Dominic Yap @dominicyap_
Joined November 2013-
Tweets18
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Followers57
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Following181
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In meta-analysis, moderate-certainty that 47% of wet AMD pts had retinal fluid after 2y of anti-VEGF treatment. Cure-models predict that up to 18% of patients may never achieve fluid resolution @dominicyap_ @BenjaminKJTan @snec_seri @NUSMedicine @mysgh ow.ly/cCFo50USqRb
Finally, a honest, plausible academia-driven and patient-centred analysis on IO biomarkers without secondary, for-profit agendas. Great job Dr Leone 🦁 & collaborators across the globe. A 🇸🇬🇮🇹 joint effort. @FilippoPietran4 @JAMAOnc
Finally, a honest, plausible academia-driven and patient-centred analysis on IO biomarkers without secondary, for-profit agendas. Great job Dr Leone 🦁 & collaborators across the globe. A 🇸🇬🇮🇹 joint effort. @FilippoPietran4 @JAMAOnc
How do we understand 2 independent meta-analyses published the same week (Yap et al JAMA Onc 2022 N= 4752; Wu et al JCO 2022 N=2908) evaluating the same question but coming to opposite conclusions?? jamanetwork.com/journals/jamao… pubmed.ncbi.nlm.nih.gov/36473145/
How do we understand 2 independent meta-analyses published the same week (Yap et al JAMA Onc 2022 N= 4752; Wu et al JCO 2022 N=2908) evaluating the same question but coming to opposite conclusions?? jamanetwork.com/journals/jamao… pubmed.ncbi.nlm.nih.gov/36473145/
The controversy continues. We just published in @JAMAOnc an analysis showing minimum benefit of immunotherapy for low PD-L1 expressing esophageal tumors jamanetwork.com/journals/jamao…, @FengWan25720657 shows the opposite ascopubs.org/doi/10.1200/JC…. are we none the wiser? @FilippoPietran4
Efficacy of ICI in ESCC patients with low PDL1 expression: Our pooled analysis shows there may not be OS benefit in TPS<1% pts. Harmonised biomarkers needed for better pt selection @FilippoPietran4 @sundar__raghav @NickyWongZH @josephjzhao ja.ma/3UIM5xB @JAMAOnc
CheckMate-649: 🚫 No survival benefit from nivolumab + chemotherapy in CPS 1-4 gastroesophageal adenocarcinoma ➡️ fal.cn/3kBHk #JCO #esocsm #stcsm @josephjzhao
Analysis of data from CheckMate 649, KEYNOTE-062 and KEYNOTE-590 suggest that pts with PD-L1-low advanced-stage gastric/GEJ adenocarcinoma might derived no benefit from the addition anti-PD-1 antibodies to first-line chemotherapy: ascopubs.org/doi/full/10.12… #stcsm #esocsm
Very well done Dr. Joseph J. Zhao & colleagues on conducting this study. All of us have been looking for these KM curves. @JCO_ASCO #JCO #patients with ⬇️ PD-L1 expression è #Gastric #Esophageal #cancers didn’t benefit from ICIs @OncoAlert ascopubs.org/doi/abs/10.120…
@LizzySmyth1 @OncoAlert @JCO_ASCO @sundar__raghav @VJOncology @myESMO No doubt pts with low CPS has less benefit. Hopefully ongoing studies LEAP-015, Attraction-6, chemo+RegoNivo or other agents (zolbetuximab and bemarituzumab) will improve outcomes of these patients
This is innovative and important work in @JCO_ASCO from @sundar__raghav Computational analysis can accurately derive unpublished subgroup results in clinical trials 🤯🤯 ! This approach has the potential to be a game changer! Well done 👏👏 @OncoAlert @VJOncology @myESMO
This is innovative and important work in @JCO_ASCO from @sundar__raghav Computational analysis can accurately derive unpublished subgroup results in clinical trials 🤯🤯 ! This approach has the potential to be a game changer! Well done 👏👏 @OncoAlert @VJOncology @myESMO
Thanks to my friend @sundar__raghav for this extremely important work. For HER2- #gastric #cancer, immunotherapy is not effective, not only in CPS 0 subgroup, but also in CPS 1-4 and 1-9. For these subgroups, immune-sensitizing strategies are needed!! ascopubs.org/doi/full/10.12…
Pleased to present data that most GI oncologists have been asking for, but not gotten so far: role of Nivolumab in CPS 1-4 gastric cancer. ascopubs.org/doi/full/10.12… Answer: Minimum to none. EMA has restricted approval to only CPS >= 5. What about FDA?
