Hwajin Lee @hwajin2k
Currently at UPPThera, Cheif Operating Officer; Seoul National University, Adjunct PI Formerly at Celltrion, Inc. Ph.D in Cellular and Molecular Medicine, JHSOM Incheon, South Korea Joined June 2011-
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Feature Selection and Dimension Reduction for Single Cell RNA-Seq based on a Multinomial Model biorxiv.org/content/10.110…
Personal News: Today marked a new beginning, and a beginning’s end. I am grateful for the support I received at @IcahnMountSinai where I started my career as an independent researcher. I am looking forward to my new role at @C2iGenomics, an innovative liquid biopsy company.
Exciting to see @KirstenKubler (now faculty at BIH @berlinnovation & @ChariteBerlin) present this recent collaborative work b/t @getz_lab and Dr. Rinath Jeselsohn on tamoxifen-associated #UterineCancer at #SABCS21! Check out the press release in her 🧵 to learn more!!
Exciting to see @KirstenKubler (now faculty at BIH @berlinnovation & @ChariteBerlin) present this recent collaborative work b/t @getz_lab and Dr. Rinath Jeselsohn on tamoxifen-associated #UterineCancer at #SABCS21! Check out the press release in her 🧵 to learn more!!
Important study about #IMiD neosubstrate SAR with design implications for molecular glue & CRBN-targeted #PROTACs (incl. dual MoA PROTACs like KT-413, NX-2127). Of note, comprising ARV-110's magic fluorine IMiD warhead. biorxiv.org/content/10.110… @biorxivpreprint @ChoudharyLab
Kristen Baltgalvis @VividionRx @BayerPharma sharing first data for a so far untouched E3 ligase highjacked with covalent binders for bifunctional degrader applications. Further of note: cell type variability of PROTACs & E3 fractional engagement data @Undruggable #TPD21
Impressive data shared by Ryan Potts @Amgen about how they QUALITY check previously unused E3 ligases for #PROTAC applications. Clearly showing how many more ligase are still out there to be highjacked for degrading disease causing proteins. @Undruggable #TPD21
Our recent work combining in vivo CRISPR screens, E3 ligase protein degradation, and cancer immunology. Congratulations to Xiaoqing, @ShengqingGu @ctokheim and Binbin, and collaborator @maverybrown !
Our recent work combining in vivo CRISPR screens, E3 ligase protein degradation, and cancer immunology. Congratulations to Xiaoqing, @ShengqingGu @ctokheim and Binbin, and collaborator @maverybrown !
science.sciencemag.org/content/373/65… gastrojournal.org/article/S0016-… The two articles (one from myself and Dr.Shivdasani's group) both point towards the gastric cell-of-origin for Barrett's Metaplasia and Esophageal Adenocarcinoma. Hope more breakthrough works on cancer cell-of-origin would come up!
Our editorial on the excellent MSK paper by Ceyhan-Birsoy et al. is out academic.oup.com/jnci/advance-a…
That @ArvinasInc ER-degrading #PROTAC ARV-471 is lenalidomide-based was one surprise. The bigger surprise is that they separated the imide epimers to provide a diastereomerically pure degrader. This question has been around for some time, but I never saw it done before. #AACR21
Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa medrxiv.org/content/10.110…
Nice works from the Sanger institute. These data, along with other pre-existing datasets, would boost researches on revealing how the somatic mutation landscape is formed during the course of normal aging and cancer progression.
Nice works from the Sanger institute. These data, along with other pre-existing datasets, would boost researches on revealing how the somatic mutation landscape is formed during the course of normal aging and cancer progression.
🔴Review about the major mutation biases that operate across the cancer genome and the molecular mechanisms that cause them. By @BenLehner @CRGenomica and @FranSupek @IRBBarcelona ➡️bit.ly/CRG_MutationsH…
🔴Review about the major mutation biases that operate across the cancer genome and the molecular mechanisms that cause them. By @BenLehner @CRGenomica and @FranSupek @IRBBarcelona ➡️bit.ly/CRG_MutationsH…
A (brief) tweetorial (@CharlesSwanton request) for our latest work - Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia nature.com/articles/s4158…
Analyzing these types of data would also reveal how the environmental agents intertwine with the chromatin landscape or other factors associated with the mutation accumulation patterns for normal tissues and cells. cell.com/cell/fulltext/…
Great work with really nice presentation!
