Jack Dent @_jackdent
Co-Founder @ Chai Discovery Joined May 2011-
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Thank you @Nasdaq for the kind words and for lighting up Times Square! 💙 Excited to keep pushing the boundaries of molecular design with AI.
@chaidiscovery is transforming biology from science into engineering. Congrats to @joshim5, @_jackdent, and the team on today’s Series A announcement! It’s been incredible to see Chai's amazing breakthroughs and execution in such a short amount of time.
@chaidiscovery is transforming biology from science into engineering. Congrats to @joshim5, @_jackdent, and the team on today’s Series A announcement! It’s been incredible to see Chai's amazing breakthroughs and execution in such a short amount of time.
Chai marches on towards one shot AI drug design
Chai marches on towards one shot AI drug design
Nudge is working on one of the most important problems in our lifetime. What an incredible endorsement of their world-class team and rate of progress.
Nudge is working on one of the most important problems in our lifetime. What an incredible endorsement of their world-class team and rate of progress.
NewLimit paper just dropped @icmlconf showing our SOTA AI models can predict perturbed cell states. Helps to have the largest primary cell perturbation dataset in the world. Bonus points for one of the first demonstration of active learning in bio.
Some use cases are cooler than others, and it's safe to say zero-shot antibody design is one of them. Congrats on launching Chai-2!🧬
Some use cases are cooler than others, and it's safe to say zero-shot antibody design is one of them. Congrats on launching Chai-2!🧬
Big thank you to stellar engineering team at @modal_labs, who provided some critical infrastructure for this effort. They are a joy to work with.
Big thank you to stellar engineering team at @modal_labs, who provided some critical infrastructure for this effort. They are a joy to work with.
Chai Discovery (@joshim5 @chaidiscovery) just released Chai-2, a model for "zero-shot antibody design in a 24-well plate." The most existing result? Chai-2 successfully generated binders for 50% of the 52 targets they assayed (100x better than SOTA)! Some thoughts below:
We’re excited to introduce Chai-2, a major breakthrough in molecular design. Chai-2 enables zero-shot antibody discovery in a 24-well plate, exceeding previous SOTA by >100x. Thread👇
Introducing Warp 2.0: the Agentic Development Environment 1️⃣ Top overall coding agent: #1 on Terminal-Bench, 71% on SWE-bench Verified 2️⃣ Agent multi-threading: build features, debug, and ship all at once 3️⃣ The first all-in-one platform for agentic development 🧵 Learn more
We're excited to partner with the UK Government on OpenBind, an effort to create the largest open dataset of drug-protein interactions in history. More data → smarter AI models → better medicines gov.uk/government/new…
We’ve raised a $130 million Series B led by @kleinerperkins alongside new investors @natfriedman/@danielgross , @vkhosla, and @humancapital — joined by existing investors @foundersfund , @_DimensionCap, and @brian_armstrong (yes, the cofounders are doubling down). We also raised…
We got a robot to clean up homes that were never seen in its training data! Our new model, π-0.5, aims to tackle open-world generalization. We took our robot into homes that were not in the training data and asked it to clean kitchens and bedrooms. More below⤵️
Excited to share details of what we are working on @nudge for the first time today. Our mission is to improve everyday life by developing the best technologies for interfacing with the brain.
Excited to share details of what we are working on @nudge for the first time today. Our mission is to improve everyday life by developing the best technologies for interfacing with the brain.
Life update - I have joined Chai Discovery as part of the founding team earlier this year! A rather belated announcement, but I want to take the time to thank all friends, share some reflections, and talk more about things ahead that excite me most. Post: substacktools.com/sharex/EYdWWDAZ
Introducing Warp on Windows – the intelligent terminal built for speed, AI, and collaboration. Download today – more on what’s in the box 🧵 warp.dev/windows-termin…
Excited to announce the general availability of Chai-1 in SAMSON! Like AlphaFold 3, Chai-1 is a state-of-the-art foundation model for biomolecular structure prediction which handles proteins, small molecules, DNA, RNA, glycosylations, etc. One particularly exciting feature is the…
Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @MSFTResearch AI for Science. #ML #AI #NeuralNetworks #Biology #AI4Science biorxiv.org/content/10.110…

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