Volynski Lab @VolynskiLab_UCL
Our lab is interested in synaptic transmission and cellular mechanisms of neurological disorders. ucl.ac.uk/ion/research/s… UCL QS Institute of Neurology Joined February 2020-
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Check this out. Our collaborative paper with Shyam Krishnakumar’s lab at Yale is now published (nature.com/articles/s4146…). Using a single vesicle fusion assay, we identify minimal protein machinery sufficient to account for various modes of calcium-triggered vesicle fusion.
Our collaborative manuscript with Shyam Krishnakumar’s lab at Yale just posted on bioRxiv (biorxiv.org/content/10.110…). Using a single vesicle fusion assay, we identify minimal protein machinery mediating synchronous and asynchronous SV exocytosis and short-term synaptic plasticity.
Exciting News! Our paper on computational modelling of evoked vesicular release has now been published. Explore how our model bridges molecular biochemistry with physiology, advancing our understanding of calcium-activated neurotransmitter release: nature.com/articles/s4200….
We're recruiting a Senior Molecular Biologist for the Molecular and Cellular Biology team at the Mary Lyon Centre, MRC Harwell. #CRISPR, #PCR, #nanopore sequencing, gene expression studies, and more. mrc.tal.net/vx/appcentre-e… Please RT!
Novel Roles for Diacylglycerol in Synaptic Vesicle Priming and Release Revealed by Complete Reconstitution of Core Protein Machinery biorxiv.org/content/10.110…
In memory of our dear colleague and friend Marco Capogna, professor of Neurobiology and DANDRITE affiliated researcher. His contribution to the neuroscience community has been numerous and very important. He will always stay in our thoughts and research dandrite.au.dk/display/artike…
📢 Very happy to share our paper just published in @ScienceMagazine in collaboration with @Newrotrash and led by the fabulous @sophieqyc_q! Activity-dependent Gene Therapy for Neurological Diseases #epilepsy #genetherapy @UCLIoN @EpilepsyRUK @The_MRC science.org/doi/10.1126/sc…
Just published in @natBME: expansion revealing (ExR), a 20x #expansionmicroscopy method that evenly separates proteins from each other for better antibody labeling, and nanoprecise imaging, on ordinary microscopes. Link to PDF: rdcu.be/cUyAO
Novel graphene arrays aid epilepsy research: Rathore & colleagues @LabWykes @VolynskiLab_UCL combine wide-field imaging with simultaneous ephys recordings using gSGFET arrays to study epileptic seizures in #awakemice. Add to your #FENS2022 to-do list, poster S04-144
And here it is -- communication from @ERC_Research to UK-based #ERC starting grant grantees... UK awardees will have two months time to move their grant to the EU proper, otherwise they will lose their STG. Thank you #Brexit #BrexitReality.
Introducing #panExM-t: a protocol where 🧠 tissue is expanded ✨24x✨, pan-stained with NHS ester, and immunolabeled. Now you can see everything in the brain, even synaptic densities 👇. High potential for #connectomics! bioRxiv: biorxiv.org/content/10.110…
Thrilled to see this work finally out in @SfNJournals #JNeurosci – study led by @VicGSB and @markrigbu. Beautiful work characterising GEVIs for measuring AP waveform in neurons and imaging APs along axons. See thread by @markrigbu for more info. @dev_neuro @MRC_CNDD @KingsIoPPN
Thrilled to see this work finally out in @SfNJournals #JNeurosci – study led by @VicGSB and @markrigbu. Beautiful work characterising GEVIs for measuring AP waveform in neurons and imaging APs along axons. See thread by @markrigbu for more info. @dev_neuro @MRC_CNDD @KingsIoPPN
Epilepsy gene therapy - 3 postdoc positions with @LignaniLab_UCL Stephanie Schorge, Matthew Walker and me. Spread the word! #1: bit.ly/3yL5C72 #2: bit.ly/3fut1Sz #3: bit.ly/3i52tJ9
Calcium dependence of neurotransmitter release at a high fidelity synapse biorxiv.org/cgi/content/sh… #bioRxiv
We are hiring! @NeuroNaud and I are looking for a Ph.D. student and a postdoc to explore how neurons integrate synaptic signals and networks code information in the hippocampus during memory formation. Join our collaborative team!
Check our new paper just out today! rdcu.be/ckCmM
Check this out. Our new manuscript just posted on bioRxiv biorxiv.org/content/10.110…. Using SF-iGLuSnFR, we image quantal glutamate release with ~75 nm spatial and 4 ms temporal resolution and find a universal relationship between probability and synchronicity of vesicular release.

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UCL Queen Square Inst... @UCLIoN
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