Lum Lab @lum_lab
Julian Lum's Lab - Autophagy, cancer & immunometabolism. "If you don't fail, you aren't taking enough risks". Views are our own. Tweets by Julian-JJL LumLab.ca Victoria, British Columbia Joined February 2019-
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Lum Lab retweeted
Our team is excited and honored to see our new method, HT SpaceM, for high-throughput single-cell metabolomics published in Cell! sciencedirect.com/science/articl… 👇
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Lum Lab retweeted
RESEARCH | @britta_phd, @HannahPrendevil, @lynchielydia et al. (@tcddublin, @harvardmed, @Princeton) Animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based fats do not. nature.com/articles/s4225…
Lum Lab retweeted
Just published in @NatureComms! 🚨 We tracked #immune cell changes in blood during anti-PD-1 treatment and identified a non-invasive, early on-treatment biomarker of #immunotherapy response in #headandneck #Cancer. 🧵(1/5) 📜 doi.org/10.1038/s41467…
Lum Lab retweeted
New! Online now: NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism dlvr.it/TMkFYT
Lum Lab retweeted
@biorxivpreprint Controllable Sleeping beauty mutagenesis provides a platform for functional screening of genes that improve T cell therapeutic phenotypes, including a dose-dependent role of BACH2 in enhancing CAR-T cell function during chronic stimulation biorxiv.org/content/10.110…
Lum Lab retweeted
Highly Efficient Gene Knockout in Tumor-Infiltrating Lymphocytes by Adenine Base Editing dlvr.it/TMdzjy
Lum Lab retweeted
I am thrilled to finally share my lab's first paper showing that sucralose consumption reduces immunotherapy efficacy in cancer, published NOW in @CD_AACR ! Let's break it down. 1/n aacrjournals.org/cancerdiscover…
Lum Lab retweeted
d-cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1 go.nature.com/45eETlB
Lum Lab retweeted
The rise of China’s pharmaceutical industry from 2015–2024 nature.com/articles/d4157… This new article analyses the growth in drug innovation in China, the underlying environmental factors and strategic trends such as the outlicensing of assets originating in Chinese companies
Lum Lab retweeted
Nature research paper: Imidazole propionate is a driver and therapeutic target in atherosclerosis go.nature.com/4m6m6OZ
Lum Lab retweeted
New #JITC article: T cell-specific non-viral DNA delivery and in vivo CAR-T generation using targeted lipid nanoparticles bit.ly/4m4iBIy @NadineSaberr
Lum Lab retweeted
Engineering the gut microbiome in people with hyperoxaluria to avoid kidney stones science.org/doi/10.1126/sc… @ScienceMagazine
Lum Lab retweeted
Super excited to share new review on metabolic stress and adaptations in pancreatic cancer to these stresses from @ColinSh21573670 jci.org/articles/view/… 1/6
Lum Lab retweeted
Review @NatImmunol The role of gut microbial metabolites in the T cell lifecycle nature.com/articles/s4159…
Lum Lab retweeted
#Throwback COMMENT | @kadzuis Subcellular quantitative imaging of metabolites at the organelle level nature.com/articles/s4225…
Lum Lab retweeted
On the root cause of global obesity pnas.org/doi/suppl/10.1… science.org/content/articl… washingtonpost.com/wellness/2025/…
Lum Lab retweeted
CAR-T cells containing CD28 versus 4-1BB co-stimulatory domains show distinct metabolic profiles in patients dlvr.it/TLwDHc
Lum Lab retweeted
A patient page for GLP-1 drugs and importance of integration of lifestyle factors with these meds jamanetwork.com/journals/jamai… jamanetwork.com/journals/jamai…
Lum Lab retweeted
#NatMetabPicks | In @CD_AACR led by L Zitvogel, @CBigenwald et al (@GustaveRoussy) Oral supplementation with Akkermansia spp. improves the efficacy of CAR-T cells against B cell lymphoma. aacrjournals.org/cancerdiscover…
Lum Lab retweeted
Microbiota-driven antitumor immunity mediated by dendritic cell migration @Nature nature.com/articles/s4158…
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