Great work with really nice presentation!
Apparently this would be more of a underrated issue for some of the minorities. Hope much more genomics data from Asian and other races would come out and get attentions by scientific and medical communities.
Apparently this would be more of a underrated issue for some of the minorities. Hope much more genomics data from Asian and other races would come out and get attentions by scientific and medical communities.
James K .Filan 🇱�... @FllenLew
132 Followers 2K Following Defense lawyer. Former federal prosecutor.Not legal or financial advice. I'm not your lawyer. I won't ask you to DM me. i have no other social media accounts.
Eleanor Terrett | PRI... @EleanqrTerrett
49 Followers 1K Following Journalist & Host @CryptoAmerica_ • Former @FoxBusiness • Citizen of 🇺🇸🇬🇧 • Mother of Cats🐈 • Breaker of News🗞️ • THIS IS MY ONLY X ACCOUNT! •
Nensloa @Nensloagt2L
41 Followers 4K Following
Tamrin Chowdhury @TamrinChowdhury
75 Followers 490 Following Enjoying life to its fullest. Celebrating the present and dreaming about the future. Postdoc@YaleNeurosurgery Verhaak lab.Brain tumors.Genomics.Computational
The Single-Cell Ninja... @Sc_Ninjas
6K Followers 4K Following Disseminating knowledge about single-cell technology. Like/RT ≠ endorse
Majeed Shaikh @MjMajeedPharma
400 Followers 5K Following #PhD Scholar at #University de Montreal #OrganicSynthesis #MedicinalChem #Almamater #CSIR-IIIM Jammu, #JamiaHamdardUniversity #NewDelhi.
Andy @Andy68255998
78 Followers 2K Following
nylee @nylee22260927
1 Followers 66 Following
ComInnex Inc. @cominnex
236 Followers 2K Following ComInnex Inc. is a specialist #chemistry #research organization, follow us to stay tuned about quality custom #synthesis & novel #technologies!
Amiria @Amiria92813372
1K Followers 5K Following i am loving and emotional girl, i love playing with little kids, i love honest people, i love caring and loving people, i hate war, i hate lies, i hate rapiest
Dan Nomura @DanNomura
19K Followers 9K Following Professor of Chemical Biology and Molecular Therapeutics at UC Berkeley; Departments of Chemistry and Molecular and Cell Biology; Co-Director of @MTI_UCB
Dana-Farber Chemical ... @DFCI_ChemBio
4K Followers 1K Following We use chemical creativity to tackle hard biology questions, target the “undruggable”, & train the next generation. Part of @DanaFarber research universe.
Milka Kostić, PhD @MilkaKostic
4K Followers 3K Following Director of @DFCI_ChemBio pursuing innovation, translation & transformation through #chemicalbiology. Opinions and views strictly my own!
Heung Sik Hahm @hahm12
56 Followers 399 Following IM-MS for Glycan, Automated Glycan Assembly, Glyconeer 2.1, Carbohydrate vaccines, SuTEx Chemistry, now Moving beyond SuTEx. Synyhesis of many HHS-XXXX
Taeyoung Hwang @TaeyoungHw
53 Followers 122 Following
Byunggyu Ahn @byunggyuahn
268 Followers 745 Following 👋 Staff Engineer at MongoDB 🍃 Billing, Web Ad, Game Servers & Clients🕹 Google, EA Seoul, Nexon Japan & Korea🇰🇷 PhD dropout 🥇IOI/KOI 🎓JHU, SNU, Stanford
GJ @jelee0710
2 Followers 43 Following
Gordon G. Chang @GordonGChang
396K Followers 929 Following Author of Plan Red: China’s Project to Destroy America, The Coming Collapse of China, and China Is Going To War.
James K. Filan 🇺�... @FilanLaw
258K Followers 255 Following Defense lawyer. Former federal prosecutor. Not legal or financial advice. I’m not your lawyer. I won't ask you to DM me. I have no other social media accounts.