In this meta-analysis of 4,885,518 patients from four observational studies, patients with OSA had approximately 30% higher risk of lung cancer, compared to those without OSA. @yaohao_teo @yaoneng_teo @dominicyap_ atsjournals.org/doi/10.1513/An… @AnnalsATS
OptionFlow_TA🇺🇸 @Qarlet5389578
26 Followers 2K Following 15-30% Monthly | 2 High-Conviction Stocks.Short-Term Gains: 15-20% in Days/Weeks.DM "JOIN" for WhatsApp Alerts. Live Trade Signals • Market Analysis
Brian Yeo @brianyeosy
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Keng Siang Lee @kengsianglee
932 Followers 647 Following space occupying academic junior doctor | @KingsCollegeNHS Clinical Neuroscience #SFP | Co-PI for the SINO study with @Sjp58Price | 🇸🇬🇬🇧 |
Catherine @s_catherine10
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Chun En Yau @ChunEnYau
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Christopher Low @Chrislowjw
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NUS Medical Society @nusmedsoc
49 Followers 146 Following Official account of NUS Medical Society Yong Loo Lin School of Medicine @nusmedicine 🩺 Not Pride of Knowledge, But Humiliity of Wisdom
Ryan Ruiyang Ling @ryanryling
117 Followers 135 Following Editorial Board Member @crit_care | Affiliate Researcher @anzicrc | Medical Officer @anaesthesiaNUHS | Dean's Fellow @NUSMedicine | #anaesthesia #critcare #ECMO
Daniel Catenacci @DocCatenacci
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Natalie Ngoi @NatalieNgoi
126 Followers 100 Following Med Oncologist passionate about Gyn Cancers and Early Phase Trials |NCIS SG, GCGS, APGOT |ESMO Translational Research Fellow at IGR
Ryan Lee @AinsleyRyanLee
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Khi Yung @fongkhiyung
116 Followers 207 Following Department of Surgery, Singapore General Hospital // Yong Loo Lin School of Medicine, National University of Singapore MBBS MRCSI
Shaun Loong @loong_shaun
115 Followers 253 Following First-year physician | Cardiovascular researcher @ Foolab @ NUS | Research interests in cardiovascular omics
Medical Humanities Co... @medhums_sg
87 Followers 194 Following We hope to introduce medical students to the humanities, and to develop an appreciation for the world in medicine | Singapore 🇸🇬
Jared Ng @Jaredng_med
86 Followers 219 Following PGY1 Doctor @NUSMedicine '23 and @NUSCollege | Interests in #familymedicine Public Health, and Medical Humanities | @medhums_sg
John Z @john070617
39 Followers 168 Following Journal editors @liver disease (JCTH); @pathology (JCTP); medical research (ERHM); cancers (CSP); traditional medicine (FIM), etc.
Sunny @Sunny32260312
14 Followers 431 Following
Alex Cheong @alexjycheong
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Teo Yao Neng @yaoneng_teo
51 Followers 100 Following
Benjamin Tan @DrBenjaminTan
568 Followers 400 Following 🇸🇬Neurologist @NUHSofficial | Asst Prof @NUSMedicine | Visiting Fellow @CGM_MGH @BroadInstitute | #YoungStroke #StrokeGenetics 🧠🫀#HeartBrain @StroCarCollab
Nicholas Syn @Nicholas_Syn
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Nicholas Chew @Nicholaswschew
869 Followers 2K Following Cardiologist at #NUHCS, Singapore. Research interest in cardiometabolic + coronary + valve disease. Collaborations on Heart-Liver-Endocrine axis. Views my own.
Filippo Pietrantonio @FilippoPietran4
1K Followers 819 Following Medical Oncologist focused on #GI cancers. LOVE cats, trips, culture & RED wine.. the good one! 🏳️🌈@IstTumori @FoundationGONO
Toon Wei Lim 林顿�... @ToonWeiLim
587 Followers 516 Following Cardiologist, researcher, who loves good music, well-engineered cars and tasty coffee. Past President, Singapore Cardiac Society. @NUHS @NUSingapore
Sundar Sankaran @sundar_s1955
9K Followers 7K Following MD DNB FRCP FISOT Program Director Aster Institute of Renal Transplantation Bangalore Ex Adj Professor MAHE Ex Chairman ISN SC RTs not endorsements
Lizzy Smyth @LizzySmyth1
4K Followers 2K Following Medical Oncologist. Cancer Clinical Trials @OxfordCancer #GIcancer #ESMO #EORTC
Lin Weiqin @weiqin_lin
531 Followers 791 Following Clinical Director of HF & CMP Programme @ National University Heart Centre, Singapore (@NUHCS). Heart Failure | MCS | Cardiomyopathies. Opinions are my own
Wen Hui Lim @WenHuiLim4
102 Followers 229 Following Hello :) Wen Hui from @NUSmedicine here. Interested in liver transplant and excited to hang out with my dorky #GITwitter pals!
