Selami Demirci @demircislm
Staff Scientist @NIH | Genome editing, CRISPR, Stem Cells, Regenerative medicine & Reprogramming scholar.google.com.tr/citations?user… Joined December 2013-
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Selami Demirci retweeted
Check out this gene-editing approach to treat serious blood diseases using rhesus macaques conditioned with a CD45 antibody-drug conjugate. By @NIH_nhlbi J. F. Tisdale, @demircislm @NIH & @harvardstemcell D. E. Bauer in @CellStemCell #ASGCT2025 hubs.li/Q03mxk_d0
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Selami Demirci retweeted
Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in @Nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. nature.com/articles/s4158…
There were so many great stories and exciting updates on prime editing, base editing, CART cells, in vivo delivery, virus-mediated therapies, and many more in this year’s ASGCT meeting. Can’t wait for next year’s meeting in Baltimore. #ASGCT2023 #Science
Delighted to have our paper, which shows efficient and long-term engraftment of CRISPR-Cas9 edited rhesus hematopoietic stem cells despite pre-existing Cas9 immunity, out in Molecular Therapy—Methods & Clinical Development. cell.com/molecular-ther… @MolTherapy @ASGCTherapy :
Selami Demirci retweeted
Rebuilding earthquake damages/trauma in Turkey would require tens of billions of dollars and years. Please consider helping through your trusted organization. Or you can use @ahbap, the most prominent volunteers organization besides the Turkish government. ahbap.org/disasters-turk…
Selami Demirci retweeted
CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering go.nature.com/35UxTLY
Selami Demirci retweeted
BCL11A enhancer–edited hematopoietic stem cells persist in rhesus monkeys without toxicity: buff.ly/32AJXju @demircislm @nih_nhlbi @NIDDKgov #Hematology #Transplantation
Selami Demirci retweeted
Genetic strategies aimed correcting a defective β-globin gene or inducing fetal globin for patients with beta-hemoglobinopathies offer a potential solution for disease- and treatment-free survival. @demircislm @AlexisLeonardMD @NIH_NHLBI doi.org/10.1093/hmg/dd…
Selami Demirci retweeted
Biallelic correction of sickle cell disease‐derived induced pluripotent stem cells (iPSCs) confirmed at the protein level through serum‐free iPS‐sac/erythroid differentiation #genomeediting #hematopoiesis #hESCs #iPSCs #serumfree #sicklecell bit.ly/32YAy6f
Interactive plots with R programming are so fun. @bioinfoacademy
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