Eleanor Terrett @EleanorTerrett
256K Followers 3K Following Journalist & Host @CryptoAmerica_ • Former @FoxBusiness • Citizen of 🇺🇸🇬🇧 • Mother of Cats🐈 • Breaker of News🗞️ • THIS IS MY ONLY X ACCOUNT! •
The Economic Ninja @economyninja
92K Followers 586 Following We want a million people to make a million dollars. We bring you financial education and news that school never taught you.
Protein-Degraders @ProtDegraders
488 Followers 434 Following All things TPD! Protacs, molecular glues, ligases, proteasome, proximity induced
Eric Trump @EricTrump
5.9M Followers 1K Following Executive Vice President of The @Trump Organization. Husband to @LaraLeaTrump. Advocate of @StJude. @WorldLibertyFi @AmericanBTC #MakeAmericaGreatAgain
JackTheRippler ©️ @RippleXrpie
424K Followers 521 Following | CRYPTO NEWS IN REAL TIME |🥇SELFMADE | I TOLD YOU TO BUY XRP AT 10 CENTS | *Posts are my own thoughts & not financial advice*
Elon Musk @elonmusk
225.3M Followers 1K Following
Donald J. Trump @realDonaldTrump
108.8M Followers 53 Following 45th & 47th President of the United States of America🇺🇸
Alyssa Verano @alysverano
117 Followers 148 Following Medicinal chemist | Targeted protein degradation, molecular glues, oncology chemistry
Simona Cristea @simocristea
9K Followers 497 Following cancer genomics AI scientist; head of Data Science & AI and group leader @DanaFarber_Hale; research scientist @Harvard; phd @eth.🇷🇴🇸🇪🇨🇭🇺🇸
Dan Landau @landau_lab
11K Followers 3K Following Somatic evolution, cancer genomics, epigenomics (Weill Cornell/New York Genome Center). Hemato-oncologist (NYP). Discl.: https://t.co/7TBNcbcVCP
Rahul Satija @satijalab
28K Followers 354 Following Core Member, New York Genome Center; Professor, Biology, NYU
Joel Wagner @joelpwagner
108 Followers 512 Following Reimagining cancer medicine in Oncology Data Science @NovartisScience. Formerly @jacksonlab, @MITdeptofBE, @Cambridge_Uni, @UWMadison, @WVNYSCamp. He/him.
Yingying Cao @yingyingcaoyyc
652 Followers 316 Following Postdoc @theNCI | Research Interests: Omics data analysis / Oncology / Virology | Tweets are my own👩🏻💻👩🏻🏫
Keith Hornberger @KRHornberger
12K Followers 260 Following TPD-med chem-hiking-cocktails / while I have a connection to Arvinas, all opinions expressed are mine and do not represent the views or positions of the company
Kymera Therapeutics @KymeraTx
3K Followers 146 Following Advancing the field of targeted protein degradation to deliver breakthrough medicines for previously untreatable diseases
The Single-Cell Ninja... @Sc_Ninjas
6K Followers 4K Following Disseminating knowledge about single-cell technology. Like/RT ≠ endorse
Andy @Andy68255998
78 Followers 2K Following
Single Cell papers @scell_papers
12K Followers 23 Following A twitter bot account for papers employing sequencing of single cells
Dennis X. Hu @DennisWhom
4K Followers 725 Following founder & CEO @drughuntersite after drug discovery in pharma/biotech (Genentech, RAPT Therapeutics) - discover faster in two min at https://t.co/lyNyXN7Pof
Arvinas @ArvinasInc
4K Followers 273 Following A revolutionary approach to protein degradation therapeutics. https://t.co/eppnBxVbQi
Taavi Neklesa @TaaviNeklesa
505 Followers 302 Following all things to do with induced proximity and oncology; Androgen Receptor targeting new modalities
Guillaume Laconde @Glaconde34
5K Followers 110 Following Medicinal chemist, PROTAC and #TPD technology OXELTIS Scientist, https://t.co/F8c4eERuOA Communication Deputy for the SCT, https://t.co/8j34whJXIQ Tweets = my own.
