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Jishnu Das @jishnu1729

Asst Prof - Univ of Pittsburgh SOM (https://t.co/QXxIOm00Zv). Systems immunologist. Views world as networks at different scales. 'Transformed' engineer. Avid reader. jishnulab.org Pittsburgh, PA Joined August 2013
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Jishnu Das @jishnu1729

a month ago

Thank you very much @naturemethods for this Research Highlight describing our new interaction language model, SWING, that learns the lexicon of protein and peptide interactions. nature.com/articles/s4159…

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Nature Methods @naturemethods

a month ago

Thank you very much @naturemethods for this Research Highlight describing our new interaction language model, SWING, that learns the lexicon of protein and peptide interactions. nature.com/articles/s4159…

Jishnu Das retweeted
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Nature Methods @naturemethods

a month ago

Read the Research Briefing on SWING, here! nature.com/articles/s4159…

naturemethods Profile Picture

Nature Methods @naturemethods

a month ago

Read the Research Briefing on SWING, here! nature.com/articles/s4159…

Jishnu Das retweeted
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Cristina Padilla MS, MD @cris_padillaMD

a month ago

Pittsburgh group presenting at the 19th International Workshop on Scleroderma Research! @PittRheum @PittDeptofMed @jishnu1729

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Jishnu Das @jishnu1729

a month ago

Thanks a lot @naturemethods for highlighting SWING, a generalizable biologically-inspired interaction #language_model that learns that lexicon of peptide and protein interactions & the impact of #genetic #variation on these interactions. #ML

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Nature Methods @naturemethods

a month ago

Thanks a lot @naturemethods for highlighting SWING, a generalizable biologically-inspired interaction #language_model that learns that lexicon of peptide and protein interactions & the impact of #genetic #variation on these interactions. #ML

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Jishnu Das @jishnu1729

a month ago

Today in @naturemethods, we define a new lexicon for protein/peptide interactions. SWING is a generalizable zero-shot interaction #language_model that outperforms pLMs in multi-context predictions of the impact of genetic variation on interactions. #ML nature.com/articles/s4159…

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Jishnu Das @jishnu1729

2 months ago

Full house to start the new #CSI COSI at ISMB 2025 that @ferhatay and I are co-chairing. Looking forward to a great set of talks!

Jishnu Das retweeted
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Ferhat Ay @ferhatay

2 months ago

For CSI COSI, I am very thankful to my co-chair @jishnu1729 and steering committee @YuriPritykin , @haticeulku, Aly Azeem Khan. And everyone who submitted their for consideration for this session iscb.org/ismbeccb2025/p…

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Jishnu Das @jishnu1729

2 months ago

I came to the US in 2010 as a PhD student & it transformed my life. Privileged to lead (since 2020) a #systems #immunology lab comprising an incredible group of men & women. This country gave me opportunities I couldn't have dreamed of elsewhere. Proud #US citizen. Happy 4th all!

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Jishnu Das @jishnu1729

4 months ago

Check out our recent review in @MolTherapy about how machine learning approaches enable the discovery of therapeutics across domains cell.com/molecular-ther…. We cover a range of #ML techniques with wide applications to #cellulartherapy.

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Jishnu Das @jishnu1729

5 months ago

Check out our recent paper in @JCI_insight where we use interpretable #ML to uncover signatures of pathogenesis in localized #scleroderma (#morphea). insight.jci.org/articles/view/…

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Jishnu Das @jishnu1729

10 months ago

Thank you @JCI_insight for highlighting our collaborative work with @corrine_kliment using interpretable #ML approaches to uncover a novel role for GSN in #COPD. We used a range of approaches including a recent flagship method from our lab - SLIDE (nature.com/articles/s4159…).

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JCI insight @JCI_insight

10 months ago

Thank you @JCI_insight for highlighting our collaborative work with @corrine_kliment using interpretable #ML approaches to uncover a novel role for GSN in #COPD. We used a range of approaches including a recent flagship method from our lab - SLIDE (nature.com/articles/s4159…).

Jishnu Das retweeted
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56 years ago

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Aniruddh Sarkar @anisircar

10 months ago

If you're at @ASTMH #TropMed24 do add our Systems Immunology of Tropical Diseases symposium (138) to your schedule for Sat Nov 16th. Speakers include @nadegenziza, Dr Elizabeth Aitken & my co-chair @jishnu1729. Exciting talks across AI/ML, Malaria, TB & NTDs incl Schistosomiasis.

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Jishnu Das @jishnu1729

10 months ago

Thank you @CellReports for highlighting our work showing how #protein #networks with structural resolution can identify #immunomodulatory variants in infectious disease. Key coding variants often missed by conventional #GWAS can be picked up by our approach.

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Cell Reports @CellReports

10 months ago

Thank you @CellReports for highlighting our work showing how #protein #networks with structural resolution can identify #immunomodulatory variants in infectious disease. Key coding variants often missed by conventional #GWAS can be picked up by our approach.

Jishnu Das retweeted
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Cell Reports @CellReports

10 months ago

Uncovering cell-type-specific immunomodulatory variants and molecular phenotypes in COVID-19 using structurally resolved protein networks dlvr.it/TG1HSf

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Jishnu Das @jishnu1729

11 months ago

Super fun collaboration with @poholeklab now out in Nature Immunology - nature.com/articles/s4159… . We use interpretable #machine_learning to help identify spatial microniches of IL2 in a murine model of allergic #asthma.

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PoholekLab @poholeklab

11 months ago

Super fun collaboration with @poholeklab now out in Nature Immunology - nature.com/articles/s4159… . We use interpretable #machine_learning to help identify spatial microniches of IL2 in a murine model of allergic #asthma.

Jishnu Das retweeted
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The Nobel Prize @NobelPrize

11 months ago

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

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Jishnu Das @jishnu1729

12 months ago

Study from my lab out today in @ScienceTM - using interpretable #ML on deep #antibody profiles, we uncover mechanisms of schistosomiasis pathogenesis. Collaborative work with @anisircar & @Fairley_NTD. Co-led by @TrirupaChakrab2 & Anushka Saha. science.org/doi/10.1126/sc…

Jishnu Das retweeted
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Aniruddh Sarkar @anisircar

12 months ago

Great to see this out today in @ScienceTM! Collaborative work with @jishnu1729 at Pitt & @Fairley_NTD at Emory and collaborators at CDC & in Brazil. Led by Anushka (@CoulterBME alum) in my lab & @TrirupaChakrab2 at Pitt. Antibody-omics for schistosomiasis diagnostics & beyond 👇

Jishnu Das retweeted
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PittRheum @PittRheum

12 months ago

Congratulations to all awardees especially to our own @Niranjana89 !

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PittDeptofMed @PittDeptofMed

12 months ago

Congratulations to all awardees especially to our own @Niranjana89 !

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