vs e14a2) may…
Vidhya Murthy retweeted
Disease Trajectories and Glucocorticoid Exposure in VEXAS Syndrome Treated with Cytokine-Directed Therapies sciencedirect.com/science/articl…
Vidhya Murthy retweeted
Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndrome ashpublications.org/blood/article/… 10 year project with Irene Roberts and numerous collaborators. Natural history of myeloid preleukaemia and leukaemia in newborns and young children with T21.
Vidhya Murthy retweeted
It’s finally out in Blood!! A new molecular scoring system improving ESA response prediction in LR-MDS (ESA-PSS-M). Check it out! Thanks to all the collaborators #precisionmedicine #MDS ashpublications.org/blood/article-…
Vidhya Murthy retweeted
South India’s longest-know Car-T therapy survivors in Bengaluru return to daily life | Bengaluru News - this is amazing news @Immuneel_ is really delivering on its promise of curing incurable cancers. So proud to hear these heart warming stories. timesofindia.indiatimes.com/city/bengaluru…
Vidhya Murthy retweeted
#regenerative medicine in type 1 DM: #Stem cell–derived islets (zimislecel) infusion in portal vein restored islet function @NEJM Outcomes in 14 patients -All patients had detectable C-peptide -100% reached HbA1c <7% -83% became insulin-independent nejm.org/doi/full/10.10…
Vidhya Murthy retweeted
Intermediate-Dose Cytarabine as Postinduction AML Therapy | NEJM Evidence evidence.nejm.org/doi/full/10.10…
Vidhya Murthy retweeted
Prognostic factors for allogeneic haematopoietic cell transplantation outcomes in primary refractory AML (2013–2022): A retrospective study by the adult AML working group of the Japanese Society for Transplantation and Cellular Therapy @BrJHaem share.google/3OE1DQ6wCnsyBZ…
Disappointing. Subgroup analysis will be key.
Disappointing. Subgroup analysis will be key.
Happy 15th Birthday to Queen Elizabeth Hospital @uhbtrust. Fantastic celebrations with Special Kind, Connected and Bold awards. Great to hear aspirations and strategies from the specialties and poster displays of their achievements.
Vidhya Murthy retweeted
CONGRESS | #EHA2025 | PRESENTATION Jianxiang Wang, Peking Union Medical College, shares results from a long-term follow up of the phase III COMMODORE trial (NCT03182244), of gilteritinib (n = 137) vs salvage chemotherapy (n = 139) in predominantly Asian patients with R/R FLT3m…
Vidhya Murthy retweeted
Vidhya Murthy retweeted
#EHA2025 #youngEHA Great presentation by Dr. DiNardo, how to improve on VEN+HMA for intensive ineligible AML pts.. 1. Ven resistance mechanisms. 2. Novel targets 3. Ven triplets under development #leusm #AML #venetoclax_4_AML
Vidhya Murthy retweeted
Lets start on updates and highlights from #EHA2025 with novel therapies for R/R #AML in development 👇🏽 presented by Norbert Vey #youngEHA #hemasphere #menin_inhibitors
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