Benjamin Stewart @drbstewart
#singlecell #genomics 👨💻 🧬 | #kidneys 👨⚕️🏥 sanger.ac.uk/person/stewart… Cambridge, UK Joined June 2014-
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(1/8) Excited to share our latest preprint introducing ACCESS-ATAC, a high-resolution approach to measure chromatin accessibility and transcription factor binding: biorxiv.org/content/10.110…
V promising approach perturb multiome - effects of tf perturbations on chromatin accessibility and expression pmc.ncbi.nlm.nih.gov/articles/PMC11…
Great collaboration between the @FoldingGenome and Watkins labs, reporting the first Gain of Function de novo enhancer causing Mendelian disease (ST Depression Syndrome), defining a multidisciplinary path with ML to solving non-coding clinical genetics. medrxiv.org/content/10.110…
Every project is unique – like a ❄️– but after experiencing many projects it also gets pretty clear that there is pretty much a common way they unfold, once the initial idea happens:
underrated tweet.
Very cool ancient genomics
very useful package if you're in a multiplexed bind demultiplex.readthedocs.io/en/latest/inde…
Congratulations Asger This is very interesting and important work!
Congratulations Asger This is very interesting and important work!
amazing!
this is a very interesting sequence-function association for the small number of enhancers that operate a large distances. Curious principle for gene regulation -
this is a very interesting sequence-function association for the small number of enhancers that operate a large distances. Curious principle for gene regulation -
Please just let the poor patients sleep
ribosomal DNA copy number variation as a potential genetic influence on CKD risk. cell.com/action/showPdf… Associates with creatinine, cystatin C, urea, microalbuminuria 'kidney failure' rather than glomerular disease or urolithiasis... what does rDNA copy number do to the kidney?
interesting clinical pearl on very very commonly prescribed drug.
interesting clinical pearl on very very commonly prescribed drug.

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Susan Quaggin @SusanQuaggin
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Prof Liz B 🇬🇧�... @kidneydoc101
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