Search results for #Calcineurin
Efficacy of #Calcineurin Inhibition in #Children With Steroid-Resistant Nephrotic Syndrome #SRNS #VisualAbstract by Morgan McCord kireports.org/article/S2468-…
Zhou et al found #RCAN1 in the brain boosts nerve activity that raises #BP by inhibiting the normal function of #calcineurin. Learn more how this discovery could lead to new treatments for brain-driven #hypertension at ahajrnls.org/4feBFlt @hlpan61 @MDAndersonNews
#Myelodysplastic Syndrome #MDSssm high unmet need. $CRVS ITKi #soquelitinib MOA suppressing CD4+ Tcells may benefit w/o immunocompromising patient. Note: #Calcineurin inhibitor #CyclosporineA (CsA) combo response rates 51% in lower-risk MDS patients. ashpublications.org/blood/article/…
#Myelodysplastic Syndrome #MDSssm high unmet need. $CRVS ITKi #soquelitinib MOA suppressing CD4+ Tcells may benefit w/o immunocompromising patient. Note: #Calcineurin inhibitor #CyclosporineA (CsA) combo response rates 51% in lower-risk MDS patients. ashpublications.org/blood/article/… https://t.co/XbbhAR24DO
Regulating #Calcium Could Help Regenerate the Heart Pharmacological or genetic inhibition of LTCC promotes #cardiomyocyte proliferation through inhibition of #calcineurin activity nature.com/articles/s4153… @TCTMD @mmamas1973 @TCTMD_Yael @ShelleyZieroth
Regulating #Calcium Could Help Regenerate the Heart Pharmacological or genetic inhibition of LTCC promotes #cardiomyocyte proliferation through inhibition of #calcineurin activity nature.com/articles/s4153… @TCTMD @mmamas1973 @TCTMD_Yael @ShelleyZieroth
“Indications and Long-Term Outcomes of Using Mycophenolate Mofetil Monotherapy in Substitution for Calcineurin Inhibitors in Liver Transplantation” Read more here: bit.ly/4ie21nG #mycophenolate #therapy #calcineurin #inhibitor #longterm #outcome #liver #transplant
##Calcineurin inhibitors nephrotoxicity
Pipeline for mapping #calcineurin targets for #pancreatitis #breakthrough #discoveries by @sohailzhusain lab @Stanford_GI ! #inspiring! #APA24
#Calcineurin inhibitors promote chronic #alloimmunity via propagation of central memory T cell subsets amjtransplant.org/article/S1600-…
Just released in #EMDB and published in @Structure_CP: 3.5 Å #Cryo-EM structure of #Calcineurin bound to #PI4KA, revealing a dual interface in both PI4KA and #FAM126A!
Wang et al found that #Calcineurin-#NFAT is linked to abnormal heart growth (#hypertrophy) across cardiac diseases. Learn more about a new way to target this pathway for treatment at ahajrnls.org/3Wmr92k @jiwang_tim @yaoweilu @FengXiao1988
🚨 New pub alert! #Calcineurin inhibitors experience in unplanned #pregnancies with active #lupus disease: A retrospective observational study dustri.com/nc/article-res… @rizacankardas @4fc021c64f83427
$CRVS ITK inhibitor #soquelitinib prevents and reverses T-cell exhaustion by preventing metabolic dysfunction in T-cells by inhibiting calcium signaling pathway (#calcineurin-NFAT).
$CRVS ITK inhibitor #soquelitinib is upstream #calcineurin inhibitor. Blocking calcium pathway (calcineurin-NFAT) prevents T-cell exhaustion in CAR-T cells by: -stopping transcription of exhaustion markers -inhibiting anabolic metabolism changes in T-cells ncbi.nlm.nih.gov/pmc/articles/P…
@euroimmun_us Should look at $CRVS novel upstream approach inhibiting ITK w/ #soquelitinib and downstream control of #calcineurin in T-cells glial/microglial cells offering safer approach to treating neural inflammation/disease including Alzheimer's and Parkinson's.
@euroimmun_us Should look at $CRVS novel upstream approach inhibiting ITK w/ #soquelitinib and downstream control of #calcineurin in T-cells glial/microglial cells offering safer approach to treating neural inflammation/disease including Alzheimer's and Parkinson's.
Video showing #calcineurin (CN) inhibition slows/stops progression of dementia, Alzheimer's, etc. $CRVS ITK inhibitor #soquelitinib mode of action same, but futher upstream and should tap straight into the benefits of CN inhibition without side effects. youtube.com/watch?app=desk…
@VJDementia @utmbhealth @adpdnet Should really look into $CRVS novel upstream approach inhibiting ITK w/ #soquelitinib and downstream control of #calcineurin in glial/microglial cells offering safer approach to treating neural inflammation/disease including Alzheimer's and Parkinson's.
@VJDementia @utmbhealth @adpdnet Should really look into $CRVS novel upstream approach inhibiting ITK w/ #soquelitinib and downstream control of #calcineurin in glial/microglial cells offering safer approach to treating neural inflammation/disease including Alzheimer's and Parkinson's.
Alzheimer's, Parkinson's, MS, ALS are inflammatory diseases likely caused by dysregulation of #calcineurin/NFAT. $CRVS upstream inhibition of ITK in T-cells w/#soquelitinib can turn off calcineurin/NFAT downstream Huge potential for neurological diseases!
Alzheimer's, Parkinson's, MS, ALS are inflammatory diseases likely caused by dysregulation of #calcineurin/NFAT. $CRVS upstream inhibition of ITK in T-cells w/#soquelitinib can turn off calcineurin/NFAT downstream Huge potential for neurological diseases! https://t.co/bLsDC0Lf3U
@ScienceofPD @tuite002 Should really look into $CRVS novel upstream approach inhibiting ITK w/ #soquelitinib and downstream control of #calcineurin in glial/microglial cells offering safer approach to treating neural inflammation/disease including Alzheimer's and Parkinson's.
@ScienceofPD @tuite002 Should really look into $CRVS novel upstream approach inhibiting ITK w/ #soquelitinib and downstream control of #calcineurin in glial/microglial cells offering safer approach to treating neural inflammation/disease including Alzheimer's and Parkinson's.