Milka Kostić, PhD @MilkaKostic
4K Followers 3K Following Director of @DFCI_ChemBio pursuing innovation, translation & transformation through #chemicalbiology. Opinions and views strictly my own!
Dana-Farber Chemical ... @DFCI_ChemBio
4K Followers 1K Following We use chemical creativity to tackle hard biology questions, target the “undruggable”, & train the next generation. Part of @DanaFarber research universe.
Alessio Ciulli @alessiociulli
6K Followers 393 Following Prof @Dundeeuni. Founder and Director @UoDCeTPD. Founder @AmphistaThera. We develop molecules that induce protein interactions and degradation
Dan Nomura @DanNomura
19K Followers 9K Following Professor of Chemical Biology and Molecular Therapeutics at UC Berkeley; Departments of Chemistry and Molecular and Cell Biology; Co-Director of @MTI_UCB
Chris Parker @_chrisgparker_
2K Followers 777 Following Professor @scrippsresearch | Department of Chemistry | chemical biology & chemical proteomics
MPI Dortmund @mpimoph
2K Followers 614 Following 'Bridging scales' from #smallmolecules to #cells. How can we combat the development of #humandiseases like #cancer? Max Planck Institute of Molecular Physiology
Kevan Shokat @kevansf
8K Followers 1K Following
bryan dickinson @chembioBryan
6K Followers 1K Following chemical/synthetic biologist, Luddite trying find better ways to make molecules that do important stuff, dad, @uchicago professor of chemistry
Heung Sik Hahm @hahm12
56 Followers 399 Following IM-MS for Glycan, Automated Glycan Assembly, Glyconeer 2.1, Carbohydrate vaccines, SuTEx Chemistry, now Moving beyond SuTEx. Synyhesis of many HHS-XXXX
Dana-Farber News @DanaFarberNews
6K Followers 561 Following Your official source for @DanaFarber Cancer Institute news | Research, science, and innovation | Media requests: [email protected]
Gad Getz Laboratory @getz_lab
2K Followers 0 Following Twitter Page for The Getz Lab @MGHCancerCenter and @broadinstitute | Computational genomics of #cancergenes
Matthieu Schapira @mattschap
1K Followers 117 Following Structural/computational chemistry - CACHE challenges - @mattschap.bsky.social
Craig Crews @CraigMCrews
9K Followers 951 Following Yale Professor, Founder of @ArvinasInc, Halda Therapeutics, https://t.co/YoR6Yo3d3u, @[email protected]
National Cancer Insti... @theNCI
224K Followers 4K Following The U.S. government’s agency for cancer research. Part of @NIH. Engagement ≠ endorsement. Questions about cancer? Reach us here: https://t.co/yQAi9x4Obg
Manolis Kellis @manoliskellis
29K Followers 4K Following Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstitute
Ben Lehner @BenLehner
5K Followers 4K Following Head of Generative and Synthetic Genomics @sangerinstitute; Systems + Synthetic Biology @CRGenomica; Co-founder https://t.co/5N3PvqNXec https://t.co/l6NKYFgZBP
Gaddy Getz @gaddyg
1K Followers 440 Following
Edwin Cuppen @ecuppen
849 Followers 140 Following Edwin Cuppen is scientific director of the Hartwig Medical Foundation a nonprofit organisation that aims to improve cancer care by whole genome sequencing
Inigo Martincorena @imartincorena
5K Followers 564 Following Scientist. Group leader at the Sanger Institute, Cambridge UK. Somatic evolution in normal tissues, cancer and ageing. Now more active in Bluesky🦋.
Timothy Chan @GeneCollector
5K Followers 699 Following Chair, Global Center for Immunotherapy, Cleveland Clinic Health System, @ClevelandClinic; Professor of Medicine; fan of tennis, coral reefs, Legos; views my own
Charles Swanton @CharlesSwanton
16K Followers 812 Following Cancer Evolution and Genome Instability, Lung Oncologist Air Pollution and Drug Resistance Fair Weather 🚴
Rafael Irizarry @rafalab
30K Followers 493 Following Applied statistician. I tweet data-driven observations, data science educational materials, academic research updates, and the occasional joke.
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