Mischel Lab @mischellab
The Mischel lab studies extrachromosomal oncogene amplification and altered metabolism in cancer. Account managed by lab members. Retweets are not endorsement. paulmischellab.org Stanford, CA Joined November 2019-
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The eDyNAmiC team will investigate #ecDNA, found in around a third of cancers, hoping to develop much needed treatments for people whose cancer is driven in this way Congratulations Paul Mischel (@mischellab @StanfordMed) and the team, funded by @CR_UK and @theNCI 3/n
It is very exciting to be part of the eDyNAmiC team to take the #CancerGrandChallenges and trackle cancer evolution driven by ecDNA. Thanks for the big support of @CancerGrand @QMULMaths @QMBCI
It is very exciting to be part of the eDyNAmiC team to take the #CancerGrandChallenges and trackle cancer evolution driven by ecDNA. Thanks for the big support of @CancerGrand @QMULMaths @QMBCI
Looking forward to working with @anton_gh, @michelle_monje, @huang_weini, @MariamJHanjani, @SihanSean, @BenjaminWerner_, @HowardYChang, @cbailey_58, @VineetBafna3, and many others.
Looking forward to working with @anton_gh, @michelle_monje, @huang_weini, @MariamJHanjani, @SihanSean, @BenjaminWerner_, @HowardYChang, @cbailey_58, @VineetBafna3, and many others.
Congratulations to @kinglhung, @KatieEYost, @HowardYChang and colleagues on this landmark discovery published today in @Nature. We are thrilled to have worked together with you on this.
Congratulations to @kinglhung, @KatieEYost, @HowardYChang and colleagues on this landmark discovery published today in @Nature. We are thrilled to have worked together with you on this.
Congrats to my former colleague Junfeng Bi @mischellab for the new paper! He found that GBM, the most lethal brain tumor, is sensitive to SMPD1 inhibition. Adding antidepressant fluoxetine to standard-of-care chemotherapy can improve patient survival. cell.com/cell-reports/f…
We are thrilled to join the wonderful @Stanford_ChEMH community to continue our research into extrachromosomal DNA!
We are thrilled to join the wonderful @Stanford_ChEMH community to continue our research into extrachromosomal DNA!
Excited to see this paper out. Joint work led by the @CalifanoMd and @VineetBafna3 labs. We characterized frequent human-HPV hybrid circular extrachromosomal DNA #ecDNA in HPV+ oropharyngeal cancer patients. clincancerres.aacrjournals.org/content/early/…
In uveal melanoma, PRC1 loss leads to gene de-repression, chromosome segregation errors, CIN, rupture-prone micronuclei & release of dsDNA into the cytosol, which activates the cGAS-STING pathway to induce inflammatory signalling & confers a poor prognosis nature.com/articles/s4146…
(1/2) Insights from #scRNAseq, coupled with fundamental #cell_biology, reveals loss of #PRC1 in a subset of tumor cells underlies transition of #uveal #melanoma from indolent to #metastatic phenotype. nature.com/articles/s4146… A team effort with @Samuel_Bakhoum @mischellab
We are thrilled to announce that @MathieuBakhoum joined @YaleMed as Assistant Professor. Congratulations Mathieu and best wishes on your next and exciting endeavor @Yale! His lab is recruiting! Apply if you are interested in #melanoma and #epigenetics bakhoumlab.org
We are thrilled to announce that @MathieuBakhoum joined @YaleMed as Assistant Professor. Congratulations Mathieu and best wishes on your next and exciting endeavor @Yale! His lab is recruiting! Apply if you are interested in #melanoma and #epigenetics bakhoumlab.org
Thankful for the outstanding mentorship I received from Paul Mischel @mischellab and colleagues @UCSDHealth. And looking forward to making new friendships and collaborations @Yale. New Haven, here we come! 4/4
Very honored that our grant proposal on #ecDNA in cancer is shortlisted for the #CancerGrandChallenges prize! Grateful to the @CancerGrand. Thank you to all of our team members! And Looking forward to the exciting work ahead.
Very honored that our grant proposal on #ecDNA in cancer is shortlisted for the #CancerGrandChallenges prize! Grateful to the @CancerGrand. Thank you to all of our team members! And Looking forward to the exciting work ahead.

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