Gaurav Joshi @gauravjoshi
Scientist - all things microscopy🔬🔬🔬, cell & cancer biology, cell death and nanoparticles. Views my own and not my employers. Boston, MA Joined January 2009-
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Gaurav Joshi retweeted
TL1A Landscape (May 2025) - deep dive With three Phase 3 programmes running and two more on the way, TL1A blockers could reach market as soon as 2027. Key battlegrounds will be: • Speed to first approval (Merck vs Roche). • Companion biomarker - will it stand up in phase 3…
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Great data on 3D multiplex IF from Clarence and team at LSP/HMS - Paper lays out methodology for tissue processing, embedding, sectioning, labeling and imaging to enable 3D multiplexing - Comparison between 5 um and 35 um section. Definitely more information from a 35um section.
Great data on 3D multiplex IF from Clarence and team at LSP/HMS - Paper lays out methodology for tissue processing, embedding, sectioning, labeling and imaging to enable 3D multiplexing - Comparison between 5 um and 35 um section. Definitely more information from a 35um section.
Gaurav Joshi retweeted
This was one of the coolest cancer research studies of Q1 2025. cancer.gov/news-events/ca…
Gaurav Joshi retweeted
Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day on Friday 4/25. All talks will be live-streamed (no registration required) at satijalab.org/scgd25
Gaurav Joshi retweeted
Introducing RAEFISH, our lab's new flagship image-based spatial transcriptomics technology that simultaneously enables single-molecule spatial resolution and whole-genome level coverage of long and short, endogenous and engineered RNA species in cell cultures and intact tissues.
Gaurav Joshi retweeted
Online Now: Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics dlvr.it/TJnywK
Gaurav Joshi retweeted
Online Now: Navigating established and emerging biomarkers for immune checkpoint inhibitor therapy dlvr.it/TJpbC1
Gaurav Joshi retweeted
Approved NSCLC drugs since 2011. Very informative table from CCR. aacrjournals.org/clincancerres/…
Gaurav Joshi retweeted
How do cells efficiently respond to stress? Transcriptional stress responses are well-known—and in our latest study, we discover that cells use biomolecular condensation to redirect translation from old to new mRNAs 1/n biorxiv.org/content/10.110…
Gaurav Joshi retweeted
3D imaging is costly & time-consuming and input 2D images are often missing or damaged. Here we develop a generative AI workflow to interpolate and restore 3D stacks of images. For stacks of histological, IHC, MRI, light-sheet, cryo-EM images. Here: biorxiv.org/content/10.110…
Gaurav Joshi retweeted
#Cellpose 3! Not all images are perfect. Restore your images with Cellpose3 to get better segmentations, w/ @marius10p biorxiv.org/content/10.110…
Gaurav Joshi retweeted
Strawberry as you may not have seen it before (leaf surface). Having great fun with our new Ti2 @NikonInst spinning disk. Thanks for the support, #NikonHealthcareUK and @Uni_of_Essex!
Good AI vs Bad AI was science fiction. A disgruntled person might as well create Bad AI for their own revenge following a coup. Let's see what the future holds.
#askstar would the outcome be any different if India won toss and bowled first?
Single cell data failed to form clusters
Single cell data failed to form clusters
This is one of those 😎😎😎 papers in the field of microscopy. Co-illuminate your GFP with NIR and get more bang for the buck
This is one of those 😎😎😎 papers in the field of microscopy. Co-illuminate your GFP with NIR and get more bang for the buck https://t.co/qT5AoUHY3m
Gaurav Joshi retweeted
Cool new paper showing that human mitochondria internalize (endocytosis-style!) lysosomes during hypoxia. Great EM work and live-cell imaging. nature.com/articles/s4146…
Gaurav Joshi retweeted
For this Focus issue, we asked experts in bioimaging from around the world to tell us what excited them about the future of bioimage analysis for the next 5-20 years. (1/n) All Focus content can also be found here: nature.com/collections/af…
My #twitter feed has become magically better since the release of #threads. No more spam posts that I never subscribed to and a lot of more science. Thanks #Zuckerberg for improving twitter.
Light scatters. When the light from 🎆 💥 scatters through ☁️ ☁️ it’s not fun. #BostonJuly4 #July4th
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