Targeting DNA damage in ageing: towards supercharging DNA repair nature.com/articles/s4157…
This new Review discusses approaches to pharmacologically mitigate the adverse effects of DNA damage to prevent mutation-driven cancers and mitigate age-related degenerative diseases
New Huang lab publication. A comprehensive review of nanopore environmental analysis. And, it is open access, which should be convinient for most readers. pubs.acs.org/doi/10.1021/ja…
[Review]Toward single-molecule protein sequencing using nanopores. Author predict that, more likely than not, nanopores will be capable of identifying full-length proteins at the single-molecule level and with single-amino acid resolution, paving the way to single-molecule…
“The leaders of the Human Genome Project always knew they were just starting a conversation”
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do
go.nature.com/3Ck1qBP
We received the hard copy of the Trends in Biosensing Research book - Annina’s 1st book chapter (+ co-authors Til & Julian, aka Team Nanopore)! We covered solid-state nanopores for biomolecular analysis & detection. Thank you for this opportunity @NicolasPlumere & Fred Lisdat! 🧬
In the latest @AJHGNews article, Benedict Paten & co. highlight long-read sequencing as a single, rapid, and cost-effective alternative to complex genetic testing for monogenic disorders. 🔗Read the full article: cell.com/ajhg/abstract/…#ASHG#HumanGenetics
I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) biorxiv.org/content/10.110…
Clinical evaluation of long-read sequencing-based episignature detection in developmental disorders. Nanopore sequencing-based methylome patterns were concordant with microarray-based episignatures. #nanopore#Methylationdoi.org/10.1186/s13073…
Case report! Long read Nanopore sequencing identifies precise breakpoints of a de novo paracentric inversion that disrupt the MEIS2 gene in a Chinese girl with syndromic developmental delay. #nanoporedoi.org/10.1186/s12887…
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