Annabel Short @drbelshort
Joined August 2016-
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Ever wondered why chronic steroid use can cause #dementia? Excited to share our paper with @staffordlightma @BeckyConwayCam2 @BristolUni out today in @PNASNews ! Check it out below⬇️ pnas.org/doi/10.1073/pn…
In case you missed it, check out our @z_baram lab's latest work in @NatureComms . We identified a #stress-sensitive projection from BLA-NAc, and found inhibiting it AFTER early life adversity rescued reward behavior! Find the @NIMHgov funded study here: nature.com/articles/s4146…
Inspired by thoughtful discussions, happy to share our paper with @kbath77 @meghan_gallo and collaborators @drbelshort @z_baram exploring the impact of resource scarcity and maternal separation in mice on maternal signals and pup amygdala gene expression doi.org/10.1016/j.ynst…
Congrats Rachael 🥂🎉
Thrilled to share @ScienceMagazine piece, a 10 yr obsession: developing brains get signals from the environment that shape emotional circuit maturation & impact mental health. What signals? which ones are 'bad'? how do they influence circuit refinement? science.org/doi/10.1126/sc…
YAYYY, my big paper from my postdoc on #microglial pruning of stress-sensitive CRH+ neurons during early-life stress is finally out!!! This has been >5 years in the works, so big shout out to all co-authors, and especially my mentor @z_baram (thread below) cell.com/cell-reports/f…
Postdoc work with @z_baram @calizavi @JessicaLBolton @mtbirnie is in press!🎉 doi.org/10.1016/j.bpsg… Check out our work using single cell transcriptomics of stress-sensitive CRH neurons to identify populations impacted by early-life adversity in open access @BiologicalPsyc1
Early-Life Adversity Blunts Reward Responsiveness in Adulthood rdcu.be/cFvEj @DiegoPizzagalli @npp_journal
Come join us for a Postdoc in California! employ #singlecell transcriptomics #merFISH and functional approaches to early-life #stress effects on #reward #amygdala #PVT. sciencedirect.com/science/articl… frontiersin.org/articles/10.33… Current folks are getting own labs! @FENSorg @LisaMonteggia
Excited to share! combined data & biology-driven approaches to single cell transcriptomics of #stress-sensitive #CRH neurons identifies novel cell populations & shows selective impact of earlylife adversity. Kudos @drbelshort @calizavi @BiologicalPsyc1 sciencedirect.com/science/articl….
Thrilled to share the power of common measures in humans and experimental animals to test mechanistic hypotheses on the impact of #early life #stress on #reward sensitivity. Now out in @npp_journal @ACNPorg great collab with @DiegoPizzagalli @drbelshort nature.com/articles/s4138…
Interested in early-life #stress? in humans? The QUIC, a user-friendly instrument for studying parental & environmental unpredictability-a novel important actionable early adversity- is on line. In English and Spanish! Dutch, German & Finnish versions soon contecenter.uci.edu/questionnaire-…
Cool @drbelshort & @calizavi single-cell transcriptomics work on #stress-regulating CRH cells in developing hypothalamus. Combined data-and neuroscience-driven clustering identifies novel populations, which are specifically targeted by early-life stress. biorxiv.org/content/10.110…
Dear Twittexperts: how do you define a neuron (in hypothalamus) as glutamatergic? do you have a non vGlut2mRNA method you can share? TX! (see unhelpful example of vGlut2 IHC).@superkash @StephenMaren @svmahler @AllenInstitute @MarinaP63 @Herman_lab @Bangasser_Lab @TrendsNeuro
SO proud @JessicaLBolton! >4 yrs of passion & smarts. 4-D live imaging of microglia-neuron interaction in neonatal mice in situ! Chronic chemogenetic microglia activation in neonates sans injection stress! yes. microglia mediate ELS effect on circuit maturation
SO proud @JessicaLBolton! >4 yrs of passion & smarts. 4-D live imaging of microglia-neuron interaction in neonatal mice in situ! Chronic chemogenetic microglia activation in neonates sans injection stress! yes. microglia mediate ELS effect on circuit maturation https://t.co/X5jvwkCtaX
Excited to finally share my scientific "baby", the result of my K99 work with @z_baram, @LaboTremblay, @drbelshort and many others, now under review and posted for your enjoyment on @biorxiv_neursci doi: doi.org/10.1101/2021.0…. Read on for the summary blurbs...#microglia #CRF
Dont miss! Tomorrow: Conte Center@UCI symposium 9AM PDT. Exciting talk with Kerry Ressler; poster tours; datablitz; hot-off-the press COVID research. Join ~300 participants-open to all. sign up today contecenter.uci.edu/symposia/
Our @SfNJournals #JNeurosci paper is officially published! jneurosci.org/content/41/4/6… Here we investigate the role of #EstrousCycle #estrogen on the effects of acute #stress on #memory . See my prior thread for details! @z_baram @drbelshort @JessicaLBolton
Our @SfNJournals #JNeurosci paper is officially published! jneurosci.org/content/41/4/6… Here we investigate the role of #EstrousCycle #estrogen on the effects of acute #stress on #memory . See my prior thread for details! @z_baram @drbelshort @JessicaLBolton
Just out! What factors execute enduring changes of hippocampal neurons. promoting memory deficits after early-life #stress? REST and all the rest (actually GR). REST/NRSF= a TF poised for neuronal plasticity. 👇@calizavi @BohacekLab @Cate_cholamine
Just out! What factors execute enduring changes of hippocampal neurons. promoting memory deficits after early-life #stress? REST and all the rest (actually GR). REST/NRSF= a TF poised for neuronal plasticity. 👇@calizavi @BohacekLab @Cate_cholamine https://t.co/7iJe0VLOjJ
Happy to share this paper is finally out (after >5 years of hard work and a great team effort)! 🎉We discovered the transcriptional repressor NRSF/REST programs long-term hippocampal memory deficits/neuronal stunting after early-life adversity @CellReports cell.com/cell-reports/f…
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