Darren Tan @DarrenTanJH
93 Followers 133 Following @NUSMedicine || Interested in all things liver-related, especially liver transplantation and malignancies || Views are my own
Cheng Han Ng @ChengHanNg
1K Followers 1K Following Physician, Biotech & Researcher of Metabolic Diseases | RT =/ Support
Ching-Hui SIA @chinghuisia
731 Followers 738 Following Advocate for heart & brain health!🫀🧠 NeuroCardiology @StroCarCollab. Multimodality Cardiologist-Scientist MBBS EMBA FESC @NUHCS & @NUSMedicine 🇸🇬
Qize Yang @yang_qz
0 Followers 4 Following
Jack Welch @jackdwelch
161 Followers 4K Following
Yang Chun Wei @probean123
8 Followers 33 Following Principal Bassoonist, Pianist, Programmer and App Developer HCI Bandits 2013-2016 | SC 2015-2016
z @ZSJshijie
0 Followers 78 Following
Jerald Kiew @JeraldKiew
9 Followers 114 Following
Bryan Yan @bryanyankj
50 Followers 86 Following
tamtam lee @BurceChristine
2 Followers 8 Following
The Metals Company @themetalsco
15K Followers 377 Following Building a carefully managed metal commons that will be used, recovered, and reused again and again. (NASDAQ: $TMC)
Nicole Piastri @NicolePiastri
152K Followers 63 Following
Dr Amol Akhade @SuyogCancer
8K Followers 138 Following Oncology care , to give or not to give chemo , data analysis , oncology pharamocovigilance , enthusiastic critic, twitts are not twists
Marios Georgakis @MariosGeorgakis
4K Followers 1K Following Physician-scientist leading a lab @LMU_Muenchen, visiting scientist @broadinstitute | Writing about genetics, omics, deep phenotyping
Brian Yeo @brianyeosy
12 Followers 10 Following
Zhiding Yu @ZhidingYu
8K Followers 555 Following Working to make machines understand the world like human beings. Words are my own.
Zizheng Pan @zizhpan
60K Followers 855 Following Researcher @deepseek_ai | Previously @nvidia @MonashUni @UniofAdelaide. Words are my own.
Evelyn Wong @EvelynWongYT
359 Followers 349 Following Medical Oncologist | Colorectal Cancer, GI Oncology | NCCS, @nccsingapore | young GI cancer | health economics | global health | Proud Mama ; Opinions my own
David R. Liu @davidrliu
74K Followers 64 Following Professor at Harvard, Broad Institute, & HHMI. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1
Google DeepMind @GoogleDeepMind
1.2M Followers 279 Following We’re a team of scientists, engineers, ethicists and more, committed to solving intelligence, to advance science and benefit humanity.
Demis Hassabis @demishassabis
488K Followers 146 Following Nobel Laureate. Co-Founder & CEO @GoogleDeepMind - working on AGI. Solving disease @IsomorphicLabs. Trying to understand the fundamental nature of reality.
Erik Massenzio @ErikMassenzio
309 Followers 243 Following @MidAtl_Retina Fellow '27 // @Wills_Eye '25 // @JeffersonUniv '21 // @Princeton '17
Eric Topol @EricTopol
678K Followers 605 Following physician-scientist, author of SUPER AGERS https://t.co/ZEdooyyJpP and Ground Truths: https://t.co/YhatcBT0hA
Cell @CellCellPress
262K Followers 603 Following Cell aims to publish the most exciting and provocative research in biology. Posts by Scientific Editors on the Cell Editorial team.
Cell Reports @CellReports
141K Followers 144 Following Cell Reports is an open-access journal at Cell Press, publishing weekly. Tweets by Cell Reports editors.
nature @Nature
2.6M Followers 3K Following Research, News, and Commentary from Nature, the international science journal For daily science news, get Nature Briefing: https://t.co/wGmQlQ8a4D
Nature Medicine @NatureMedicine
351K Followers 253 Following Nature Medicine is a research journal devoted to publishing the latest advances in translational and clinical research for scientists and physicians.
Michael T. Lawton, MD @mtlawton
19K Followers 514 Following Neurosurgeon. Innovator. Author. Teacher. President & CEO @BarrowNeuro. Spetzler Chair of Neurosurgery. Co-Founder @MissionBrainOrg.
Keng Siang Lee @kengsianglee
932 Followers 647 Following space occupying academic junior doctor | @KingsCollegeNHS Clinical Neuroscience #SFP | Co-PI for the SINO study with @Sjp58Price | 🇸🇬🇬🇧 |
Oren Gottfried, MD @OGdukeneurosurg
240K Followers 353 Following I work as a Duke Univ. Neurosurgeon/ Professor & TV Advisor, Producer, Writer, Actor. I post only from the med literature, Never my own or employer’s cases.
Tim Cook @tim_cook
14.9M Followers 70 Following Apple CEO Auburn 🏀 🏈 Duke 🏀 National Parks 🏞️ “Life's most persistent and urgent question is, 'What are you doing for others?'” - MLK. he/him
Vinay Prasad MD MPH @VPrasadMDMPH
313K Followers 4K Following These posts were issued before my FDA employment and do not necessarily represent the views of the FDA or the United States. The account is now inactive.
Ed Livingston @ehlJAMA
11K Followers 8K Following Deputy Editor for Clinical Reviews and Education @JAMA_Current Host JAMA Clinical Reviews from 2012-2021. Professor of Surgery, UCLA
Myriam Chalabi @MyriamChalabi
7K Followers 503 Following Medical Oncologist, GI cancers @nki_nl neoadjuvant #immunotherapy #cancerresearch. Opinions my own
David Phillippo @dmphillippo
394 Followers 273 Following @dmphillippo.bsky.social Statistician at University of Bristol | Bayesian, meta-analysis and evidence synthesis, #rstats | Musician and drinker of coffee
Sravan Panuganti, DO,... @SPuro88
9K Followers 1K Following Dad. Husband. Urology, BPH, Sex Med. Asst. Prof. @vcomcarolinas. Fel @UTHUrology/@MDAndersonNews. Res @JeffNJurology. DO @PCOMeducation. But first @PittTweet
Adam Cifu @adamcifu
26K Followers 813 Following Internist, professor, patient. Author: Ending Medical Reversal; Symptom to Diagnosis; Sensible Medicine. Podcasts: S2D & Clinical Excellence. Loves Baseball.
Todd Scarbrough @toddscarbrough
3K Followers 2K Following Sixty percent of the time, the things I try work every time. Radiation oncologist. Thaumaturgist. Todd Scarbrough is an anagram for 'doc brought rads.'
Medical Axioms @medicalaxioms
66K Followers 5K Following I’m Mark Reid, MD. I made @MedicalAxioms. My new book Individual Daily Risk will change the way doctors & scientists interpret RCTs: https://t.co/aYt5XDyhUL.
Bob Wachter @Bob_Wachter
242K Followers 289 Following Chair, UCSF Dept of Medicine. Career: What happens when a poli sci major becomes an academic physician. Author: "A Giant Leap" (2026). Hubby/Dad/Grandpa/Golfer.
Cllr Sam S Collins @NorthHertsSam
45K Followers 3K Following Hitchin Lib Dem Cllr - mostly talking or writing about small bits of racing cars/Engineering/interesting things like that. Hitchin Town FC fan.
Black Hole @konstructivizm
764K Followers 41K Following Only New Content, news, articles, images, videos, and discussion #space,#FollowMe, #Nature, #astronomy, #Nasa, #astrophotography, #science
Mark Evans @MEvansCambridge
1K Followers 459 Following Academic, clinician working in type 1 diabetes..World’s worst carb counter
Bryan Carmody @jbcarmody
54K Followers 887 Following The Sheriff of Sodium | Pediatric nephrologist | Associate professor | APD | Husband | Dad | Virginian | Advocate for medical students and common sense
Google for Health @GoogleForHealth
31K Followers 76 Following Official Google for Health news and updates on how we’re progressing our mission to help billions of people be healthier.
Dudes Posting Their W... @DudespostingWs
2.7M Followers 34 Following Ironically Funny and Wholesome. DMs open for submissions 🥂 DM for Removal or Credit
Dr. Nina Niu Sanford @NiuSanford
9K Followers 2K Following GI Radiation Oncologist | Boston, @Princeton, @harvardmed, now @UTSWNews in Dallas | clinical trials | buying in bulk | Tweets=own | FCOI: https://t.co/EjwMnJKbth
Shengwu Li @ShengwuLi
37K Followers 721 Following Economist. @Harvard. Mechanism design, behavioral theory.
TOYOTA GAZOO Racing @TOYOTA_GR
748K Followers 462 Following トヨタ自動車のTOYOTA GAZOO Racing公式Xアカウントです。GRの最新車種情報や国内外のモータースポーツの最新情報をお届けしています。
Larry the Cat @Number10cat
870K Followers 146 Following Chief Mouser to the Cabinet Office. 18 year old tabby. Living with my sixth Prime Minister. Unofficial. I am the media, miaow.
Regeneron @Regeneron
33K Followers 285 Following Official channel for Regeneron. We turn science into medicine for people with serious diseases. View our terms of engagement here: https://t.co/EuFDUdQQ5E
Pfizer Inc. @pfizer
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AstraZeneca @AstraZeneca
295K Followers 2K Following We're transforming the future of healthcare by unlocking the power of what science can do. Community Guidelines: https://t.co/Kh08zUdFpT
Novartis @Novartis
292K Followers 518 Following An innovative medicines company working to reimagine medicine. See our community guidelines: https://t.co/wolzG1zLye
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